摘要:The concentrations of dynorphin(DYN)A1-13 in CSF and plasma were determined by RIA in mi-graine patients during attacks(n = 22) and controls(n = 10). The concentration of DYN A1-13 in CSF and plasma in patients with migraine without aura during attacks was significantly decreased compared with their controls (both P < 0. 01). The concentrations of CSF DYN A1-13 in the patients with severe lieadache was significantly decreased compared with those found. in the patients with moderate headache(P <0. 05). These data provide new evidence suggesting the involvement of the endogenous oplate peptides in the pathophysiology of migraine headache and suggest plasma and CSF DYN A1-13 levels could serve as a biological marker for this condition. After 30 min. of Tianrong acupoint thera-py, the concentrations of DYN A1-13 (P <0. 05 ) in plasma of migraine patients were significantly in-creased compared with before treatment. In the group of headache disappeared, the concentrations of plasma DYN Al M1-13 were significantly increased (P < 0. 01 ) after Tianrong acupoint therapy, but no significant changes were found in effective and ineffective groups. These suggest the analgesic proper-ties of the treatment may be ascribed to an involvement of the endogenous opiates system.
摘要:Electrochemical therapy, ECT, has been used to treat 122 cases of various kinds of tumour, a-mong them, 81 cases were malignant tumours (32 cases facial, 18 cases subaural, 16 cases labial, 15 cases tongue), and the other 41 cases were benign tumours (cavermous hemangioma at facial region 23 cases and in oral cavity 18 cases). Pathological examination of malignant tumours revealed that there were 63 cases of squamous epitheIial cancers and 18 cases of adenocarcinoma. Cavermous hemangiorna is benign tumour and congenital. Special designed and n1ade platinum needles were inserted into the tumours and the needles were connected to an instrument protucing a direct current for treatrnent.Voltage used was usually 8 volts with current 60-80 mA. The cluantity electricity applied was 100 coulombs per 1 cm in diameter of the tumour. The effectiveness of treating 81 cases malignant tumours was: CR 42 cases (51. 9% ), PR 31 cases (38. 2% ), NC 5 cases (6. 2% ) and PD 3 cases (3. 7% ).CR + PR was 73 cases (90. 1%). The effectiveness of treating 41 cases of benign hemangioma was:CR 35 cases (85. 4 % ) and PR 4 cases (9. 8 ok ). One, three ancl five year survival rates of malignant tumour patients were 95 %, 61. 7 % and 33. 3 %, respectively. While all the 41 patients with heman-gioma survived over five years aftfer treatment.
摘要:Thirty-two cases of Vascular Dementia were randomly divided into two groups: acupuncture mox-ibustion and Chinese medicine group (AG, 16 cases), and Chinese medicine group (CG, 16 cases). lt was shown that after two months treatment the therapeutic effects were significantly different (P <0. 01 )between the two groups. The effect in AG was better than that in CG. It indicates that both of the two xherapies can improve SOID and GSH-PX, reduce LPO of patients. The function ameliorated in AG was better than that in CG.
摘要:50 cases of neolarynx reconstruction under acupuncture anesthesia combining with drugs were per-formed from 1992 to 1995. We used the ear points "Lung", ."Shenmen", "Sympathetic", body points "Hegu", "Zhigou", "Futu". The patients were given pethidine, rotundine, metoclopramide imtramus-cularly 15 25 min before operation. The excellent rate was 98 %,
摘要:Silver needle therapy was used for 42 patients with severe soft tissue pain in region of neck, shoul-der and dorsum which was secondary to cervical canal stenosis (3 cases), cervical disc herniation (20cases) and trauma sequelae(19 cases). The pain-relieving effect was evaluated according to patients'own description. The results showed that it was remarkably effective in 36 cases, effective in 4 and in-effective in 2, the total effective rate was 95. 24 %. The results suggested that the silver needle therapy was significantly effective on severe soft tissue pain, because it could not only relieve muscle spasm but also accelerate the activities of central and peripheral analgesic substences.
摘要:36 cases of mastoplasia were treated by combined acupuncture with Chinese herbs, as control groups, 30 cases by acupuncture and 32 cases by Chinese herbs respectively. And the levels of serum estradiol(E2 ), progestin (P) and prolactin (PRL) were measured before and after the treatment. The results showed that the cure rate of the group by combined acupuncture with Chinese herbs was 47.22 % being higher than that by acupuncthre. The concentrations of E2 were decreased, while the ones of P were increased (P < 0.01 ) in three groups after the treatment. The concentration of PRI, was de-creased in the combined group. The results suggest that one of the effects of this therapy on mastopla-sia is regulating the functions of the hypothalamus-hypophysis-ovarysystem
摘要:One hundred patients undergoing renal transplantation were randomly divided into combined acupuncturesepidural anesthesia group (group A, points selected: Ciliao, Sanyinjiao, Taixi together with Shenshu and para-incision or Zusanli; combined with small dose of epidural block) and epidural block group(group C), each 50 patients. The initial dose and total dose of local anesthetics were 5. 6±0 .3m1 and 13. 5±1. 0ml in group A, and 14. 5±0. 4ml and 25. 4±1. 2ml in group C, respectively.There was very significant difference between the two groups(P < 0.001). During the operation the hemodynamic changes were greater in group C. Ephedrine and atropine were used in 1 and 2 cases in group A, and in 9 and 5 cases in group C, respectively. The starting time of urination of the trans-planted kidney was shorter in group A than in group C, being 209±25s and 410±47s, respectively(P< 0. 001 ). There was no significant difference in the indices of immunologic function between the two groups. The anesthetic results in group A were evaluated according to the initial dose of epidural anes-thetics. Those were excellent in 31 cases(62 % ) and good in 13 (26 % ) with the excellent-good rate 88 %.
摘要:The changes of the concentration of plasma postaglandin E2(PGE2) in 16 patients with rheuma-toid arthritis before ancl after warrn needling were observed in order to investigate the modulation mechanism of PGE2 on immunological function and the therapeutic effects of warm needling. The re-suits showed that there was a significant difference between pre- and post- treatment. The total effec-ti ve rate was 87. 5 %. The findings suggested that the concentrations of plasma PGE2 increased after warm needling and that PGE2 was involved in n1odulation of cellular immunological function mediated by T cells and in the analgetic modulation.
摘要:A topographic observation using 128 channal electric signal imaging system on early components(N20 and following 20ms) of sensory evoked potential (SEP) was carried out on ten subjects after stimulating acupoints of the Three-Yin Meridians of the Hand. Results showed when acupoint was stimulated, high voltage areas were ohserved not only in S I area but also in other regions of the cere-bral cortex, having a dynamic changlng process, this indicates there is a complicated cortical mechanism in percepting information of acupuncture. Comparing the opographic maps of SEP induced by acupuncture at different acupoints, a general similar spatiotemporal changing process of electric activity could be found and several cortical reglons, such as frontal, central, occipital and post-temporal are in-volved. All of these results .provide a new clue for us to find out the mechanism of acupunture.
摘要:The segmental distribution and proected region of primary afferent fibers of acupionts Jiexi, Zu-sanli, Futu, Shuidao, Chengman, Rugen, Wuyi, Jiache of the stomach channel and Heyang, Feng-men, Tianzhu of the bladcler channel in Substantia Gelatinoso of spinal cord and lower brain stem were examined by CB-HRP tecllnique in rabbits. The results suggest that there could be a chain of neural networks corresponding to the stomach channel of Foot Yangming in Substantia Gelatinosa of spinal cord and brain stem. The chain of neural networks run through the length of spinal cord, extending to nucleus tractus spinalis nervi trigemini. The primary afferent fibers of the stomach and bladder chan-nels might have different regional distribution respectively, and have the relative specificity of distribu-tion overlapped mutually in the substantia Gelatinosa of spinal cord.
摘要:Our previous research has shown that electro-acupuncture(EA) on "Yan.glinguan (GB 34) and "Wudaozhenchanqu" points could make the tinles of rotation of rat model of parkinson's disease (PD)reduce remarkely than that of control group. This research aimed at studying the influence df EA on tyrosine hydroxylase(TH) in dopaminerngic neurons pf substantia nigra(SN) of rnidbrain of PD rat.The result showed that some of TH-immunoreactive(iR) cells were found in normal side of SN while lesioned side of SN only contained very few of iR cells. Lots of iR cells appeared in adrenal medulla The reaction of immunqfluorescence of TH in both SN and adrenal medulla of EA group was strongel than that of control group. The result suggests that EA may regulate the activity of TH.
摘要:The aim of the. work was to study the effects of capsaicin (Cap) blocking afferent C fibers of n.peroneus communis innervating "Zusanli" and the influence of Cap on analgesia produced by elec-troacupuncture (EA) at "Zusanli".The highest antidromic C waves of n. peroneus communis in rats were recorded. 1 % 1. 5% capsaicin soi 25μl were topically applied on the nerve between the electrodes of stimulation and record,and the changes of C wave amplitude were analysed.After 1 % Cap was applied to the nerve, the C waves were immediately reduced to 68. 3 % of con-trol before Cap treatment and kept at 55. 4 % for 45 minutes (P < 0. 001, n =9), having not been re-covered but they were not yet completely blocked. The vehicle (10% Tween80 liquid paraffin) applied on the nerve have not the effects on C waves (n = 7).Then the dose of capsaicin was increased to 1. 5 % Cap sol 25μl, after it was applied on the nerve trunk, the C waves were decreased immediately to 77. 7% of control, then the C wave amplitudes were decreased to 46. 2 % (P < 0.01 ) in 5 minutes, then maintained at 54. 5 % 1. 5% capsaicin soi 25μl were topically applied on the nerve between the electrodes of stimulation and record,and the changes of C wave amplitude were analysed.After 1 % Cap was applied to the nerve, the C waves were immediately reduced to 68. 3 % of con-trol before Cap treatment and kept at 55. 4 % for 45 minutes (P < 0. 001, n =9), having not been re-covered but they were not yet completely blocked. The vehicle (10% Tween80 liquid paraffin) applied on the nerve have not the effects on C waves (n = 7).Then the dose of capsaicin was increased to 1. 5 % Cap sol 25μl, after it was applied on the nerve trunk, the C waves were decreased immediately to 77. 7% of control, then the C wave amplitudes were decreased to 46. 2 % (P < 0.01 ) in 5 minutes, then maintained at 54. 5 % 53. 3 % for 15 53. 3 % for 15 30 minutes (P < 0. 05) (n = 4). But the C waves were not yet completely blocked.When the action time of 1. 5 % capsaicin sol was prolonged for 24 hours, the C waves were de-creased in 4/6 experimental examples, and they were completely blocked only another 2 examples.The analgesia of electroacupuncture (EA) at "Zusanli" before and after 1. 5 % Cap applying on the nervi peroneus communis for 30 minutes was observed. Before Cap treatment, EA at "Zusanli" could obviously inhibit the nociceptive responses of NRM neuron induced by stimulation of rats tail tip in 0 10. 15 .20 and 30 minutes (P < 0. 05, n = 7). But after Cap, the inhibition of EA at "Zusanli" .on the nociceptive responses was clearly weakened(P >0. 05, n = 7 ). In a case (NO. 88107 ), that C wave was nearly completely b1ocked, analgesia of EA at the lateral "Zusanli" disappeared, but EA at con-tralateral "Zusanli" could still produce analgesia.It is shggested .that role of afferent C fibers in EA analgesia is very important and itidispensable,
摘要:A model of leukopenia was made by a single large dose of cyclophosphamide administrated into mice peritoneally, on the 5th day after modelling the cluster stimulating factor (CSF) in serum was determined with cellular cultrue method. Moxa cone moxibustion was applied to Dazhui (GV 14) and Geshu (BL 17), or acupuncture applied to Zusanli (ST 36) and Sanyinjiao (SP 6) once a day after modelling. The result shows that the content and activities of CSF are increased significantly.
摘要:The changes of cAMP contents in the cerebrospinal fluid (CSF) under electroacupuncture hy-pothermia and electroacupuncture hypothermia tolerance were studied in rabbits. The results were fol-lows: (1) The body temperature rose markedly after injection of the endogenous pyrogen (EP), and cAMP contents in CSF were increased rnarkedly at the same time. (2) ElectroacuPuncture could obvi-ously decreased the body temperature induced by EP and cAMP contents were also decreased apparent-ly. (3) Compared with the results of EP induced fever group, in eIectroacupuncture tolerance group there was no significant change in fehrile response and cAMP contents in CSF after elec-troacupuncture. The experimental results indicated that the continuous electroacupuncture could lead to the acupunclure hypothermia tolerance, and its mechanism might be related to cAMP contents in CSF.