摘要:The model of reversible middle cerebral artery occlusion (MCAo) was used to study effect of electroacupuncture (EA) on brain derived neurotrophic factor (BDNF) expression at ischemia cortex and infarct volume after MCAo in rats. MCA was occluded for 90 min and one hour EA was applied immediately at points of “Shuigou” and “Baihui” after cerebral ischemia. In accumulated EA group one hour EA was applied everyday till the rats were decapitated. After reperfusion 7 days, behaviour assessment ,immuohistochemistry and TTC staining were applied. Results suggested that BDNF immunoreactive cells expressed mainly in the peripheral cortex of the infarction. In accumulated EA group the expression of BDNF was higher than that in ischemia and EA group (P<0.05),and its behaviour assessment was the best.
摘要:To probe the effect of the electroacupuncture on vascular dementia and the content of adrenal corticotropic hormone(ACTH) in the hypothalamus of the ratMethods:30 SD rats were made renal hypertension(RHR) by the kidney arteries pinched with silver clipAfter 42 days,their bilateral common carotid artery were blocked repeatedly to cause cerebral ischemiaThe Hypertension-Vascular Dementia model was madeThen they were divided into model group,electroacupuncture group and medicine group(Dihydroergotoxine,DHET) with 10 in each groupThe course was 28 daysThe ability of learning and memorizing was observed by water maze,and the contents of ACTH in the hypothalamus were detected after treatmentResults:The latent period of the electroacupuncture group and medicine group was shorter than that of the model group,and that of the electroacupuncture group was shorter than medicine groupIn the hypothalamus,the content of ACTH in the electroacupuncture was lower than that in the medicine and model group(P<005,P<005),but there was no difference between the medicine group and the model group(P>005)Conclusion:It indicated that electroacupuncture therapy could promote the ability of learning and memorizing and reduce the content of ACTH in the hypothalamus of hypertensive VDIt's therapeutic effect was better than DHET
摘要:To explore the effect of acupuncture on cholinergic central nervous system in rat of Alzheimer disease as well as the way how to create the effect. Methods: Divided rats into three groups of the normal group, AD group and the acupuncture group. Observed respectively the behavior alteration of rats before and after acupuncture, and observed the change of senile plaques (SPs) and neurofibrillary tangles (NFT) in cerebral cortex and hippocampus by special staining for SPs. Results: The rats of acupuncture group were found the behavior had better improvement and the SPs number was decreased, but NFT hadn't evidently changed. Conclusion: Acupuncture can improve rat's function of cholinergic central nervous system.
摘要:Electrically stimulating greater splanchnic nerve(GSN) was used as an experiment model of visceral pain.The spontaneous firings of 176 stimulus-relative neurons in anterior cingulate gyrus(ACG)were analyzed by means of the intracellular recording techniques of glass microelectrode in cats.According to characteristics of the evoked response to stimulating GSN,stimulus-relative neurons could be classified into visceral nociceptive neurons(VNNs,8401%)and visceral non-nociceptive neurons(NVNNs,1591%).The main findings were as follows:(1)The percentage of number of spontaneous firing neurons was significantly higher in VNNs than in NVNNs.(2)The resting membrane potential of the former was significantly lower than that of the latter.(3)Modes and frequency of spontaneous discharges of both were not obviously different. The results indicated that there existed VNNs and NVNNs in ACG,and that the excitability of the VNNs was higher than that of the NVNNs.
摘要:The study was to determine the effect of damage to noradrenergic nerves in hippocampus on the action of anti-inflammatory and immune regulation of moxibustion,thus to probe into the mechanism of moxibustion in central regulation.Models of adjuvant arthritis(AA) in rats were made,and microinjection of 6-hydroxydopamine (6-OHDA) into hippocampus was given, and then changes in vola circumference, index of thymus and spleen,IL-6,IL-2 after moxibustion were observed. Results show that moxibustion group present obvious effects of anti-inflammatory and immune regulation(P<0.01 comparing with control group),and the effects were partly blocked by the damage to noradrenergic nerves in hippocampus (P>0.05).It indicates that hippocampus may be an important portion relating to the central information integration of moxibustion treatment,and hippocampus-hypothalamic-pituitary-adrenocortical(HPA) system may be a neurohumoral route in the action of anti-inflammatory and immune regulation of moxibustion.
摘要:To explore the mechanism of acupuncture treatment for nerve root compression syndrome,25 SD(Sprague Dawley)rats were chosen.The rats were divided into five groups:the normal group,fifteenth day model group,fifteenth day acupuncture group,thirtieth day model group,thirtieth day acupuncture group.By operation,a piece of slastic of proper size and weight was gently put on the site where L 5 nerve root origins from the dural sheath.Effects of acupuncture on nerve root ultramicrostructure were studied.Compared with the fifteenth day model group,less nerve fibers whose schwann cells were proximately normal partly demyelinated in the fifteenth day acupuncture group,the myelin sheaths were more recovered and the intraradicular edema was relieved in the thirtieth day acupuncture group.The above results suggest that acupuncture can ameliorate the ultramicrostructure of the nerve root which is compressed,and provide evidence for acupuncture treatment on lumbar nerve root compression syndrome.
摘要:The hypertensive models of rats caused by “two kidneys and a clamp” were acupunctured at the “ Zusanli” points daily for ten days The result showed that the arterial pressure of rat’s tail of acupuncture treated group was significantly lower than that of hypertensive model group (P<001) and had no significant difference compared with normal group (P>005) Acupuncturing at the “Zusanli” points had the effect of lowering blood pressure but had no influence on heart rate The effect of lowering blood pressure might be related to the mechanism of relaxing peripheral blood vessel
摘要:In the rabbit model of falling pressure induced by electroacupuncture(EA) at aorta nerve(AN),the antipressure effect of EA at “Neiguan” point (NP) and the level of PRA,A Ⅱ and Ald (before and after EA) in plasma were observed(n=12).The result suggests that there may be antagonism between NP and AN by EA during the impulse introducing to NTS,which recovers the pressure to the original points.Furthermore,the level of PRA,A Ⅱ and Ald rised after EA.It seems to be a factor in this process.
摘要:The study, selecting specific points “Shenmen” and “Shaohai” of hand-shaoyin heart meridian, observed the influence on SDHase, ATPase and tectology of cardiac muscle on hyperlipidemia in rat. The study indicated: (1)Activity of ATPase and SDHase increased, and the tectology of cardiac muscle improved obviously after EA. (2)The therapeutic effect of EA at “Shenmen” on hyperlipidemia was better than at “Shaohai”. It suggested that acupuncture could improve the status of ischemia and anoxemia, promote the energy creating and utilizing.
摘要:This work was to investigate the effects of warmed needling of “Shenshu” points on uteri, ovaria, dominant folliculi and its regulation on estrin levels. The bilateral “Shenshu” points were acupunctured with the needles warmed by burning moxas in their ends. The wet weight of uteri and ovaria, the number of dominant folliculi and the changes of estrins (E 2, P, FSH and LH) were measured and compared with that of drug group (Nilestriol), young rat control group and senile rat control group. The results showed that warmed needling of “Shenshu” points produced no obvious effects on the wet weights of uteri, ovaria and the number of dominant folliculi; It might significantly increase the level of E 2 contents, remarkably decrease the contents of FSH, improve the P level but exert no obvious influence on LH contents. This suggested that warmed needling of “Shenshu” points can distinctly improve the levels of E 2 and P contents and decrease FSH. It produced stronger regulation on E 2 and FSH than P and LH.
摘要:Morphine,IL-2 and β-EP in blood serum of rats with morphine abstinence were measured to determine the effect of electrical acupuncture on point“Zusanli”Results showed that morphine in blood serum was reduced,and IL-2,β-EP were increased after electrical acupuncture therapy.The differences between the therapy group and the control group were significant.It indicated that acupuncture could promote the elimination of residual poison,increase β-EP and regulate immunity.And the study provided the experimental bases for using acupuncture to reinforce body resistance and eliminate pathogens and to regulate blood and qi,to improve abstinence syndrome.
摘要:This work was to observe the changes of plasma endotheliolysin pre- and post- acupuncture and compare with the simple drug group. The results showed that the contents of endotheliolysin in acute cerebral infarction victims were significantly higher than that of normal people (P<0.01). The contents of endotheliolysin were obviously reduced after acupuncture (P<0.05). There had significant difference between the values of acupuncture group and simple drug group (P<0.05).
摘要:There produced satisfied effect in the treatment of cerebral infarction with “Nie Sanzhen" (a method of acupuncturing temple with three needles). This work was to observe the changes of SOD and MDA pre- and post such treatment and further explore its mechanism. The results showed that this method can significantly increase the body's capability of dispelling the free radicals and lowering the lipids' peroxidation, effectively improve the metabolic imbalance of free radicals inside the patients.
摘要:The author uses the method of combination of body and ear acupuncture therapy to treat 22 cases of insomnia, compared with 22 cases with body acupuncture therapy and 22 cases with ear acupuncture therapy respectively. The results of effectiveness: Body and ear acupuncture therapy group is proved to be 95.46%; Body acupuncture therapy group is proved to be 71.27%; Ear acupuncture therapy group is proved to be 72.73%. Statistics shows that body and ear acupuncture therapy group is obviously prior to body acupuncture therapy group and ear acupuncture therapy group (P<0.01), there is no difference between body acupuncture therapy and ear acupuncture therapy (P>0.05). This indicates that the combination therapy of body and ear acupuncture for insomnia has cooperative effect in adjusting the function disturbance of brain.
摘要:Central Choroido-retinopathy is a common ocular fundus disease which mainly damaged the macula lutea retinae. It belongs to the category of “Shizhanhunmiao" (blurring of vision) in TCM. Western drugs such as hormones, vitamins and vasodilators were used but the effects were mediocre and it was extremely easy to relapse. Good results were produced with the therapy of acupuncture.
摘要:To observe the therapeutic effect of acupuncture and moxibustion on cervical spondylosis and to analyze the curative effects on different cervical spondylosis using different methods of acupuncture and moxibustion,94 cases were classified according with corresponding diagnostic standard and were randomly divided into 2 groups:therapeutic group(acupuncture and moxibustion)and control group(western medicine).As the result,the curative effect of therapeutic group was significantly better than that of the control group (P<0.05).The study showed that acupuncture and moxibustion was one of the effective therapies to treat cervical spodylosis.Adopting different principles and therapies which suitable to different types may lead to the best curative effect.
摘要:The therapeutic method of treating aching legs by acupuncturing at Shousanli(LI 10) originated from the principle of selecting distant points, and according to the ancient TCM theory “points on the lower portion should be selected for the diseases of the upper part, points on the upper should be chosen for the diseases of the lower". Acupuncture prescription was Shousanli(LI 10), but the tender acupoint was selected. The manipulation was short-puncture. Meantime the patient was asked to move the affected leg. Treatment was given one time daily. Three times made a course.
摘要:To research on the clinical effect of the point injection and motor therapy to treat knee osteoarthritis (KOA) by means of contrast patient's trail so as to seek a new effective therapy, because of no better therapy yet in our country. Subjects and Methods: 50 patients with KOA (26 men and 24 women, aged 41~76 years, mean 59.6±6.2) were divided randomly into trail group 30 cases and control group 20 cases. The former was treated with Salviae Miltiorrhizae Radix point injection (Salviae Miltiorrhizae Radix injection 4 ml, injected in Yang Lingquan and Dubi of the affected leg, one time every other day×4 weeks) and motor therapy (the leg muscle power training without joint movement: 10 min/a time /a day×4 weeks; the same leg stress training: 10 min/a time /a day×4 weeks), but the latter was done with Ultrashortwave therapy (wave type: continuous wave 100 mA, treating dose: micro heat, 20 min/a time /a day×4 weeks). Then, the clinical symptoms and function activities of being before and after treatment were assessed and managed with statistics. Results: The active and pressed pain of the knee joint in the two group were relieved significantly(P<0.001), but the function improvement of the former surpassed the latter markedly (P<0.001). Conclution: Point injection and motor therapy can not only relieve the pain caused by KOA, but also improve the function activity significantly, and is a new effective therapy for KOA.
摘要:Total 51 fresh adult cadavers(21 male;30 female) were radomly selected.After the locating of acupoints,the cadavers were frozen and then dissected by anatomical sections samples.After defrosting,the distances between the superficial points of the skin and the deep dangerous points were measured and the data were treated statistically.As a result,the safe depths of 70 acupoints were obtained.
摘要:The essence of acupoint and the convergence of acupoint and the primary afferent neurous of viscera at the prospinal cord or in the spinal cord were overvicued,which partly explained the mechanism of the acting specificity of acupoint,the referred pain of viscera and the acupuncture analgesia