最新刊期
卷 ， 期 1 ， 2001
- 摘要：Objective: To determine the fiber type participating in the peripharal information transmission across nerve segments. Methods: Experiments were performed on SD rats anesthetized with intraperitoneal injection of 20% urethane 1 g/kg. The dorsal cutaneous branches of T 9 and T 10 spinal nerves innervating “Ganshu" (BL 18), and “Danshu”(BL 19)of the Pangguang Meridian of Foot Taiyang were freed and cut proximally. The C fiber endings capable of responding to mechanical stimuli were obtained by isolating nerve filaments on the dorsal cutaneous branch of T 10 spinal nerve. Those filaments responding to hair brushing, von Frey's hair pressing were subjected into this study. The dorsal cutaneous nerve of T 9 was antidromically stimulated with single electric pulses. Firing signals were processed with sequential density histograms. Results: It was found that 87.5% (35/40) of the slow adapting units and 50%(5/10) of the fast adapting units of the C fiber endings fired more actively within the first 90 sec after the stimulation, particularly within the first 30 ecs (P<0.001). Slow adapting units and those having a longer after discharge were prone to be activated by electrical stimulation of the adjacent spinal segments. There was no correlation between the spontaneous discharge frequency of unit and its response to the stimulation. Conclusion: These results suggest that the C fibers participate in the information transmission across spinal segments between the peripheral endings, which may contribute to the phenomenon of the sensory conduction along channels.932|0|6更新时间：2023-08-11
- 摘要：Objective: To study the therapeutic effect of electroacupuncture (EA) on alergic shock in guinea pigs. Methods: Experiments were performed on 60 anaphylactic shock model guinea pigs (anesthetized by intra peritoneal injection of pentobarbital sodium 30 mg/kg) who were randomly divided into 60 ～70 Hz plus 1 V (n=7), 30 ～ 40 Hz plus 3 V (n=7) and 30～40 Hz plus 1 V (n=7) groups. The 3 groups were further divided into EA of Neiguan (PC 6) and Non acupoint subgroups. Alergic shock was produced by intra peritoneal and intravenous injection of ovokeratin 10 μg/kg and 0.26～0.28 μg/kg respectively in different days. Mean blood pressure (MAP) was determined via right carotid catheter. Bilateral “Neiguan” (PC 6) were stimulated with frequency 60～70 Hz, 30～40 Hz, voltage 1 V and 3 V and stimulating duration of 30 min. The contents of oxytocin(OT) in hypothalamus,anteropituitary and postpituitary tissues were measured by radioimmunoassay. Results: The results suggested that EA at “Neiguan” point could produce a significant and rapid effect of antianaphylactic shock in comparison with non acupoint group. Under the same frequency, the pressor effect of EA at “Neiguan” point at higher stimulating intensity was significantly better than that of low intensity. Similarly, under the same intensity, the effect of higher frequency was considerably better than that of low frequency in anti anaphylactic action. After EA stimulation at frequency of 30～40 Hz plus voltage of 3 V and 60～70 Hz plus 1 V, OT contents decreased significantly in the hypothalamus and posteropituitay or increased considerably in anteropituitary tissue in comparison with antianaphylactic shock model group (n=7, P< 0.01, 0.05); while after EA at frequency 30～40 Hz plus voltage 1 V, OT contents had slight increase in hypothalamus and postpituitary or slight increase in anteropituitary but without statistical difference in comparison with shock model group. When EA at a fixed frequency (30～40 Hz) or at a fixed stimulating strength (1 V), OT values of voltage 3 V (n=7) and 60～70 Hz groups increased significantly in anteropituitary or decreased significantly in hypothalamus in comparison with voltage of 1 V or 30～40 Hz groups separately (P<0.05). It indicates that the effect of antianaphylactic shock of EA at “Neiguan” point may be mediated by OT. OT seems to be involved in the pressor response by inducing the release of ACTH from anteropituitary under higher intensity EA; while OT released from hypothalamus might be responsible for the pressor response under higher frequency EA.Conclusion: EA possesses a good pressor action in alergic shock guinea pigs, which may be mediated by OT in the hypothalamus.964|0|2更新时间：2023-08-11
- 摘要：Objective:To observe the therapeutic effect of electroacupuncture (EA) on T lymphocyte subgroups of peripheral blood in the rat.Methods: Forty Sprague Dawley rats were divided into five groups: control group, “Zusanli”(ST 36) group, immunosuppressive model group, none point group and immunosuppressive model+ EA group by blocked randomization. Immunosuppressive model was established by intraperitoneal injection of cyclophosphamide 100 mg/kg (twice). Bilateral “Zusanli” (ST 36) were punctured and stimulated with frequency 2 Hz and 3 V for 30 min, once daily, continuously for 7 days. Rats of the immunosuppressive and control group were only fixed to an animal stand for 30 min at the same hours every day. Blood samples were collected on the 7th day after intraperitoneal injection of pentobarbital sodium (1%, 30 mg/kg). The T lymphocyte subgroups of peripheral blood (including CD + 4 and CD + 8) were measured by direct microvolume whole blood immunoflurescent staining technique with flow cytometer(FCM) to evaluate the immune function of rats from different aspects. Results: ① The value of CD + 4 in EA group was significantly higher than that of control group(P<0.01),and the values of CD + 8 between the two groups had no statistical difference, indicating that EA had a markedly regulative effect on the immune function.② The value of CD + 4 in immunosuppressive model group was obviously lower than that of control group(P<0.01)and the values of CD + 8 between the two groups had not any statistical difference (P>0.05),indicating that cyclophosphamidum(CY)restrained the T lymphocyte subgroups of peripheral blood.③ The value of CD + 4 in the immunosuppressive model + EA group was significantly higher than that of immunosuppressive model group(P<0.01).④ The data of the none point group were not different from those of control group(P>0.05). Conclusion: EA on “Zusanli” point can improve cellular immune induced by T lymphocytes, but EA on none point has no such function.1088|0|2更新时间：2023-08-11
- 摘要：Objective: Observing the therapeutic effect of acupoint injection of self blood mixed with gamma globulin on the morphological changes of the pulmonary and bronchial tissues in allergic asthmatic guinea pigs. Methods: 51 guinea pigs were randomly divided into 1) saline intraperitoneal injection group (n=8), 2) asthma model group (n=8), 3) positive drug group (n=7), 4) self blood acupoint injection group (n=7), 5) gamma globulin acupoint injection group (n=7), 6) self blood plus gamma globulin acupoint injection group, and 7) self blood plus gamma globulin intramuscular injection group (n=7). Bilateral Feishu (BL 13) were used for injection. The injection was conducted once daily with 5 sessions being a therapeutic course, two courses altogether. Results: The results showed that the therapeutic effect of the self blood plus gamma globulin is the best, marked by basic disappearance of the muco embolism, no obvious spasm and no thickening of the smooth muscle, considerable alleviation of the inflammatory cell infiltration and disappearance of the bronchial wall congestion and edema under light microscopic observation. The injection of gamma globulin alone also had the above changes, but the effect was moderate. The effect of the self blood injection is also better, being just a little weaker than that of gamma globulin plus self blood injection. Conclusion: Acupoint injection of self blood mixed with gamma globulin has a fairly good therapeutic effect in improving the structural changes of pulmonary and bronchial tissues in asthmatic guinea pigs.906|0|1更新时间：2023-08-11
- 摘要：Objective: To observe the therapeutic effect of transcutanous electric nerve stimulation (TENS) on experimental arthritis in the rat. Methods: Bovine type Ⅱ collagen was intradermally injected into the back of anesthetized rats (with intraperitoneal administration of pentobarbital sodium 30 mg/kg) to induce arthritis,the animal model of rheumatoid arthritis. Bilateral “Zusanli”(ST 36) were stimulated with HANS Therapeutic Apparatus by setting the stimulating parameters being frequency 2 Hz, continuous waves, electric current strength 5 mA and stimulating duration of 30 min. The treatment was given once every other day 10 times altogether. The incidence, arthritic index and serum anti collagen antibody level of collagen and radiological changes of joints were examined. Anti CⅡ antibody levels were determined using enzyme linked immunosorbent assay (ELISA). Results: The results showed that treatment with TENS at “Zusanli” remarkably delayed the onset of arthritis, and significantly relieved the conditions of the diseased limbs and arthritic index in the early and middle stages. But TENS failed to decrease the anti CⅡ antibody levels of immunized rats. Meanwhile, the bone erosion and joint destruction were effectively prevented by TENS treatment.Conclusion: TENS therapy has a better therapeutic effect in relieving the state of experimental arthritis.1082|0|6更新时间：2023-08-11
- 摘要：Objective: To observe the effect of Chinese patent drug “WU JI TIAO JING WAN" (Bolus of Gallus gallus domesticus for Regulating Menstruation) in resisting acupuncture induced contraction of uterine smooth muscle to prevent abortion in rats and mice. Methods:① “Zusanli”(ST 36) was needled with the filiform needle twirled continuously for 10 min, once every 2 min. When the uterine smooth muscle contracted to reach the peak value, the rats were administered (ig) with “WU JI TIAO JING WAN" fluid at a dose of 1.0,4.0 g crude drug/kg, followed by observing changes of uterine smooth muscle again;② When got pregnant, the mice were given with (ig) “WU JI TIAO JING WAN" at a dose of 1.0,2.0,4.0 g crude drug/kg everyday. From the third day on, “Zusanli ”(ST 36) was punctured once everyday and continuously for 10 days. Then the mice were killed for examining the embryonic numbers. Results: When acupuncture stimulation was given, the rat uterine smooth muscle increased significantly in contraction; and the miscarriage mice also increased obviously in number. After administration of “WU JI TIAO JING WAN", the rat uterine smooth muscle relaxed remarkably and the abortion mice decreased in number considerably. Conclusion: “WU JI TIAO JING WAN" can resist acupuncture stimulation induced excitatory contraction of the rat uterine smooth muscle and lower the abortion rate in mice.858|0|2更新时间：2023-08-11
- 摘要：Objective: To observe effects of acupuncture treatment on blood LPO and SOD contents in Parkinsonism patients. Methods: 87 Parkinsonism patients were randomly divided into acupuncture group (n= 59) and medication group (n= 28). Acupoints as Xiaochan point (1.5 cun inferior to Shaohai HT 3), Waiguan (TE 5), Hegu (LI 4), Yanglingquan (GB 34), Taichong (LR 3), Zusanli (ST 36), etc were used and stimulated with uniform reinforcing reducing needling method. The treatment was given once daily, with 10 sessions being a therapeutic course, continuously for 3 courses. Patients in medication group were treated with madopar, sinemet, artane, etc based on the doctor's requirements. Plasma LPO content and SOD content of red blood cells were detected by using thiobarbituric acid via lipid peroxide malonyldialdehyde technique and radioimmunoassay respectively.Results: Results showed that after acupuncture treatment, SOD content increased significantly, particularly in patients above 60 years at age, female patients and the patients with disease duration being less than 3 years in comparison with those under 60 years , male patients and those with disease duration being over 3 years respectively. Conclusion: Acupuncture can function well in preventing Parkinsonism from exacerbation particularly in patients above 60 years old, female patients and those with shorter duration of disease.1088|0|4更新时间：2023-08-11
- 摘要：Objective: To observe the clinical therapeutic effect of acupuncture approach “ Mind Regulation and Meridian collateral Dredging" for the treatment of acute cerebral infarction. Methods: Clinical comparative observations were made by adopting the accumulated scores of nervous functional defect of the patients, 12 degrees limb function evaluation of hemiplegia and daily life activity index. There were 58 cases in treatment group and 40 cases in control group. In treatment group, scalp acupoints used were Dingzhongxian (MS 5), Dingpangxian Ⅱ(MS 9),etc combined with body acupoints Fenchi (GB 20), Binao (LI 14), Quchi (LI 11), Yongquan (KI 1) and Zusanli (ST 36).In control group, Jianyu (LI 15), Quchi (LI 11), Hegu (LI 4), Neiguan (PC 6), Shousanli (LI 10), Yanglingquan (GB 34),etc. The needles in scalp points were manipulated forcefully with lifting and thrusting methods while those in body acupoints were manipulated with uniform reinforcing reducing method after Deqi and retained for 30 min.Results: After the treatment all the indexes of the 2 groups revealed improvement in nerve functional accumulated scores, limb function and daily life index.However, those of the treatment group were significantly better than those of the control group (P< 0.05). Conclusion: The acupuncture approach of “Mind Regulation and Meridian collateral Dredging" can promote the functional restoration of the limbs and better the daily life management ability of the patients in the acute stage of cerebral infraction.903|0|1更新时间：2023-08-11
- 摘要：Objective: To observe the effect of acupuncture combined with analgesics on neoglottis reconstruction operation in 30 cases of pharyngeal tumor patients. Methods: Bilateral Hegu(LI 4) and Futu(ST 32) were punctured and stimulated electrically for 20 min. Adjuvant medicines pethidine (1 mg/kg), rotundin (60 mg) and metoclopramide (10 mg) were used for intramuscular injection 15～25 min before operation, combined with local application (pharyngeal mucosa)of 1% dicaine (12 mL) and neck subcutaneous injection of 0.5% procaine (10 mL). Results: Among the 30 cases, the analgesic effects were class I in 20 cases (the patient had no apparent pain reaction during operation, the operation was conducted smoothly and doses of the above mentioned medicines were within the fixed limit); class Ⅱ in 9 cases (the patient experienced slight pain, pethidine was increased in dose (1.5 mg/kg) and the operation could be accomplished smoothly); and class Ⅳ in one case (the patient experienced unbearable pain during operation and the operation could not carried out). The successful rate was 96.7%.Conclusion: Under acupuncture anesthesia combined with analgesics, the neoglottis reconstruction operation achieved a satisfactory result.758|0|0更新时间：2023-08-11
- 摘要：Objective: To observe the clinical effect of acupuncture anethesia in combination with general anesthesia of enflurane for radical operation of esophageal carcinoma. Methods:Single blind test has been adopted and 120 cases were divided at random into 3 groups, i.e. A, B, C. Group A (n=40): acupuncture integrated with general anesthesia of enflurane inhalation. Group B (n=41): acupoint stimulation with plate electrode combined with general anesthesia of enflurane inhalation. Group C (n=39): simple inhalation general anesthesia (control group). Acupoints used were Yifeng (TE 17), Sanyangluo (TE 8) to Ximen (PC 4) and Xiayifeng and were stimulated with electric current 2～ 4 mA, frequency 2/15 Hz and intermittent dense sparse waves in Group A. Sanyangluo (TE 8) and Xiayifeng were stimulated with 10～13 mA via skin electrodes. For anesthesia induction all the 3 groups received same dose of intravenous injection of vecuromine, fentanyl and isophorone. During the operation all the groups received intravenous injection of fentany (2 μg·kg -1 ·hr -1 ), and vecuromine (0.03 mg·kg -1 ·0.5 hr -1 ), and inhaled the enflurane of appropriate concentration to maintain anesthesia and muscular relaxation according to the requirements for anesthesia. In group A and Group B the electric stimulation were used at the same time.Results: In Group A and Group B the rate of anesthesia grade I is 67.50% and 68.29% respectively, whereas in group C the rate of Grade I is merely 28.21%,P<0.001; In the whole process of anesthesia the average concentration of enflurane in Group A and Group B was 0.55% and 0.50% respectively, but in Group C it was 0.83%. The inhaled enflurane concentration in Group A and Group B is 33.73% and 39.76% respectively being strikingly lower than that of Group C (P<0.005).Conclusion:Acupuncture combined with general anesthesia of enflurane inhalation can not only enhance the analgesic effect, but also reduce the inhalation dosage of enflurane, it reveals the advantage of acupuncture anesthesia, thus, being applicable in the clinic.1003|0|3更新时间：2023-08-11
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- 摘要：Objective:To observe the effect of peripheral norepinephrine (NE) level on acupuncture analgesia.Methods:33 cases of cholecystectomy patients were randomly divided into group A (acupuncture combined with extradural-T 4～12 administration of small dose of analgesic, lidocaine 1.5%, 4 mL),group B (electrical stimulation of acupoint skin via cutaneous electrodes combined with extradural administration of small dose of analgesic)and group C (control group, only extradural administration of small dose of analgesic). Each group contained 11 cases respectively. The plasma NE,epinephrine(E) and dopamine (DA) concentrations were determined on the day before operation, during operation (30 minutes after anesthesia) and 3 days after operation in all the cases using high pressure liquid chromatography (HPLC)-electrochemical technique.Bilateral Zusanli (ST 36) and Neiguan (PC 6) were used and stimulated electrically with frequency 2/15 Hz, intermittent waves, and 2 ～ 3 mA for group A and 13 mA for group B.Results: The results showed that in group A and B,the plasma NE concentrations reduced respectively from 3.85±1.47 ng/mL and 2.90±1.49 ng/mL of pre operation to 2.28±0.84 ng/mL and 2.34± 1.57 ng/mL during operation. There were significant differences between pre and post operation in NE level in both groups (P<0.01).While in group C,the NE level increased from 2.73±1.26 ng/mL to 2.89±1.46 ng/mL during operation.The contents of plasma E in group A, B and C increased obviously and respectively from 2.33±0.58 ng/mL , 1.74±1.22 ng/mL and 1.85±0.77 ng/mL of pre operation up to 3.67±1.39 ng/mL , 3.19±1.92 ng/mL and 2.51±1.62 ng/mL during operation (P<0.01). The plasma DA contents in the 3 groups also increased during operation.All the values of plasma NE,E and DA on the 3rd day after operation in the 3 groups were close to the basic levels of pre operation.It indicates that either acupuncture or acupoint superficial electrical stimulation combined with extradural anesthesia assumes a suppressive action on the activity of sympathetic nerve during surgical operation. The effect of acupuncture analgesia is mainly related to the plasma NE level rather than plasma E and DA.The lower the plasma NE level (group A and B),the better is the analgesic effect. Conclusion: Acupuncture and acupoint surface electrical stimulation combined with extradural administration of small dose of analgesic may be capable of inhibiting the stress response caused by surgical operation in the human body.892|0|3更新时间：2023-08-11
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- 摘要：Objective: To observe the effect of granule moxibustion on saliva amylase activity and the Serum SIgA. Methods: One hundred and twelve diarrhea patients were randomly divided into treatment group (n= 56) and control group (n= 56). Patients of treatment group were treated by granule moxibustion over Pishu (BL 20), Weishu (BL 21) and Zusanli (ST 36), once every other day, three cones per point, continuously for 30 days. Fifty six cases in control group were treated with Chinese herbal medicine (Shenling Baizhu Powder Powder of Ginseng, Poria and Bighead Atractylodes, 6 g/time, 3 times/day, continuously for one month). Results: Granule moxibustion could obviously improve the clinical symptoms (P<0.05～P～0.001) and increase saliva amylase activity (P<0.001) , while decrease Serum SIgA (P<0.05). The therapeutic effect of acupuncture was superior to that of Chinese herbal medicine (P<0.01,P<0.05). Conclusion: Granule moxibustion over Pishu (BL 20) etc has a definite beneficial action on spleen deficiency type diarrhea.1004|0|1更新时间：2023-08-11
- 摘要：Objective: To observe the therapeutic effect of application of herbal paste to Shenque (CV 8) for treatment of infantile upper respiratory tract infection. Methods: 142 cases of infantile upper respiratory tract infection were subjected into this study. Herbal paste Formula I processed from Huangqin (Radix Scutellariae) and Gancao (Radix Glycyrrhizae) and Formula Ⅱ processed from Huangqi (Radix Astragali seu Hedysari), Baizhu (Rhizoma Atractylodis Macrocephalae), etc were applied to Shenque (CV 8) respectively for the pattern of invasion of the lung Wei by exogenous pathogenic factors and the pattern of deficiency of the spleen Qi. The former pattern was attributed to acute stage of the upper respiratory tract infection and the latter to the remission stage after the symptoms of the acute stage being under control. Before fixing the drug paste, the local umbilicus was radiated with TDP lamp for 20 min. 12～16 hours later the drug paste was removed. This treatment was conducted twice every week, with 8 sessions being a therapeutic course. Results: After 2 courses of treatment, of the 142 cases, 36 (25.3%) were cured, 46 (32.4%) had marked improvement, 47 (33.1%) had improvement and 13 (9.1%) had no significant effect. The total effective rate was 90.8%. Conclusion: The topical application of the medicinal paste at Shenque (CV 8) has a better therapeutic effect in treatment of infantile upper respiratory tract infection and is worth of popularizing.978|0|2更新时间：2023-08-11
- 摘要：Objective: To observe the therapeutic effect of acupuncture in treatment of herpes zoster. Methods: A total of 38 cases of herpes zoster patients including 16 males and 22 females were subjected into the present observation. The shortest duration of disease was 2 days and the longest 11 days. The focal regions involved chest, back, neck and face. After routine sterilization, the bilateral thumb joint acupoints were punctured with a three edged needle and squeezed to let about 2～3 drops of blood out. Filiform needles were separately inserted into the surrounding tissues of the focus region, with the needle tips towards the central part of the focus. The distance between every two needles was about 3～ 4 cm . The needles were manipulated gently and retained for 30～60 min. Results: Following 20 sessions of acupuncture treatment, of the 38 cases, 31 (81.6%) were cured and 7 (18.4%) had marked amelioration. Conclusion: Acupuncture of thumb joint acupoint with focal enclosing needling has a good therapeutic effect in treatment of herpes zoster.714|0|0更新时间：2023-08-11
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- 摘要：In the present paper, the author summarized the recent advances (from 1996 on) in experimental research on of anti cerebral aging of acupuncture and moxibustion from 1) regulative action of acupuncture on neuro endocrine system, memory, excitatory amino acid metabolism, cellular histone, apotosis, etc; 2) regulative action of moxibustion on neuro endocrine functional activity, etc; and 3) the effects of other therapies. The author holds that up to now, acupuncture and moxibustion therapies have a certain action in resisting aging, but the acupoint recipes, therapeutic methods and indexes for assessing the therapeutic effect, etc used at the present have no united standards.968|0|3更新时间：2023-08-11
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