最新刊期
卷 ， 期 1 ， 2007
- 摘要：Objective:To study the scientific basis of specific correlation between the meridian and the Zang-or Fu-organ by using gene differential expression(gene-chip technique)in the rat.Methods:Twenty-one SD rats were randomly and evenly divided into control group,sham-myocardial ischemia(MI)group,MI group,electroacupuncture(EA)-Heart-Meridian(HT)group,EA-Lung-Meridian(LU)group and EA-Small-Intestine-Meridian(SI)group.EA(frequency 2 Hz,stimulating strength 5 V,pulse duration 300 μs)was applied to “Shenmen”(HT 7)-“Tongli”(HT 5)(Heart Meridian),“Yanglao”(SI 6)-“Zhizheng”(SI 7)(Small Intestine Meridian),“Taiyuan”(LU 9)-“Lieque”(LU 7)(Lung Meridian)for 20 min,once daily and continuously for 3 days.Myocardial ischemia model was duplicated by occlusion of the anterior descending branch of the left coronary artery,and myocardial tissue of the left ventricle was taken 3 days after EA treatment for analyzing the differentially expressed genes in different groups with rat whole gene U 230 sequence chips(offered by Affymetrix Company).Results:Compared with model group,among the differentially expressed genes being twofolds and above,the up-regulated and the down-regulated were 20 and 70 in EA-HT group,18 and 26 in EA-SI group,and 14 and 20 in EA-LU group separately.Few same genes with the same differential expression were found among the 3 EA groups.Conclusion:There is exactly a molecular basis in the correlation between Heart Meridian and the heart,and EA of Heart Meridian,Small Intestine Meridian and Lung Meridian have their own special signaling pathways.关键词：Correlation between meridians and Zangfu-organs;Gene chips;Differentially expressed genes;Myocardial ischemia;Electroacupuncture1181|0|7更新时间：2023-08-11
- 摘要：Objective:To study the effects of electroacupuncture(EA)on the immunoreactivity of focal cutaneous cannabinoid receptor 2(CB2)positive cells in adjuvant arthritis(AA)rats.Methods:A total of 48 adult female SD rats were randomly divided into control group(n=12),model group(n=12),acupoint group(n=12),and non-acupoint group(n=12).Arthritis model was established by hypodermic injection of complete Freund's adjuvant(CFA,50 μL)into the left ankle joint.EA(2/15 Hz,1 mA)was applied to “Huantiao”(GB 30)and “Yanglingquan”(GB 34)or two control points 5 mm left to GB30 and GB34 on the diseased side for 30 min,once every other day from the second day on after injection of CFA.Behavioral performance(pain test score)was assesed by using dorsiflexion and plantarflexion pain tests.On the 6th and 16th day after injection of CAF,the animals were anesthetized with 20% urethane(1 g/kg)for collecting the focal skin and subcutaneous tissue samples which were cut into sections(5 μm)to be stained with HE(haematoxylin & cosin)method and immunohistochemical technique respectively for observing changes of the focal cells of the inflamatory tissue and the immunoactivity of the focal cutaneous CB receptor positive cells.Results:1)In comparison with control group,the scores of both dorsiflexion and plantarflexion pain tests in mod-el,acupoint and non-acupoint groups increased evidently after modeling(P<0.05).Compared with model group,the scores of dorsiflexion test on the 3rd day and 5th day and plantarflexion test on the 5th day in EA-acupoint group were considerably lower(P<0.05),and the scores of the two tests on the 3rd day and 5th day of acupoint group were also markedly lower than those of non-acupoint group(P<0.05),suggesting a marked pain-relief after EA;while no significant differences were found between non-acupoint and model groups.2)HE staining showed that the inflammatory cells in the dermal layer of the focus of acupoint group were evidently fewer than those of model and non-acupoint groups on the 6th day and 16th day after modeling.3)The immunohistochemical results revealed that compared with control group,on the 6th day,the percentages of CB2 receptor positive cell area in the focus of model,non-acupoint and acupoint groups were significantly higher(P<0.05),and that of acupoint group was markedly higher than those of model and non-acupoint groups(P<0.05),suggesting further upregulation of the expression of CB2 receptor positive cells;no significant differences of percentages of CB2 receptor immunoreaction positive cell area among model,non-acupoint and acupoint groups were found on the 16th day(P>0.05).Conclusion:EA of GB30 and GB34 can raise the immunoactivity of cutaneous CB2 receptor positive cells in the inflammatory tissue which maybe contribute to its effects in relieving inflammatory pain and suppressing focal inflammation and adjusting the balance of nociception and antinociception in AA rats.关键词：Adjuvant arthritis;Electroacupuncture;Cutaneous cannabinoid receptor 2(CB2)expression;Pain test;HE staining1202|0|4更新时间：2023-08-11
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Relationship Between the Function of Mast Cells and Acupuncture Analgesia in Adjuvant Arthritis Rats
摘要：Objective:To investigate the relationship between mast cell degranulation and acupuncture analgesia.Methods:A total of 58 SD male rats were randomly divided into control(n=12),model(n=12),needle-retaining(n=12),electroacupuncture(EA,n=12)and manual-acupuncture(MA,n=10)groups.Arthritis model was established by injection of complete Freund's adjuvant(0.05 mL)into the left ankle-joint.The paw withdrawal latency(PWL)was detected with a radiant heat algesimeter.Electroacupuncture(EA,2/100 Hz,0.5-1.5 mA)or manual acupuncture(lifting and thrusting force being 240-280 mN,torque being 10-15 mN·mm,3 times/s)were applied to “Zusanli”(ST 36)on the affected side for 30 min in the corresponding group.After decapitation(under anesthesia),skin tissue around the stimulated ST36 was sampled,cut into sections(5 μm),and stained with Toluidine Blue for observing the count of degranulated mast cells.Results:In comparison with control group,PWL values of model,needle-retaining,EA and MA groups decreased significantly after modeling(P<0.01);while compared with needle-retaining group,PWL values of EA and MA group increased considerably(P<0.01),suggesting production of analgesia.After EA and MA stimulation,degranulation of mast cells in the stimulated ST36 area appeared apparently.Compared with needle-retaining group,the degranulation ratios of mast cells in EA and MA groups were obviously higher(P<0.01).Conclusion:Both EA and MA stimulation of “Zusanli”(ST 36)can effectively raise pain threshold,simultaneously,and enhance the degranulation ratio of mast cells in the stimulated ST36 area.关键词：Acupoint;Mast cells;Degranulation ratio;Acupuncture analgesia1182|0|18更新时间：2023-08-11 -
CGRP May Take Part in the Effect of Electroacupuncture in Resisting Acute Myocardial Ischemic Injury
摘要：Objective:To probe into the relationship between “Xinshu”(BL 15)-“Jueyinshu”(BL 14)of the Bladder Channel and the heart and the underlying mechanism of electroacupuncture(EA)in resisting acute myocardial ischemia(AMI)in rats.Methods:A total of 24 male Wistar rats were randomly divided into control,model and EA groups with 8 cases in each group.AMI model was duplicated by intraperitoneal injection of 2% isoproterenol(ISO,100 mg/kg).EA(pulse duration 300 μs,frequency 2-20 Hz,output voltage 3.5-5 V)was applied to BL14 and BL15 on the left side for 30 min,twice in a day(with an interval of 12 h).After decapitation,blood samples,myocardial tissue and spinal cord(T1-T6)were collected respectively for detecting serum creatine kinase(CK,with chromatometry)and calcitonin gene-related peptide(CGRP)contents in the plasma,myocardium and the spinal cord(with radioimmunoassay).Results:In comparison with control group,serum CK of both model group and EA group increased significantly(P<0.01),and plasma CGRP content of model group lowered lightly;while compared with model group,CK content of EA group decreased obviously(P<0.05)and plasma CGRP of EA group increased evidently(P<0.05).No significant differences were found among 3 groups in myocardial CGRP contents and between control group and model group in spinal CGRP contents(P>0.05).Conclusion:EA of “Xinshu”(BL 15)-“Jueyinshu”(BL 14)may suppress isoproterenol-injection induced myocardial injury and plasma CGRP possibly takes part in the protective effect of EA in resisting myocardial ischemia injury.关键词：Ischemia myocardical injury;Electroacupuncture;CK;CGRP1118|0|0更新时间：2023-08-11 - 摘要：Objective:To observe the effect of electroacupuncture(EA)on serum lipid and cerebral neurogrowth factor(NGF)in rats with hyperlipemia and cerebral ischemia(CI).Methods:A total of 36 SD rats were evenly randomized into control,model,EA-Ⅰ and EA-Ⅱ groups with 9 cases in each group.Hyperlipemia plus CI model was established by feeding the rats with high-fat foodstuff(6 weeks)and FeCl3-evoked middle-cerebral-artery(MCA)occlusion method.EA(15 Hz,1-3 mA)was applied to “Sanyinjiao”(SP 6)and “Fenglong”(ST 40)for 20 min,once daily,continuously for 7 days,additionally,“Baihui”(GV 20)and “Shuigou”(GV 26)were punctured and stimulated with hand,which was conducted first before MCA occlusion for rats of group EA-Ⅰ and after MCA occlusion for rats of group EA-Ⅱ separately.Fasting blood samples(2 mL/rat)were taken for detecting serum total cholesterol(TC),triglyceride(TG),low density lipid cholesterol(LDL-C)and high density lipid cholesterol(HDL-C)levels.After decapitation of the rats,cerebral tissues were taken,homogenated for detecting NGF content with ABC-ELISA(enzyme-linked immunosorbent assay)and some other cerebral tissues were cut into sections(6 μm)for observing structural changes of the brain after staining with haematoxylin and cosin(HE)method.Results:Compared with control group,serum TC,TG and LDL-C contents of model,EA-Ⅰ and EA-Ⅱ groups increased significantly on day 42 and 59 after modeling(P<0.01),and HDL-C content of model,EA-Ⅰ and EA-Ⅱ groups decreased markedly on day 42 after modeling(P<0.01).Compared with model group,TC contents of both EA-Ⅰ and EA-Ⅱ groups,and TG and LDL-C of EA-Ⅰ group decreased significantly on day 59 after establishing the model(P<0.05,0.01).No significant differences were found between EA-Ⅰ and EA-Ⅱ groups in the 4 indexes of blood lipid(P>0.05).HE staining showed that in model group,neuronal ischemic injury including cellular swelling,edema and nuclear fragmentation in the striatum and the cortex of parietal lobe,widening of the cellular interspace,vacuolation,irregularity of the kytoplasm and karyolemma,etc in CA3 region of hippocampus was apparent,while the situation in EA groups was lighter.Regarding the changes of NGF,compared with control group,NGF contents of model group and EA-Ⅱ group were significantly lower(P<0.01);while compared with model group,NGF content of EA-Ⅰ was significantly higher(P<0.01);and that of EA-Ⅱ group was markedly lower than that of EA-Ⅰ group(P<0.05).Conclusion:EA can lower the levels of serum TC,LDL-C and TG and suppress cerebral ischemia plus hyperlipemia induced decrease of NGF level in the brain,which may contribute to its effect in relieving ischemic cerebral injury.关键词：Hyperlipemia with cerebral ischemia;Acupuncture therapy;Plasma lipid;Cerebral NGF1184|0|16更新时间：2023-08-11
- 摘要：Objective:To observe the effects of “Warmth-producing Needling for Removing Obstruction”(WPNRO)on the pathomorphological changes of brain and learning-memory abilities in vascular dementia(VD)rats.Methods:A total of 50 Wistar rats were randomly divided into normal control,model,medication,needle-twirling,and WPNRO groups,with 10 cases in each group.VD model was established by repeated cerebral ischemia-reperfusion via repeated occlusion of the bilateral common carotid arteries under anesthesia(3% embutal 40 mg/kg,i.p.).“Dazhui”(GV 14),“Baihui”(GV 20)and “Shuigou”(GV 26)were punctured with filiform needles and stimulated with twirling technique and WPNRO technique respectively and continuously for 1 min.Animals of medication group were fed with Nimodipine(0.0108 g/kg).The treatment was conducted once daily continuously for 15 days.The rats' learning and memory results were detected respectively with step-down avoidance test in the first 6 days' training and 24 h later.At the end of experiments and after decapitation,the right brain was taken,cut into sections(5 μm)and stained with H & E method for observing structural changes of hippocampus.Results:1)Behavior reactions:compared with control group,the latency for finding the safe platform and the times of error in model group increased significantly,and compared with model group,both latencies and times of error in WPNRO,needle-twirling and medication groups decreased considerably(P<0.05,0.01).In comparison with needle-twirling group,both latencies and times of error in WPNRO group were significantly fewer(P<0.05,0.01),and no significant differences were found between WPNRO and medication groups in these two indexes(P>0.05).It indicated that acupuncture particularly WPNRO could improve both learning and memory abilities in VD rats.2)Structural changes of neurons in CA1 region of hippocampus:in normal group,the neurons arranged in order and closely,and were normal in the structure;in model group,the neurons arranged obviously in disorder,had karyopyknosis and hyperplasia in glial cells and decreased in the number.In WPNRO group,no evident cellular karyopyknosis or hyperplasia of glial cells was found,and the structure and number of cells were close to those of normal group.In acupuncture and medication groups,fewer neurons,cellular karyopyknosis and hyperplasia of more glial cells were found.Conclusion:“Warming-producing Needling for Removing Obstruction” can significantly relieve cerebral ischemia induced disturbance of learning and memory and lessen structural injury of hippocampal neurons in rats.关键词：Vascular dementia;“Warming-producing Needling for Removing Obstruction”;Hippocampus;Pathomorphological changes;Learning and memory1152|0|5更新时间：2023-08-11
- 摘要：Objective:To observe the relationship between changes of interleukin-1β(IL-1β)and tumornecrosis factor-α(TNF-α)contents in the hippocampus and learning-memory ability in vascular dementia(VD)rats and the interventional effect of electroacupuncture(EA)on the contents of IL-1β and TNF-α.Methods:SD rats were randomized into control group(n=10),model group(n=11)and EA group(n=12).VD model was established by using Pulsinelli's 4-vessel occlusion(4-VO)technique.EA(2 mA,50 Hz)was applied to “Baihui”(GV 20)and “Dazhui”(GV 14)for 20 min,once a day and continuously for 15 days.The rats' learning-memory abilities were tested by Morris water-maze(place navigation test and special probe test)continuously for 6 days,and then the rats were sacrificed for taking hippocampus tissue which was homogenized for detecting IL-1β and TNF-α contents by using radioimmunoassay(RIA)technique.Results:Place navigation test and special probe test showed that compared with control group,the mean escape latencies and the times of crossing the original platform quadrant in model group and EA group were significantly longer and more(P<0.01).Comparison between model group and EA group indicated that the escape latency of the later group was markedly shorter than that of the former group(P<0.05),no significant differences were found between EA group and control group in the staying duration in the original platform quadrant(P>0.05),suggesting an improvement of learning-memory abilities after EA.In comparison with control group,both IL-1β and TNF-α contents in the hippocampus tissue were significantly higher in model group and EA group(P<0.05,0.01),and those of EA group were considerably lower than those of model group(P<0.01).Conclusion:EA can improve VD rats' learning-memory abilities,which is closely associated with its effects in suppressing VD-induced increase of IL-1β and TNF-α levels in the hippocampus.关键词：Vascular dementia;Electroacupuncture;Learning-memory abilities;Interleukin-1β;Tumor necrosis factor-α1161|0|2更新时间：2023-08-11
- 摘要：Objective:To observe the effect of electroacupuncture(EA)on plasma estrin(E)2 and bone mineral density(BMD)in ovariectomized(OVX)rats for studying its underlying mechanism in treating osteoporosis.Methods:Thirty-two female SD rats were randomized into normal control,model,EA,and medication groups with 8 rats in each group.Postmenopausal osteoporosis model was established by removing the uterus under anesthesia(2% Phenobarbital,40 mg/kg).In EA group,bilateral “Zusanli”(ST 32)and “Sanyinjiao”(SP 6)were punctured and stimulated electrically for 20 minutes with 1-3 Hz in frequency,1 ms in duration of waves,and 0.7-1.0 mA in strength,once daily and 8 weeks altogether.Rats of medication group were drenched with 5% Nilestriol,5 mL/week and for 8 weeks.At the end of experiments,blood samples were collected after removing the rat eyeball,and the left femoral bone tissue was taken.Serum E2 was assayed by using enzyme linked immunosorbent assay(ELISA)and BMD was measured by using double functional X-ray digital bone density meter.Results:Compared with normal group,the body weight of model group was significantly bigger(P<0.05),and that of model group was also significantly bigger than that of EA and medication groups(P<0.01).No significant differences were found among the 4 groups before experiments and among normal control and EA groups after treatment(P>0.05).In comparison with normal group,BMD and serum E2 of model group decreased significantly(P<0.01),while compared with model group,BMD and E2 of EA and medication groups increased significantly(P<0.01,<0.05).No significant differences were found among normal,EA and medication groups(P>0.05).Conclusion:Both EA and medication can increase BMD and serum E2 in OVX rats,which may be one of the mechanisms of acupuncture in treating osteoporosis.关键词：Osteoporosis;Electrocupuncture;Bone mineral density;Estrin 2;Body weight1101|0|15更新时间：2023-08-11
- 摘要：Objective:To observe the underlying mechanism of acupuncture technique for ventilating the lung,invigorating the spleen and tonifying the kidney in the treatment of bronchial asthma(or asthma for short).Methods:According to the severity of the disease during the persistent stage and paracmasis,71 outpatients and inpatients were randomized into treatment group(n=40)and control group(n=31).Patients of treatment group were treated with acupuncture of Quchi(LI 11),Lieque(LU 7),Yuji(LU 10),Neiguan(PC 6),Zusanli(ST 36),Sanyinjiao(SP 6),Taixi(KI 3),etc.,once daily and those of control group treated with anti-asthma drugs as Cromolyn sodium,Albuterol,fenoterol,etc.Before and after 12 days of the treatment,heart rate variability(HRV)and pulmonary function were detected respectively.Results:In paracmasis and mild type asthma patients,self-comparison indicated that after the treatment,total power(TP),very low frequency(VLF),triangular index(TI)and the percentage of the adjacent R-R intervals(PNN50)of HRV,and forced expiratory volume in the first second(FEV1)(%PRED),forced expiratory flow(FEF)0.2-1.2(L/s),FEF75%-85%(L/s),peak expiratory flow(PEF)(%PRED),FEF25%(%PRED)in treatment group increased significantly(P<0.05,0.01),while no significant changes of various components of both HRV and pulmonary function were found in control group(P>0.05).Comparison between two groups showed that after the treatment,the values of TP,VLF,TI and PNN50 of HRV,and FVC(%PRED),FEV1(%PRED),FEV1/FVC(%PRED),FEF0.2-1.2,FEF25%-75%,PEF(%PRED)and FEF25%(%PRED)in treatment group were significantly higher than those in control group(P<0.05).In moderate and severe type asthma patients,self-comparison showed that after the treatment,TP,LF,LFnorm,VLF,LF/HF,VLF/HF,(LF+VLF)/HF,TI and PNN50 of HRV,and FVC(%PRED),FEV1(%PRED),FEV1/FVC(%PRED),FEF0.2-1.2,FEF25%-75%(%PRED),FEF75%-85%,PEF(%PRED),FEF25%(%PRED),FEF50%(%PRED and FEF75%(%PRED)of the pulmonary function all increased remarkably(P<0.05,0.01,0.001);while in comparison with control group,LF,LFnorm,VLF,(LF+VLF)/HF and TI of HRV,and all the parameters of the pulmonary function except FEV1/FVC were significantly higher than those in control group(P<0.05,0.01,0.001).No significant changes of various components of both HRV and pulmonary function were found in control group(P>0.05).Conclusion:Acupuncture is significantly superior to medication in improving the pulmonary function of asthma patients with different state of disease,which is related to its function in regulating activities of the autonomic nervous system.关键词：Acupuncture therapy;Bronchial asthma;Heart rate variability;Pulmonary function949|0|5更新时间：2023-08-11
- 摘要：Objective:To investigate the underlying mechanism of acupoint-catgut-embedding in the treatment of simple obesity.Methods:Eighty simple obesity patients were randomly and evenly divided into acupoint-catgut-embedding group and acupuncture group according to the random number table method.Main acupoints selected on the basis of differentiation of symptoms and signs were Liangqiu(ST 34),Zhongwan(CV 12),Tianshu(ST 25),Shuifen(CV 9),Fenglong(ST 40)and Ashi-point.Catgut embedding was performed once a week,with 4 weeks being a therapeutic course.Acupuncture was given once daily in the 1st 5 days,and once every other day thereafter.Before and after the treatment,body weight(BW)and body mass index(BMI)were detected;fasting blood samples were collected from the ulnar vein for detecting insulin(FINS)and glucose(FBG)contents,and tumor necrosis factor(TNF)-α concentration with enzyme-linked immunosorbent assay(ELISA);and insulin resistance index(IR)was calculated by using Homeostasis Model Assessment(HOMA).Results:Compared with control group,values of BW,BMI,serum FINS,serum FBG,serum TNF-α contents and HOMA-IR of acupoint-catgut-embedding and acupuncture groups were significantly higher(P<0.01)before the treatment.Compared with pretreatment,BW,BMI,FINS,HOMA-IR and TNF-α of both acupoint-catgut-embedding and acupuncture groups decreased significantly after one course of treatment(P<0.05,0.01),but no significant differences were found between these two groups in these 6 indexes(P>0.05).After the treatment,of the two 40 cases in acupuncture and acupoint-catgut-embedding groups,12 and 13 were cured,13 and 15 had a marked improvement,10 and 8 had an improvement,5 and 4 failed,with the effective rates being 87.5% and 90.0% respectively.No significant difference was found between two groups in the effective rate(P>0.05).Conclusion:Both acupoint-catgut-embedding and acupuncture have a definite therapeutic effect in the treatment of simple obesity,which is closely associated with the decline of serum insulin,glucose and TNF-α levels,and the decrease of insulin resistance.关键词：Simple obesity;Acupoint-catgut-embedding;Acupuncture;Tumor necrosis factor-α;Insulin resistance1196|0|5更新时间：2023-08-11
- 关键词：Bronchial asthma;Medicinal vesiculation therapy;IgE;LTR;Eosinophile granulocyte;Time-effectrelationship1032|0|1更新时间：2023-08-11
- 摘要：Objective:To observe the therapeutic effect of “Xingnao Kaiqiao Zhenfa”(Acupuncture Technique for Restoring Consciousness)in the treatment of post-stroke depression.Methods:A total of 256 stroke patients were divided into acupuncture group(n=180,male 138,female 42)and medication group(n=76,male 57 and female 19)according to their visiting sequence to our hospital.Acupoints used were Neiguan(PC 6),Renzhong(GV 26),Baihui(GV 20),Yintang(EX-HN 3)and Sanyinjiao(SP 6,the affected side)and the needles were retained for 20 min every time.Patients of medication group were asked to take Amitriptyline(50 mg/d at first,200 mg/d).Acupuncture treatment was conducted twice daily,and after one month's treatment the therapeutic effect was evaluated.Self-Rating Depression Scale(SDS)and Hamilton Rating Scale for Depression(HRSD)were used to assess the patient's state of depression.Results:After the treatment,of the 180 and 76 cases in acupuncture and medication groups,31(17.2%)and 13(17.1%)were cured,73(40.6%)and 18(23.7%)had a marked improvement in their depression state,27(15.0%)and 12(15.8%)had an improvement,49(27.2%)and 33(43.4%)failed,with the effective rates being 72.8% and 56.6% respectively.The markedly effective rate and the total effective rate of acupuncture group were significantly higher than those of medication group(P<0.05).After the treatment,the total scores of SDS and HRSD and the severity index of two groups decreased pronouncedly in comparison with those of their individual pre-treatment;and the therapeutic effects of acupuncture group were significantly better than those of medication group in reducing SDS,HRSD and severity index(P<0.05).In addition,the decreased values of depression,pessimistic mood and irritability of acupuncture group were all bigger than those of medication group(P<0.05).No significant difference was found between two groups in the decreased value of insomnia(P>0.05).Conclusion:“Acupuncture Technique for Restoring Consciousness” can effectively improve depression patients' symptoms and the therapeutic effect of acupuncture is markedly superior to that of medication for post-stroke patients.关键词：Post-stroke depression;Acupuncture technique for restoring consciousness;Medication1078|0|3更新时间：2023-08-11
- 摘要：Objective:To observe the channel state in patients with acute sport injury of external malleolus joint from the cutaneous electrical conductance quantity(ECQ)of Jing(Well)-points,Yuan(Source)-points and Luo(Collateral)-points of the twelve regular channels.Methods:Forty-five patients with acute sport injury of external malleolus joint were chosen to be used as the observation group,and 30 healthy people as the control group.The ECQ of the cutaneous tissue of Jing-points,Yuan-points and Luo-points of the twelve regular channels was detected by using HB-DET Acupoint Diagnosis-Therapeutic Apparatus under room temperature.If the difference of ECQ values between the bilateral limbs exceeded 50%,it was considered to be imbalance.Results:In observation group,the imbalance state reflected from ECQ of Jing-points mainly involved Trienergizer Channel of Hand-Shaoyang and the Kidney Channel of Foot-Shaoyin,with the imbalance rate being 60.0%(27/45)and 55.6%(25/45)respectively which were significantly higher than those [0 and 3.3%(1/30)] of control group(P<0.05).The ECQ of the Yuan-points of the 12 regular channels indicated that the imbalance state mainly involved the Bladder Channel(32/45,71.1%),Gallbladder Channel(30/45,66.7%),Liver Channel(28/45,62.2%),Kidney Channel(27/45,60.0%),Stomach Channel(25/45,55.6%)and Pericardium Channel(21/45,46.7%)which were significantly higher than those [1/30(3.3%),0,1/30(3.3%),0,0,and 0] of control group in the number of imbalanced channels(P<0.05).The ECQ of the 12 Luo-points showed that the imbalanced channels were mainly Gallbladder Channel(29/45,64.4%)and Bladder Channel(29/45,64.4%)which were significantly higher than those [0,and 1/30(3.3%)] of control group in the number(P<0.05).Of the 540 Jing-points,540 Yuan-points and 540 Luo-points,93(17.2%),181(33.5%)and 96(17.8%)appeared imbalance,and the imbalance rate of Yuan-points was apparently higher than those of Jing-points and Luo-points(P<0.05).Conclusion:Acute sport injury of external malleolus joint may lead to imbalance of channels passing through the injured areas,and also involves the channel(Pericardium Channel)dominated by the heart and the 12 Yuan-points.849|0|0更新时间：2023-08-11
- 摘要：From the angle of clinical study methodology,the authors of the present paper sum up the related articles on acupuncture treatment of dysphagia caused by ischemic stroke published in the past decade from 1)randomized control trials,2)non-controlled observation on a group of cases,and 3)case report.The authors point out some defects as lack of description on the random method,lack of united standards for acupoint recipes,acupuncture-needle manipulations,duration of treatment,united and authorized standards for assessing the therapeutic effect,intent-to-treat analysis,etc in the current clinical studies on acupuncture treatment of apoplectic dysphagia,and thus,the rationality and reliability of conclusions about the therapeutic effects of acupuncture for apoplectic dysphagia in many articles are limited.In order to further confirm the effectiveness of acupuncture for dysphagia resulting from ischemic stroke and to provide enough and reliable clinical evidence,it is necessary to adopt the principles and methods of evidence-based medicine to improve our clinical trials and particularly to look for the best model favoring the development of acu-moxibustion study in the coming days.关键词：Apoplectic dysphagia;Acupuncture therapy;Clinical trials;Methodology1101|0|5更新时间：2023-08-11
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