最新刊期
卷 ， 期 5 ， 2007
- 摘要：Objective: To observe the influence of acupuncture on the immune function in immunosuppressive Cx43 knockout mice so as to explore the relationship between connexin 43(Cx43) and acupuncture signal transmission.Methods: Eighteen male Cx43 knockout mice(Cx43+/-,8-9 weeks old) and eighteen wide-type mice(Cx43+/+) were divided into normal group,model group and acupuncture group randomly,with 6 cases in each.The immunosuppressive mice model was established by intraperitoneal injection of Cyclophosphamide.Mice in acupuncture group were treated with manual acupuncture of "Zusanli"(ST 36) and "Guanyuan"(CV 4),once daily for 7 days.Spleen index,thymus index,number of leukocytes in the peripheral blood were calculated and the percentage of T lymphocyte subpopulation was detected by using flow cytometry.Results: Compared with normal control group,the spleen index,thymus index and leukocyte number of model group in both Cx43+/+mice and Cx43+/-mice were obviously lower(P<0.05,0.01),while in Cx43+/+mice and in comparison with model group,the spleen index,thymus index and leukocyte number of acupuncture group were significantly higher(P<0.05,0.01) and no significant differences were found between acupuncture group and control group(P>0.05).But in Cx43+/-mice,no obvious differences were found between acupuncture and model groups in the aforementioned 3 indexes(P>0.05),showing a disappearance of the effect of acupuncture in raising immune function after Cx43 knockout.There were no obvious differences between two control groups and between two model groups in the 3 indexes of Cx43+/+mice and Cx43+/-mice.The immune function of Cx43+/+mice was obviously stronger than that of Cx43+/-mice in acupuncture group.Conclusion: Knockout of Cx43 gene inhibits the effect of acupuncture in reinforcing mouse immunity,suggesting an important role of Cx43 in the transmission of acupuncture signals for adjusting immunity function.关键词：Cx43 gene knockout mice;Acupuncture;Immune function1034|0|2更新时间：2023-08-11
- 摘要：Objective: To compare the effects of electroacupuncture(EA) of "Neiguan" and other acupoints on Na+-K+-ATPase activity and its gene expression in ischemic myocrardial cell membrane in rats.Methods: A total of 50 Wistar rats were randomly divided into pseudo-operation(control),model,Neiguan(PC 6),Shenmen(HT 7) and Hegu(LI 4) groups,with 10 rats in each group.Myocardial ischemia-reperfusion(I/R) model was duplicated by occlusion of the descending anterior branch of the left coronary artery and reperfusion.EA(30/100 Hz,2-4 mA) was applied to the above-mentioned acupoints for 20 min respectively.Na+-K+-ATPase activity was determined by inorganic phosphorus colorimetry,and Na+-K+-ATPase gene expression was detected using reverse transcription polymerase chain reaction(RT-PCR) technique.Results: Compared with control group,the activity of Na+-K+-ATPase in model,PC6,HT7 and LI4 groups decreased significantly after myocardial I/R(P<0.05,0.01);while in comparison with model,the activity of Na+-K+-ATPase in PC6 group increased considerably(P<0.01).Regarding the expression of Na+-K+-ATPase mRNA,compared with control group,it was down-regulated significantly in model,HT7 and LI4 groups(P<0.01);while in PC6 group,Na+-K+-ATPase mRNA expression was up-regulated markedly compared with model group(P<0.05);The activity of Na+-K+-ATPase and the expression of Na+-K+-ATPase mRNA in HT7 and LI4 groups were significantly lower than those in PC6 group(P<0.01,0.05).No significant differences were found between HT7 and LI4 groups in the activity of Na+-K+-ATPase and the expression of Na+-K+-ATPase mRNA(P>0.05).Conclusion: EA of "Neiguan"(PC 6) may potentiate the activity of Na+-K+-ATPase and up-regulate Na+-K+-ATPase mRNA expression,which may contribute to its protective effect on ischemic cardiocytes.1137|0|11更新时间：2023-08-11
- 摘要：Objective: To observe the effects of acupoint-embedding(AE) of collagen plus Tetramethylpyrazine and electroacupuncture(EA) on the contents of TNF-α and IL-6 in hippocampus tissue in rats with focal cerebral ischemia-reperfusion(CI-R) injury.Methods: A total of 120 SD rats were randomly divided into normal control(n=8),sham operation(n=24),model(CI-R,n=24),EA(n=24) and AE(n=24) groups,and the later 4 groups were further divided into 24 h,72 h and 120 h subgroups(time-points) separately,with 8 cases in each.CI-R model was established by middle cerebral artery occlusion(MCAO) and reperfusion.For animals of AE group,the medicinal thread consisting of collagen and Tetramethylpyrazine was implanted into "Dazhui"(GV 14) and bilateral "Neiguan"(PC 6),once daily.For rats of EA group,EA(120 cycles/min,1 mA) was applied to GV14 and PC6 for 30 min,once daily.The contents of TNF-α and IL-6 in the hippocampus were detected by using radio-immunoassay after processing the tissue samples(homogenate,centrifuge).Results: The contents of TNF-α and IL-6 in hippocampus tissue of model group at 24 h,72 h and 120 h time-points were significantly higher than those of normal control and sham operation groups(P<0.05),while after EA and AE,the contents of TNF-α at the 3 time-points decreased significantly(P<0.05),and IL-6 contents at the same 3 time-points increased further and significantly(P<0.05).Comparison between EA and AE groups showed that the contents of TNF-α of the later group at 72 h and 120 h were significantly lower than those of EA group(P<0.05),while IL-6 contents of AE group were significantly higher than those of EA group at the same time-points(P<0.05).Conclusion: Both EA and AE of collagen and Tetramethylpyrazine can evidently lower TNF-α content and significantly raise IL-6 level in hippocampus in rats with cerebral ischemia/reperfusion injury and the effect of AE is significantly superior to that of EA,which may contribute to their protective effects on ischemic cerebral neurons.1065|0|4更新时间：2023-08-11
- 摘要：Objective: To observe the regularity of electroacupuncture(EA) analgesia and to analyze its relation to hypothalamus-pituitary-adrenal cortex axis function in chronic constrictive injury(CCI) and ovariectomy(OVX) rats.Methods: A total of 110 Wistar rats anesthetized with mixture solution of 1.5% chloralose(50 mg/kg) and 25% urethrane(420 mg/kg,i.p.) were randomized into control(n=10),CCI(n=10),CCI+EA(n=30),OVX+CCI(n=30),OVX+CCI+EA(n=30) groups,and the later 3 groups were further divided into 2 times(2 t),2 weeks(2 w)and 3 w time courses,with 10 cases in each.Forty-five days after OVX,Morris water maze test was conducted to evaluate the OVX rats' memory-learning ability.Chronic pain model was established by ligating the right sciatic nerve with a piece of suture.EA(2/15 Hz,1 mA) was applied to bilateral "Zusanli"(ST 36)-"Yanglingquan"(GB 34) for 30 min,once daily for 2 t,2 w,3 w respectively.The paw withdrawal latency(PWL) was detected to be used as the pain threshold.Under deep anesthesia,the rat was decapitated for collecting blood samples.Plasma adrenocorticotropic hormone(ACTH),β-endorphine(EP),cortisone(COR) contents were detected using radioimmunoassay.Results: In comparison with control group,PWL difference values(PWLDV) of CCI+EA,OVX+CCI and OVX+CCI+EA groups increased significantly(P<0.05),suggesting a marked decrease of pain threshold.Compared with CCI group,PWLDV of CCI+EA group at 3 w decreased significantly(P<0.05),being close to normal control group(P>0.05).Compared with OVX+CCI group,PWLDV of OVX+CCI+EA at 2 w and 3 w lowered significantly(P<0.05),suggesting an evident pain relief.In comparison with CCI+EA group,PWLDV of OVX+CCI+EA group at most time courses were considerably higher(P<0.05),showing a better cumulative analgesic effect in CCI rats without OVX.In CCI group,plasma β-EP increased slightly,ACTH had no clear changes,and COR lowered lightly at 2 t.No significant differences were found between control and CCI+EA groups in β-EP and ACTH levels at 2 w and 3 w(P>0.05),only COR levels of CCI+EA group at 2 w and 3 w increased significantly(P<0.05).Compared with control group,β-EP levels of OVX+CCI group at 2 w and 3 w increased significantly(P<0.05);plasma ACTH had no marked changes(P>0.05);COR contents of OVX+CCI group decreased evidently at 2 t and increased markedly at 2 w(P<0.05).Compared with OVX+CCI group,in OVX+CCI+EA group,β-EP levels of 2 t and 2 w decreased significantly(P<0.05);ACTH levels increased evidently at 2 t and 3 w,and decreased markedly at 2 w(P<0.05);and COR level at 2 w decreased significantly(P<0.05).It indicated that when cumulative EA analgesia appeared,in CCI animals,only plasma COR level increased pronouncedly,while in OVX+CCI rats,both plasma β-EP and COR contents decreased evidently.Conclusion: Both plasma β-EP and COR are involved in the accumulative analgesic effect of EA in the rat,and decline of learning memory ability may weaken the analgesic effect of EA to a certain degree,but no clear correlation tendency is found between changes of plasma β-EP and COR and the improvement of pain behavior.关键词：Acupuncture analgesia;Cumulative effect;β-EP;ACTH;COR1046|0|9更新时间：2023-08-11
- 摘要：Objective: To compare the effects of acupuncture stimulation of different acupoints on discharges of hypothalamic sexual arousal stimulation-related excitatory neurons in the rat so as to selected effective acupoints for regulating genito-endocrine function.Methods: Experiments were performed in 32 female Sprague-Dawley rats.Examination of vaginal castoff cell smear(HE staining) was performed to determine the rats' estrous cycle.Those being in proestrus/estrus were 14 animals and those being in diestrus/metaestrus were 18.Extracellular discharges of neurons within the medial preoptic area,the arcuate nucleus and the paraventricular nucleus of the hypothalamus(AP: 4.0-9.0 mm,R: <1.0 mm,L: <2.0 mm) were recorded by using glass micro-pipettes in anesthetized rats(10% urethane).Sexual arousal stimulation was made by using a cotton-ball-stick to touch the clitoris repeatedly(30 s).When a marked change of the neuronal firing rate was found,β-estradiol(20 ng/mL,1.5-2.5 mL/kg) was injected intravenously from the external jugular vein for observing its feedback regulatory effect.Acupoints "Neiguan"(PC 6),"Shanzhong"(CV 17),"Jueyinshu"(BL 14),"Zhongwan"(CV 12),"Shenshu"(BL 23),"Guanyuan"(CV 4),"Zigong"(EX-CA 1) and "Zusanli"(ST 36) were punctured and stimulated manually by twirling the acupuncture needle continuously for 30 s.Results: After manual acupuncture,the sequence of acupoints with a stronger excitatory reaction of the firingrates of the hypothalamic neurons related to sexual arousal stimulation was EX-CA1,CV4,ST36,BL23,CV12,BL14,PC6 and CV17 in proestrus/estrus;and CV4,EX-CA1,ST36,CV12,BL23,BL14,PC6 and CV17 respectively in diestrus/metaestrus.According to the place of the stimulated acupoints potentiating the electrical activity of the hypothalamic sexual arousal stimulation-related neurons,the sequence from stronger to the weaker responses was lower abdomen(below umbilicus),lower limb,lower back(L1-S5),upper abdomen,upper back(above T12),thorax,and upper limbs.After administration of estradiol,the excitatory response of these sexual arousal-related neurons decreased significantly in both estrus and non-estrus(P<0.05).Conclusion: Acupuncture can effectively activate the electrical activity of hypothalamic sexual arousal stimulation-related excitatory neurons.The closer the acupoint to the genital organs,the stronger is the excitatory effect,including "Zigong"(EX-CA 1),"Guanyuan"(CV 4) and "Zusanli"(ST 36) among the 8 acupoints observed.关键词：Acupuncture;Hypothalamus;Sexual arousal-related neurons;Oestrous cycle;Specificity of acupoints1153|0|2更新时间：2023-08-11
- 摘要：Objective: To observe the effect of "Weizhong"(BL 40) bleeding on sciatic nerve conduction velocity(SNCV) and interleukin-1α(IL-1α) content of the lumbar vertebral nucleus pulposus tissue in experimental lumbar intervertebral disc protrusion(LIDP) rabbits so as to explore the underlying mechanism of blood letting in the treatment of LIDP.Methods: Forty healthy New Zealand rabbits were randomly assigned to control,model,BL40 and non-point(1 cm medial to BL 40) groups,with 10 cases in each group.LIDP model was established by pushing the intervertebral disc tissue rightward to protrude the posterior longitudinal ligament with a self-made instrument after exposing the L6-7 vertebrae and intervertebral space.Blood-letting was performed at "Weizhong"(BL 40) and non-point by using a triangle-edged needle to prick the local tissue,once daily and continuously for 7 days.SNCV was detected by using BL-410 physiological signal recording system,and the content of IL-1α in L6-7 intervertebral disc tissue determined with enzyme linked immunsorbent assay(ELISA).Results: In comparison with control group and pre-modeling,SNCV decreased significantly in model,BL40 and non-acupoint groups after LIDP;while compared with model group,values of SNCV in BL40 group increased considerably(P<0.05),no significant changes were found between non-acupoint group and model group(P>0.05).Compared with control group,the contents of IL-1α in the nucleus pulposus in model and non-acupoint groups increased remarkably(P<0.05,0.01),but no significant difference was found between control and BL40 groups in IL-1α level(P>0.05).Conclusion: Blood-letting at "Weizhong"(BL 40) can relieve LIDP-induced nerve injury and mechanical oppression to improve SNCV,which may be closely related to its effect in decreasing inflammatory factor IL-1α level.关键词：Pricking blood therapy;LIDP;SNCV;IL-1α1188|0|7更新时间：2023-08-11
- 摘要：Objective:To observe the effect of small needle-knife lysis on plasma calcitonin gene-related peptide(CGRP),endothelin(ET),6-keto-prostaglandin F1α(6-keto-PGF1α),thromboxane A2(TXA2) contents in rats with experimental third lumbar vertebra transverse process syndrome(TLVTPS)so as to explore its underlying mechanism in clinical treatment.Methods: Forty SD rats were randomly divided into normal control,model,lysis and EA groups.TLVTPS model was established by embedding a piece of gelatin sponge(0.5 cm×0.5 cm) to the transverse process of the 3rd lumbar vertebra under anesthesia.EA(2/100 Hz,1-2 mA) was applied to left "Shenshu"(BL 23)-"Yaoyangguan"(GV 3) for 20 min,once every other day,6 times altogether.For animals of lysis group,the lysis was performed by using a small needle-knife in the induration spot or cord-like region near the incision,once a week and twice altogether.Four weeks later after modeling,plasma CGRP,ET,6-keto-PGF1α and TXA2 contents were detected by using radioimmunoassay and enzyme linked immunosorbent assay(ELISA).Results: Compared with normal control group,plasma CGRP,ET,TXA2 and 6-keto-PGF1α increased significantly in model group(P<0.01);in comparison with model group,plasma CGRP,TXA2 and 6-keto-PGF1α in both EA and lysis groups decreased considerably(P<0.05,0.01).No significant differences were found between EA and lysis groups in plasma CGRP,ET and 6-keto-PGF1α levels(P>0.05).Conclusion: Both EA and lysis of acupotomology have an adjusting effect on vasoactive substances(CGRP,TXA2 and 6-keto-PGF1α) levels in TLVTPS rats,which may contribute to their effects in improving local blood circulation and relieving soft tissue injury in the treatment of third lumbar vertebra transverse process syndrome.关键词：Lysis of acupotomology;Third lumbar vertebra transverse process syndrome;Vasoactive substances1019|0|5更新时间：2023-08-11
- 摘要：Objective: To compare the effects of electroacupuncture(EA) and moxibustion on the degranulated mast cell number and distribution in "Dazhui"(GV 14) region of rats.Methods: Fifteen Wistar rats were randomly divided into normal control,EA and moxibustion groups,with 5 cases in each group."Dazhui"(GV 14) was stimulated by EA(3/10 Hz,2-4 V,20 min) or moxibustion(2 cones,20 min),thereafter,the tissues of GV14 region were sampled,quickly frozen,sectioned(20 μm) and stained with toluidine blue separately for observing the degranulated state of mast cells under microscope.Results: The mast cells(MCs) distributed widely in GV14 region from the dermis,subcutaneous tissue to muscle layer.Compared with control group,MCs of moxibustion group were significantly fewer in the number(P<0.05),and those degranulated MCs in both EA and moxibustion groups were evidently more in the number(P<0.01),and the number and percentage of the degranulated MCs in moxibustion group were significantly more than those of EA group(P<0.05),suggesting that EA and moxibustion could promote the release of granules of mast cells in the stimulated acupoint region,and the effect of moxibustion is stronger.Conclusion: Both EA and moxibustion can promote the degranulation of MCs,and the effect of moxibustion is markedly stronger in potentiating the release of granules from MCs in GV14 in rats.关键词：Moxibustion;Electroacupuncture;Mast cells;Degranulation1100|0|9更新时间：2023-08-11
- 摘要：Objective: To study the interrelation between the change of temperature and Ca2+-,Mg2+-ATPase activity in the tissues along the running course of meridians in the rabbit.Methods: Seven healthy mongrel rabbits were used in this study.Before and after moxibustion of "Zusanli"(ST 36) and "Yinlingquan"(SP 9),the cutaneous temperature along the Stomach Meridian and Spleen Meridian was detected with an infra-red thermography.The tissues showing higher temperature(including skin,subcutaneous tissue and muscle,100 mg) and non-higher temperature(skin,subcutaneous tissue and muscle about 0.5 cm beside the higher temperature region,100 mg) after moxibustion were sampled respectively for detecting the activity of Ca2+-and Mg2+-ATPase with enzymologic method.Results: After moxibustion of "Zusanli"(ST 36) and "Yinlingquan"(SP 9),the temperature of the skin along the Stomach Meridian and Spleen Meridian on the same side increased significantly(P<0.05,0.01);correspondingly,the activity of Mg2+-ATPase in the higher temperature regions(lateral side of the left thigh,and the medial side of the right hindlimb) increased moderately and significantly separately in comparison with the control regions(P<0.05).No marked changes were found in the activity of Ca2+-ATPase in the same tissues of the higher temperature regions(P>0.05).Conclusion: In the tissues of higher temperature region after moxibustion of SP9,Mg2+-ATPase activity increased evidently,that may contribute to the increase of temperature along the skin of the Spleen Meridian after moxibustion,while Ca2+-ATPase may play a minor role therein.关键词：Moxibustion;Cutaneous temperature along meridian;Ca2+-ATPase activity;Mg2+-ATPase activity971|0|4更新时间：2023-08-11
- 摘要：Objective: To explore the underlying mechanisms of acupuncture in treating diabetic nephropathy(DN) by observing the effect of acupuncture on blood rheology of DN.Methods: A total of 54 cases of DN patients were randomly divided into control (n=24) and acupuncture group(n=30).Patients of control group were treated with diet-control,oral administration of Gliguidone(30-60 mg,t.i.d.) or subcutaneous injection of insulin,and those of acupuncture group treated with the same medication as those of control group and additional manual acupuncture stimulation of Ganshu(BL 18),Pishu(BL 20),Zusanli(ST 36),etc.,once daily for 30 days.Hemorheology was detected with LBY-N 6 A Automatic Hemorheological Analyser.The treatment duration in 2 groups was 30 days.Results: After the treatment,of the 24 and 30 cases in control and acupuncture groups,6(25.0%) and 16(53.3%) cases experienced remarkable improvement in their symptoms;10(41.6%) and 12(40.0%) had improvement,8(33.3%) and 2(6.7%) failed,with the effective rates being 66.7% and 93.3% respectively.Self-comparison showed that after the treatment,no significant changes were found in lower shear rate(LSR) and higher shear rate(HSR) of whole blood viscosity,plasma viscosity(ηp),hematocrit(HCT) and profibrin in control group;while LSR of whole blood viscosity,ηp and profibrin in acupuncture group decreased significantly(P<0.05).The therapeutic effect of acupuncture group was significantly superior to that of control group in lowering LSR of whole blood viscosity and profibrin(P<0.05).Conclusion: Acupuncture can improve DN patients' clinical symptoms and blood rheology,and hence,has a certain effect in postponing the development of DN.关键词：Diabetic nephropathy;Acupuncture therapy;Hemorheology993|0|5更新时间：2023-08-11
- 摘要：Objective: To observe the effect of different needle-retaining duration on hemorheology in ischemic stroke patients in order to explore its underlying mechanism in the treatment of ischemic stroke.Methods: A total of 251 ischemic apoplexy patients were,according to their state(mild,moderate and severe) of disease,randomly divided into 20 min,40 min and 60 min groups respectively.Acupoints Jianyu(LI 15),Quchi(LI 11),Waiguan(TE 5),Hegu(LI 4),Futu(ST 32),Zusanli(ST 36),etc.were punctured and stimulated electrically with parameters of 2 Hz,2-6 mA for 20 min,40 min and 60 min separately,once daily for 10 times.In addition,the patients were also treated with medicines for lowering intracranial pressure as manicol,etc.Higher shearing rate(HSR) and lower shearing rate(LSR) of whole blood viscosity(ηb),plasma viscosity(ηp),hematocrit(HCT) and profibrin were detected separately before and after the treatment.Results: After acupuncture treatment,of the 83,80 and 82 cases in 20 min,40 min and 60 min groups,3(3.61%),4(5.00%) and 9(10.98%) were cured basically,15(18.07%),17(21.25%) and 21(25.61%) experienced remarkable improvement in their symptoms and signs,24(28.92%),33(41.25%) and 40(48.78%) had an improvement,41(49.40%),26(32.50%) and 12(14.63%) failed in the treatment,with the markedly effective rates being 21.68%,26.25% and 36.59% and the effective rates being 50.60%,67.50% and 85.37% separately.The effective rate of 60 min group was significantly higher than those of 20 min and 40 min groups(P<0.01,0.05). Self-comparison showed that HSR,LSR of ηb,ηp,HCT and profibrin levels decreased considerably in comparison with pre-treatment in each group(P<0.01).Difference values of HSR,LSR,ηp,HCT and profibrin(pre-treatment-those of post-treatment) in 60 min group were significantly higher than those of 20 min and 40 min groups(P<0.05,0.01),and those of HSR,HCT and profibrin of 40 min group were markedly higher than those of 20 min group(P<0.01,0.05).The therapeutic effect of 60 min group was the best.Conclusion: Acupuncture can effectively improve stroke patients' symptoms and signs,and lower various parameters of hemorheology.关键词：Ischemic stroke;Acupuncture therapy;Needle retaining time;Hemorheology940|0|8更新时间：2023-08-11
- 摘要：Objective: To evaluate the analgesic and therapeutic effects of electro-superficial-acupuncture(ESA) of Sanyinjiao(SP 6) for treating primary dysmenorrhea(PD).Methods: A total of 171 patients were randomly divided into ESA(n=57),superficial acupuncture(SA)(n=57) and medication(n=57) groups.For patients in SA group,bilateral SP6 were punctured superficially with special single-use needles,and for those in ESA group,after puncturing,electric stimulation(60 Hz,2-3 V) was applied to SP6 for 30 min.Patients of medication group were ordered to take Brufen sustained-release capsules(0.3 mg,b.i.d.,for 3 days),then,take it again from the 3rd day on before the onset of menstruation to the 2nd day after the onset.The cumulative score of clinical symptoms were evaluated before and after the treatment.Results: Comparison among 3 groups showed that the difference values of score(pre-treatment-post-treatment) of both ESA and SA groups were significantly bigger than that of medication group(P<0.001).After the treatment from 1 min to 30 min,patients with complete relief of dysmenorrhea of ESA group were significantly more than those of SA group during the 1st menstrual cycle(P<0.05).Results of intention-to-treat(ITT) analysis showed that of the three 57 cases in ESA,SA and medication groups,the cured cases were 40,38 and 10,the markedly effective were 9,10 and 27,the effective were 5,4 and 7,and the failed were 3,5 and 13,with the total effective rates being 94.74%,91.23% and 77.19% respectively.The effective rates of ESA and SA groups were significantly higher than that of medication group(P<0.01),and the results of per-protocol analysis(PP) were similar to those of ITT analysis.Conclusion: The analgesic effect of both ESA and SA at SP6 for PD patients is significantly better than that of oral administration of Brufen.关键词：Dysmenorrhea;Acupuncture therapy;Electroacupuncture;Superficial acupuncture;Sanyinjiao(SP 6)903|0|1更新时间：2023-08-11
- 摘要：In the present article,the authors,in the light of their research in recent a decade of years,make an overall summary on the regularities of clinical acupuncture from the stimulated points,the superficial and deep layers,the literature basis and the innovation points.These basic regularities include symmetry or corresponding,segmental innervation,center or central axis,superiority of distal limbs,ending-stimulation accelerating analgesia,periphery-stimulation accelerating easiness and smooth,local feed back,specific feed back,selection of the stimulated points,acupuncture of different layers,etc..They also discuss the possibility of integration of traditional Chinese and Western medicine from the view-points of neuroanatomy,neurophysiology and rehabilitation medicine.Systematic analysis on the regularities of clinical acupuncture makes the ancient meridian-collateral theory and abundant clinical experience summed up in definite concepts,simplifies the complicated theory system of acupuncture learning,and favors the communication about the terminology of Chinese medicine and Western medicine.关键词：Clinical regularities of acupuncture;Integration of Chinese and Western medicine;Theoretical research735|0|0更新时间：2023-08-11
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- 摘要：In this article,the authors make an analysis on the regularity of correlation between pathological reactions of acupoints and Zangfu organs/meridians,current clinical application and mechanism research,and summarize the relative specificity of the correlation between abnormal reactions of acupoints and states of Zangfu organs/meridians.In addition,the authors also point out some shortcomings in current researches on the above-mentioned aspects,for examples,only observation on the phenomenon without definite conclusion on the regularity of acupoint reactions,being restricted in the objective specificity,etc..They stress that we should sum up a series of regularities for clinical application(early diagnosis),and conduct profound research on its underlying mechanism in the coming days.1083|0|4更新时间：2023-08-11
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