最新刊期
卷 35 ， 期 4 ， 2010
- 摘要：Objective To investigate the effect of moxibustion on the expression of IL-1β,IL-2 and IL-6 proteins and mRNA in the cerebral cortex in tumor-bearing mice so as to study its mechanism underlying immunomodulation. Methods Forty Balb/c mice were randomly divided into control,tumor-bearing,non-acupoint moxibustion (N-AM)and acupoint-moxibustion (AM) groups (n=10/group). Moxibustion was applied to "Dazhui" (GV 14),once every other day for 6 times. The expression of IL-1β mRNA,IL-2 mRNA and IL-6 mRNA was detected by in situ hybridization,and the immunoactivity of IL-1β,IL-6 and IL-2 determined by immunohistochemistry. Results Compared to the control group,the expression levels of IL-1β mRNA and IL-2 mRNA,IL-1β and IL-2 in the cerebral cortex of the tumor-bearing group were down-regulated significantly ( P<0.05 ,P<0.01 ),while those of IL-6 mRNA and IL-6 up-regulated significantly ( P<0.05 ). Compared to the tumor-bearing group,the expression of IL-1β mRNA and IL-2 mRNA,IL-1β and IL-2 in the cerebral cortex in AM group were increased considerably ( P<0.05 ,P<0.01 ); while cortical IL-6 immunoactivity in N-AM group was decreased significantly ( P<0.05 ),and IL-6 mRNA had no significant change in N-AM group ( P>0.05 ). Comparison between AM and N-AM groups showed that the expression levels of cortical IL-1β mRNA and IL-2 mRNA,and IL-1β and IL-2 proteins of the former group were obviously higher than those of the later group ( P<0.05 ,P<0.01 ); while the immunoactivity of cortical IL-6 of AM group was significantly lower than that of N-AM group ( P<0.05 ). No significant difference between AM and N-AM groups in the expression of IL-6 mRNA ( P>0.05 ). Conclusion Moxibustion treatment can up-regulate the expression of cortical IL-1β mRNA,IL-2 mRNA,IL-1β and IL-2 proteins,and down-regulate the expression of IL-6 mRNA and IL-6 in tumor-bearing mice,which may contribute to its effect in improving the immunosuppressing state under tumor conditions.973|1120|5更新时间：2023-08-11
- 摘要：Objective To observe the influence of moxibustion on the cyclin and cellular proliferin of the cerebral cortex in senile mice so as to explore its underlying mechanism in delaying aging. Methods Sixty male mice were randomly and equally divided into control,model,moxibustion of "Zusanli" (ST 36) and "Xuanzhong" (GB 39,M-ST 36-GB 39),moxibustion of "Baihui" (GV 20) and "Guanyuan" (CV 4,M-GV 20-CV 4),and medication groups. The aging model was established by subcutaneous injection of D-galactose for 42 days. Moxibustion was applied to ST 36,GB 39,GV 20 and CV 4 separately for 3 moxa-cones,once every other day for one month. The expression of cell cycle protein P 16 and retinoblastoma (pRb),and c-fos protein in the cerebral cortex tissue of the senile mice were detected by immunohistochemistry. Results Compared with control group,the number of P 16 immunoreaction (IR) positive neurons in the cerebral cortex increased significantly in the model group ( P<0.01 ),and those of cortical pRb and c-fos IR-positive neurons decreased considerably in model group ( P<0.01 ). In comparison with the model group,the number of cortical P 16 IR-positive neurons reduced significantly in M-ST 36-GB 39,M-GV 20-CV 4 and medication groups ( P<0.01 ),and those of cortical pRb and c-fos IR-positive neurons increased remarkably in M-ST 36-GB 39,M-GV 20-CV 4 and medication groups ( P<0.01 ,P<0.05 ). No significant differences were found in the aforementioned 3 indexes among M-ST 36-GB 39,M-GV 20-CV 4 and medication groups ( P>0.05 ). Conclusion Moxibustion of ST 36-GB 39 and GV 20-CV 4 can down-regulate the P 16 expression,and up-regulate pRb and c-fos protein expression in the cerebral cortex of senile mice,which possibly contributes to its effect in delaying aging.关键词：Moxibustion;Aging;Cerebral cortex;Cell cycle protein P 16;Retinoblastoma (Rb);c-fos expression1360|337|6更新时间：2023-08-11
- 摘要：To observe the effect of Spleen-Meridian-acupoint injection of Lentinan on the immunologic function in spleen-deficiency rabbits. Methods A total of 54 Newzealand rabbits were randomly divided into normal (n=10),model (n=8),intramuscular injection (n=10),Sanyinjiao (SP 6,n=10),Diji (SP 8,n=8) and Xuehai (SP 12,n=8) groups. Spleen-qi deficiency model was established by intragastric administration of 100% crude Radix et Rhizoma Rhei decoction (15 mL/kg/day× 10 d ),and then Lentinan (LNT,0.025 mg/kg/2 day×5) was injected into the aforementioned acupoints of the Spleen Meridian. The erythrocyte immunologic function(RBC-C 3 bR,RBC-IC),hemolysin(IgM)and changes of physical signs of the rabbits were observed. Results In comparison with the control group,the rabbits' body weight,rectal temperature,RBC-C 3 bR% and serum IgM level were decreased significantly in model group ( P<0.05 ); while in comparison with the model group,the body weight in SP 8 group,retal temperature in SP 9 and SP 8 groups,RBC-C 3 bR% in SP 9 and SP 12 groups,and serum IgM levels in SP 9,SP 8 and SP 12 groups increased considerably ( P<0.05 ,P<0.01 ). Comparison among the 4 treatment groups showed that the effect of SP 12 was superior to that of intramuscular injection group in upregulaing RBC-C 3 bR%,and the effects of SP 9,SP 8 and SP 12 groups were significantly superior to those of intramuscular injection group in upregulating serum IgM level ( P<0.05 ). Conclusion The Spleen-Meridian-acupoint injection of LNT is superior to that of intramuscular injection of LNT in improving the spleen-qi deficiency rabbits' symptoms and immunologic function.关键词：Spleen Meridian;Spleen-qi deficiency;Acupoint injection;Lentinan;Immunologic function1292|270|1更新时间：2023-08-11
- 摘要：Objective To observe the effect of electroacupuncture (EA) on the expression of glucocorticoid (GC) mRNA and GC in the hippocampus,hypothalamus and pituitary in depression rats so as to study its mechanism underlying EA-resisting depression. Methods Seventy SD rats were randomized into normal control,model,Fluoxetine (Flu),constraint-stress,EA,RU 486 (an antagonist of GC) and EA+RU 486 groups (n=10/group).Chronic depression model was established by lonely raising and chronic unpredictable mild stress for 21 days.EA (2 Hz,0.6 mA) was applied to "Baihui" (GV 20) and "Yintang" (EX-HN 3) for 20 min ,once daily for 21 days.Subcutaneous injection of RU 486 (20 mg/kg) was given to the rats from the 14 th day on and continuously for 7 days in order to block the negative feedback reflex of hypothalamus-pituitary-adrenal (HPA) axis.Cortisol (CORT) content of the adrenal gland tissue was detected by radioimmunassay.The expression of GC receptor (GR)mRNA in the hippocampus,hypothalamus and pituitary tissues was determined by real-time quantitative reverse transcription-polymerase chain reaction (RT-PCR). Results Compared with the normal control group,adrenal CORT content of model group was increased significantly ( P<0.05 ),and in comparison with model group,adrenal CORT level of EA group decreased evidently ( P<0.05 ).Comparison between the RU 486 and EA+RU 486 groups showed that the adrenal CORT content,and hippocampal GR mRNA expression level of the latter were remarkably lower than those of the former ( P<0.05 ). Compared with the normal control group,the expression level of GR mRNA of the hipppocampal and pituitary tissues in the model,constraint-stress,and RU 486 groups,and those of the hypothalamus in the constraint-stress and RU 486 groups were down-regulated significantly ( P<0.05 ).In comparison with the constraint-stress group,hippocampal,hypothalamic and pituitary GR mRNA expression level in the EA group were upregulated considerably ( P<0.05 ).No significant differences were found among model,Flu,constraint-stress,RU 486 and EA+RU 486 groups in the ardenal CORT contents,and hippocampal,hypothalamic and pituitary GR mRNA expression levels ( P>0.05 ). Conclusion EA can effectively down-regulate adrenal CORT content and hippocampal GR mRNA expression and normalize the function of HPA axis negative feed reflex in the depression rats,which may contribute to its effect in relieving depression.关键词：Electroacupuncture;Depression;Chronic stress;Glucocorticoid receptor expression;Adrenal corticosterone;Hippocampus;Hypothalamus-pituitary-adrenal axis1272|743|5更新时间：2023-08-11
- 摘要：Objective To observe the effect of needle-implantation (NI) at "Neiguan" (PC 6) on the expression of myocardial transforming growth factor-beta 3 Protein(TGF-β 3) and mRNA in Chinese miniswine with myocardial ischemia (MI) injury. Methods A total of 32 Chinese Guizhou miniswine were randomly and equally divided into Sham-operation group,model group,NI-PC 6 group and NI-Geshu (BL17,NI-BL17) group. MI injury model was established by occlusion of the descending anterior branch of the left coronary artery. Two acupuncture needles (veterinary use) were separately and subcutaneously implanted into "Neiguan" (PC 6) and "Geshu" (BL17) areas for 7 days. TGF-β 3 protein and mRNA expressions were determined by Western blot and real-time PCR techniques,separately. Results In comparison with the sham-operation (sham) group,TGF-β 3 protein and mRNA expressions in model group were upregulated significantly( P<0.05 ). While compared with the model group,myocardial TGF-β 3 mRNA expression was upregulated considerably in NI-PC 6 group ( P<0.01 ),rather than in NI-BL17 group ( P>0.05 ),and myocardial TGF-β 3 expression in both NI-PC 6 and NI-BL17 groups was upregulated obviously ( P<0.01 ). Comparison between NI-PC 6 and NI-BL17 groups showed that the expression levels of myocardial TGF-β 3 protein and mRNA were significantly higher in NI-PC 6 group than in NI-BL17 group ( P<0.05 ). Conclusion Needle-implantation of "Neiguan" (PC 6) can upregulate myocardial TGF-β 3 protein and mRNA expression in MI Chinese miniswine,which may contribute to its effect in improving the ischemic myocardial injury by way of enhancing the angiopoiesis.关键词：Needle-implantation;Neiguan (PC 6);Myocardium ischemia;Myocardial TGF-β 3;TGF-β 3 mRNA1013|351|8更新时间：2023-08-11
- 摘要：Objective To observe the content of leptin in the abdominal subcutaneous tissues of the higher temperature zone along the Gallbladder (GB) Meridian in cholecystitis rabbits so as to explore the correlation between the temperature response and the leptin level. Methods Twenty-five rabbits were randomized into normal control group (n=10) and cholecystitis model group(n=15). Cholecystitis model was established by injection of Escherichia coli solution (0.1 mL) into the gallbladder via common bile duct after surgery. Three,7 and 11 days following modeling,the abdominal surface thermographic images along the GB Meridian were collected by the AGA-782-type infrared imaging system (AGA's capacity). And then the subcutaneous tissues of the high temperature reaction region and the contralateral corresponding tissues of different groups were collected for assaying the leptin contents in the supernatant by radioimmunoassay after processing (homogenization and centrifugation) and for observing the morphological structure under light microscopy after sectioning and staining (toluidine blue). Results Thermographic images showed that about 70% of the animals in the model group,various lengths of high temperature reaction (0.5-1.4 ℃) zones or bands in the abdominal region along the bilateral GB Meridian were seen,in comparison with the control group. The leptin levels in the ipsilateral (affected side) and contralateral (healthy side) tissues of the abdominal high temperature reaction zones along the GB Meridian were significantly higher in the model group than in the control group ( P<0.01 ),suggesting a close correlation between the leptin content change and the high temperature reaction. In addition,most fat cells were crowded to distribute closely along the blood vessels in the subcutaneous tissues of the higher temperature reaction zone in the model group,but those of the control group distribute more loosely along the blood vessels. Conclusion The leptin content in the abdominal subcutaneous tissues of high temperature reaction zone along the GB Meridian is higher in cholecystitis rabbits,suggests a relevance of the endocrine function of fat cells to the high temperature reaction along the GB Meridian.关键词：Cholecystitis;High temperature reaction along the meridian;Subcutaneous leptin1014|158|2更新时间：2023-08-11
- 摘要：Objective To observe the effects of electroacupuncture (EA ) on leptin and leptin receptor(Ob-rb) mRNA expression in the hypothalamus of nonalcoholic fatty liver disease (NAFLD) rats,so as to reveal its underlying mechanism in the treatment of NAFLD inflammation. Methods Thirty-two male SD rats were randomly divided into control group (n=10),model group (n=11) and EA group (n=11). NAFLD model was established by feeding the animals with high fat diet for 8 weeks. EA (10 Hz,1.5 V,30 min) was applied to unilateral "Fenglong" (ST 40) and "Zusanli" (ST 36),once daily for 4 weeks. After the treatment,all the rats were sacrificed for collecting the liver to make pathological observation after HE staining and for taking the hypothalamus tissue out to detect the leptin mRNA and leptin receptor (Ob-rb) mRNA expression by reverse transcription polymerase chain reaction (RT-PCR). Serum total cholesterol (TC) and triglyeride (TG) contents were detected by chromatometry. Results Compared with the control group,serum TC and TG levels increased significantly in the model group ( P<0.05 ). While compared with mo-del group,both TC and TG levels in EA group were reduced considerably ( P<0.05 ). In comparison with control group,the expression of hypothalamic leptin mRNA and Ob-rb mRNA was down-regulated remarkably ( P<0.05 ),while 4 weeks after EA treatment,both leptin mRNA expression and Ob-rb mRNA expression were up-regulated obviously ( P<0.05 ). Conclusion EA can lower serum TG and TC contents in NAFLD rats,which is closely related to its effects in up-regulating the expression of hypothalamic leptin mRNA and Ob-rb mRNA.关键词：Electroacupuncture;NAFLD;Hypothalamus;Leptin;Ob-rb1132|241|5更新时间：2023-08-11
- 摘要：Objective To observe the role of large-diameter fibers of infraorbital nerve (ION) in "Sibai" (ST 2)-electroacupuncture(EA)induced analgesia in visceral pain (VP) rats. Methods A total of 36 SD rats were randomized into control,VP,EA,ION transaction,snake venom(SV) and saline groups,with 6 rats in each group.EA(2 Hz/20 Hz) was applied to bilateral "Sibai" (ST 2) for 20 min.VP model was established by intraperitoneal injection of 0.6% acetic acid(10 mL/kg).Bilateral ION were transacted or pretreated by regional application of snake venom to selectively destroy A fibers,respectively.Behavior reactions were assessed by counting abdominal muscular contractions. Meanwhile,c-fos expression in the nucleus of the solitary tract (NTS) and paratrigeminal nucleus (PTN) was displayed by immunohistochemistry. Results In comparison with control group,the numbers of abdominal muscular contraction,and c-fos immuno-reaction(IR)positive neurons in both NTS and PTN increased significantly in VP group( P<0.001 );while in comparison with VP group,the numbers of the abdominal contraction,and c-fos IR-positive neurons of both NTS and PTN in EA and SV and saline groups decreased considerably( P<0.05 ,P<0.01 ).No significant differences were found between ION transaction and VP groups in the abdominal contraction number,and c-fos IR-positive neurons in both NTS and PTN areas,and among EA and SV and saline groups in the numbers of abdominal contraction and c-fos IR-positive neurons of both NTS and PTN ( P>0.05 ). Conclusion The large-diameter (A) fibers of ION are not the major afferent fibers affecting EA-ST 2 induced analgesia in visceral pain rats;and somatic sensory afferents from orofacial areas and visceral pain input converge in the NTS and PTN,which may be the basis of the EA analgesia in the present study.关键词：Visceral pain;Electroacupuncture;Snake venom;EA analgesia;Afferent pathway;Large-diameter fibers983|184|1更新时间：2023-08-11
- 摘要：Objective To compare the effects of electroacupuncture (EA) of Shu-acupoint "Weishu" (BL 21),Mu-acupoint "Zhongwan" (CV 12) and BL 21+CV 12 on serum large molecular metabolites in functional dyspepsia (FD) rats. Methods A t otal of 50 Wistar rats were randomly divided into control,model,BL 21,CV 12 and BL 21+CV 12 groups (n=10/group). FD model was established by clamping the rats' tails for 30 min,once every 3 h,4 times daily for 7 days. EA was applied to BL 21,CV 12,or BL 21+CV 12,respectively for 20 min,once daily for 10 days. The rats' venous blood was collected for detecting large molecular metabolites by 1H nuclear magnetic resonance (NMR) spectrometer (Varian UnityInova,600 MHz). Segmental integral calculus (0.04 ppm per segment) was performed from 6.0-0 ppm (longitudinal eddy-delay,LED) as defaulted 1H spectra values by using the VNMR software. Data was saved as text or excel files after normalization and then used for pattern recognition analyses. All the data were analyzed by principal component analysis (PCA) using the SIMCA-P 10.04 software (Umetrics AB,Umea,Sweden),and orthogonal signal correction and partial least squares discriminant analysis (OSC-PLS-DA). Results The rat serum proton-LED-1H NMR spectra revealed different metabolic spectra among control,model,BL 21,CV 12,and BL 21+CV 12 groups.PCA and OSC-PLS-DA showed that compared with the normal control group,FD rats in model group displayed serum N-acetylglucoprotein (NAc) content was reduced considerably,high density lipoprotein (HDL) level decreased to a certain degree,while very low density lipoprotein (VLDL) / LDL increased significantly.In comparison with model group,VLDL/LDL was decreased in BL 21,CV 12 and BL 21+CV 12 groups,while NAc content increased. Compared with BL 21 and CV 12 groups respectively,HDL level in BL 21+CV 12 increased to a certain degree. Conclusion EA of BL 21,CV 12 and BL 21+CV 12 groups can reverse or relieve FD induced increase of VLDL/LDL and decrease of serum NAc level in rats,which may contribute to its function in improving symptoms of FD patients.1541|1109|14更新时间：2023-08-11
- 摘要：Objective To observe the curative effect of Chinese drugs-paste separated moxibustion combined with electroacupuncture (EA) for knee osteoarthritis (KOA). Methods A total of 124 cases of KOA patients were randomly and equally divided into moxibustion plus electroacupunture (M+EA) group and medication group by using a random table. Chinese drugs-paste separated moxibustion was applied to Shenque (CV 8) for 9 moxa-cones,combined with EA (4 Hz/20 Hz,1-2 mA) of Liangqiu (ST 34),Heding (EX-LE 2),Neixiyan (EX-LE 4),etc. for 30 min,once daily,5 sessions a week. Patients of medication group were treated by oral administration of Antine Capsule (diclofenac sodium,50 mg,twice daily). After 4 weeks of treatment,the therapeutic effect was evaluated. Results Compared with pre-treatment,the knee-joint pain scores and the indexex of severity of osteoarthritis of both M+EA and medication groups decreased significantly after termination of the treatment and 10 weeks after the treatment ( P<0.01 ),and those of M+EA group were markedly lower than those of medication group ( P<0.05 ). After the treatment,of the two 62 cases in medication and M+EA groups,3 (4.8%) and 8 (12.9%) were under control in their symptoms,16 (25.8%) and 21 (33.9%) had remarkable improvement,31 (50.0%) and 27 (43.5%) were effective,12 (19.4%) and 6 (9.7%) failed in the treatment,with the effective rates being 80.6% and 90.3% respectively. Ten weeks after the treatment,of the two 62 cases in medication and M+EA groups,1 (1.6%) and 7 (11.3%) were under control,10 (16.1%) and 19 (30.6%) had marked improvement,31 (50.0%) and 28 (45.2%) were effective,20 (32.3%) and 8 (12.9%) failed in the treatment,with the effective rates being 67.7% and 87.1%,respectively.The curative effect of M+EA group was significantly superior to that of medication group (P<0.05,P<0.01). Conclusion Chinese drugs-paste-separated moxibustion combined with EA is effective in the treatment of KOA of cold-damp type.关键词：Knee osteoarthritis;Drugs-paste separated moxibustion;Electroacupuncture1187|515|2更新时间：2023-08-11
- 摘要：Objective To observe the effect of abdominal acupuncture on the endocrine and metabolic level in obesity-type polycystic ovarian syndrome (PCOS) patients. Methods Eighty-six PCOS patients were randomly and equally divided into medication group and abdominal acupuncture group.Patients of medication group were treated with metformin (250 mg/time,t. i. d. in the 1 st week,and 500 mg/time,t. i. d. thereafter) for 6 months,and those of abdominal acupuncture group were treated by abdominal acupuncture [Zhongwan (CV 12),Liangmen (ST 21),etc.,once daily for 6 months]. Changes of the body height,body Mass index (BMI),waist-hip ratio (WHR),Ferriman-Galleey score (FGS),menstrual frequency (MF) and ovarian volume (OV) were determined. Serum luteotrophic hormone (LH),free testosterone (T),follicle-stimulating hormone (FSH) contents were detected with radioimmunoassay.Fasting blood glucose (FBG),fasting insulin (FIN),total cholesterol (TC),triglyceride (TG),low density lipoprotein cholesterol (LDL-C),high density lipoprotein cholesterol (HDL-C),Homa insulin resistance index (IRI) were detected with chromatometry respectively. Results After the treatment,BMI,WHR,FGS and OV were reduced significantly in both medication and abdominal acupuncture groups ( P<0.05 ),while MF of the two groups increased evidently ( P<0.05 ),and the effects of abdominal acupuncture group were significantly superior to those of medication group in down-regulating BMI,WHR and upregulating MF ( P<0.05 ). Regarding the reproductive hormons,serum LH,LH/FSH and T levels in the two groups decreased significantly ( P<0.05 ),and the effect of abdominal acupuncture was superior to that of medication group in reducing serum T level ( P<0.05 ). Following the treatment,FBG,BG and FIN and INS contents 2 h after meal,and Homa IR in both medication and abdominal acupuncture groups all decreased considerably ( P<0.05 ),but without significant differences between them ( P>0.05 ). Regarding the blood lipid levels after the treatment,serum TC,TG,and LDL-C levels of the two groups decreased significantly ( P<0.05 ),while serum HDL-C level increased remarkably ( P<0.05 ),without significant differences between the two groups in these indexes ( P>0.05 ). Conclusion Abdominal acupuncture treatment can improve the endocrine and metabolic function of patients with obesity-type PCOS.关键词：Polycystic ovary syndrome;Abdominal acupuncture;Obesity988|1342|13更新时间：2023-08-11
- 摘要：Objective To observe the clinical therapeutic effect of acupuncture in the treatment of post-stroke depression (PSD) in the light of syndrome differentiation. Methods A total of 300 PSD patients were randomized into acupuncture group and medication group,with 150 cases in each group.For patients of acupuncture group,Sishencong (EX-HN 1),Baihui (GV 20),Shenting (GV 24),etc.were punctured combined with other acupoints according to different syndromes,once daily for 2 months.For patients of medication group,fluoxetine (20 mg/d) was administered orally,continuously for 2 months.Hamilton's depression scale (HAMD) was used to evaluate changes of PSD patients' state after the treatment. Results After the treatment,the scores of HAMD in both groups decreased significantly ( P<0.05 ),and that of acupuncture group was remarkably lower than that of medication group ( P<0.05 ). Of the two 150 PSD patients in medication and acupuncture groups,35 (23.3%) and 16 (10.7%) cases were cured,82(54.7%) and 41(27.3%)had a marked improvement,17(11.3%) and 57(38.0%) had an improvement,and 16(10.7%) and 36(24.0%) were ineffective,with the total effective rates being 89.3% and 76.0% respectively.Chi-square test showed that the therapeutic effect of acupuncture was significantly superior to that of medication group ( P<0.05 ). Conclusion Acupuncture is effective in improving post-stroke depression in PSD patients.关键词：Acupuncture therapy;Post-stroke depression;Fluoxetine1028|683|3更新时间：2023-08-11
- 摘要：Objective To determine the location of Ciliao (BL 32) by the help of three-dimensional (3-D) surface reconstruction of computed tomography (CT) so as to provide a reference for clinical application. Methods A total of 106 female volunteer subjects were enrolled in the present study. A CT scanner was used to scan the subjects' pelvis,and the collected image data was processed by Dextroscope workstation. The distances and angels of Ciliao(BL 32) in the 3-D space were measured. Results A linear correlation existed between the inter-iliac distance (L 1) and sacro-foremen distance (L 2,with the regression equation being Y=20.219+0.25X),and between the sacro-iliac distance and sacral foremen-iliac distance (with the regression equation being Y=-14.007+0.446X),which were used to determine the location of BL 32. A linear correlation also existed between the body weight and the needling depth (with the regression equation being Y=-18.893+0.988X). So,the suitably inserted straight depth of acupuncture needle could be determined according to the woman's body weight.The oblique angle of the 2 nd sacral foremen was (30.08±4.26)°,and the depth of the 2 nd sacral foramen was (20.13±2.11) mm. Conclusion In accordance with the results obtained from CT 3-D reconstruction,oblique needling of an acupuncture needle for Ciliao (BL 32) is highly recommended.关键词：Ciliao (BL 32);Location;CT 3D reconstruction;Virtual-reality technique;Acupuncture834|363|6更新时间：2023-08-11
- 摘要：When moxibustion is applied to a certain acupoint in the patient,a regional heat sensitive reaction may be found.In the present paper,the authors expound its conception and appearing regularities,its relationship with the "arrival of qi" of Chinese medicine,and its clinical application in guiding acupoint selection and heat-stimulation quantity.Heat sensitive reaction during moxibustion ( "heat sensitive moxibustion" ) is frequently seen in people undergoing pathological conditions and correlates highly with the diseases. It characterizes in dynamic changes in the location along with the state of the disorders and in being not always to coincide with the standard meridian acupoint location. The heat sensitive phenomenon of moxibustion is one of the manifestations in the activated functional activities of meridian of Chinese medicine just like the arrival of the qi caused by acupuncture stimulation.It is also a sign of activation of the human endogenous functional regulative system. Therefore,thinking highly of the heat sensitive reaction of moxibustion is the key point for raising the curative effect in clinical practice.关键词：Moxibustion therapy;Heat sensitive moxibustion;Curative effect2057|2980|49更新时间：2023-08-11
- 摘要：Migraine is a common problem in clinic,characterized by bilateral impulsive severe headache with some autonomic and neurological symptoms.Acupuncture is effective for relieving headache. In the present paper,the authors review recent development of experimental researches on the mechanism underlying acupuncture-induced improvement of migraine from:1) inhibiting neurogenic inflammation,2) improving cerebro-microcirculation,and 3) regulating vasoactive substances.The authors also point out that the theory of voltage-gated ion channel has provided a new reference for further study about the effect of acupuncture on voltage-gated ion channel of migraine animal models.关键词：Migraine;Acupuncture therapy;Animal experiments;Mechanism1173|521|1更新时间：2023-08-11
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