最新刊期

    35 5 2010
    • SHI Hong, CHENG Bin1, LI Jiang-hui, CHEN Shu-li, TAN Qi-wen1, JIN Zhi-gao, JING Xiang-hong
      Vol. 35, Issue 5, Pages: 323-329(2010) DOI: 10.13702/j.1000-0607.2010.05.001
      摘要:Objective To observe changes of mast cells(MCs) number and morphology,and substance P(SP) expression in Evans blue(EB) extravasated region around acupoint "Pishu"(BL 20) and "Weishu"(BL 21) after acute gastric mucosal injury(AGMI) so as to investigate the mechanism underlying visceral problems-induced acupoint activation.Methods Thirty adult Wistar rats were randomly divided into normal control(n=15) and AGMI groups(n=15).AGMI model was duplicated by perfusing the rats with 0.5 mol/L HCl(1 mL/100 g) after fasting for 20 h.Five hours after AGMI,the rats were treated by tail-intravenous injection of EB dye(5 mg/100 g,50 mg/mL in normal saline) for inducing dye-plasma extravasation in the skin around BL 20,BL 21 regions,etc.at the back.The rats of the normal control group were treated with tail-intravenous injection of 0.9% NaCl.The skin and subcutaneous tissues(2 mm×2 mm) of extravasated EB dye points(BL 20 or BL 21 region) and those 2 mm lateral to the extravasated EB dye points in the model group and the corresponding points in the normal control group were sampled(followed by fixing them in 4% paraformaldehyde),sectioned and stained by toluidine blue(for labeling MCs).The expression of SP in the extravasated EB dye skin and subcutaneous tissues was detected by immunohistochemistry(n=5) and western blot(n=5) respectively.The number of MCs in these samples was counted and the degranulation rate of MCs calculated.Results The total number of MCs and the number of degranulated MCs were significantly more in the EB extravasation points(correspon-ding to BL 20/BL 21 area) of AGMI group than those in the control spots of AGMI group and than those in the normal control group(P<0.05,P<0.001).The degranulation rate of MCs was significantly higher in the EB extravasation points of AGMI group than those in the control spots of AGMI group and in the normal control group(P<0.01).In comparison with normal control group,the SP expression level was increased consideraly in the control spots of AGMI group and AGMI group(P<0.01).Conclusion After AGMI,the numbers of MCs and the degranulated MCs,and the SP expression level in BL 20/BL 21 area were increased signi-ficantly,suggesting an involvement of MCs and SP in the process of AGMI-induced activation of acupoints.  
      关键词:Acute gastric mucosal injury;Acupoint sensitization;Neurogenic inflammation;Mast cells;Substance P expression   
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    • DAI Wei, LI Wei-dong, LU Jun, TU Ya
      Vol. 35, Issue 5, Pages: 330-334(2010) DOI: 10.13702/j.1000-0607.2010.05.002
      摘要:Objective To observe the effect of electroacupuncture(EA) on hippocampal apoptosis and c-Jun N-terminal kinase(JNK) signal pathway in chronic stress depression rats so as to study its mechanism underlying acupuncture-induced improvement of depression.Methods Sixty-five SD rats were randomly divided into control,control+EA,model,EA and Prozac groups,with 13 rats in each.Open-field test was used to detect the rats' behavior changes.The apoptotic rate of the hippocampal cells was detected by Annexin V fluorescein isothiocyanate(FITC)/ Propidium iodide(PI)(Annexin V-FITC/PI) double-staining,and the expression of hippocampal JNK protein detected by Western blot.Results After repeated stress stimulation(21 days),the crossing numbers(1.8±0.2) and rearing times(0.5±0.1) in the model group were apparently lower than those(48.1±18.3,14.2±2.4)in the control group and those(47.2 ±15.8,13.5±2.6)in the control+EA group(P<0.05).Compared with the model group,the crossing numbers and rearing times(40.2±10.1,10.3±2.2) during 3 min in the EA group and those(39.8±12.4,10.6±3.2) in the Prozac group were increased considerably(P<0.05).The hippocampal apoptotic rate was significantly higher in the model group(67±10) than in the control(53±13) and control+EA groups(52±10,P<0.05).In comparison with the model group,the apoptotic rate(29±9) of the EA group and that(51±13) of the Prozac group were significantly lower(P<0.05).Compared with the control group,the phosphorylated JNK(p-JNK) level was considerably higher in the model group(P<0.05);while compared with the model group,the p-JNK level was significantly lower in the EA and Pozac groups(P<0.05).No apparent differences were found between the EA and and Prozac groups in the aforementioned indexes(P>0.05).Conclusion EA can reduce hippocampal apoptotic rate and down-regulate hippocampal p-JNK level in depression rats,which is responsible for its effect in improving depression-induced decreased movement.  
      关键词:Electroacupuncture;Depression;Chronic stress;Hippocampus;Apoptosis;p-JNK level   
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    • CHEN Shu-ping, GAO Yong-hui, YU Xiao-chun1, LIU Jun-ling
      Vol. 35, Issue 5, Pages: 335-341(2010) DOI: 10.13702/j.1000-0607.2010.05.003
      摘要:Objective To observe the influence of electroacupuncture(EA) of different acupoints on changes of mean arterial pressure(MAP),heart rate(HR) and heart rate variability(HRV) in colorectal distension(CRD) rats,so as to analyze the specificity of actions of acupoints in relieving visceral pain and regulating activities of the autonomic nerve system.MethodsForty-five Wistar rats were randomized into control,Zusanli(ST 36),non-acupoint,Neiguan(PC 6) and Taichong(LR 3) groups(n=9/group).Under anesthesia,CRD was given to the rats by using an aerostat for 5 min.EA(2 Hz/15 Hz,2 mA) was applied to bilateral ST 36,non-acupoint(1.0 cm lateral to ST 36),PC 6 and LR 3 for 15 min,respectively.Electrocardiogram of the cervico-chest lead was recorded by using a bioelectric amplifier,and MAP recorded by using a pressure transducer and an amplifier.Low frequency and high frequency of HRV were analyzed by Chart 5.0.Results Following CRD,the HR,MAP,LF and LF/HF levels increased significantly in all the 5 groups(P<0.05),while HF had no apparent changes(P>0.05).Compared with the control group,5 min and 15 min after EA,and 10 min after ceasing EA,MAP values of ST 36 and PC 6 groups were decreased obviously(P<0.05).The HR values of ST 36 and PC 6 groups at 15 min after EA and 10 min after ceasing EA were decreased markedly in comparison with those of each of the other groups during CRD(P<0.05).The LF levels of both ST 36 and PC 6 groups at 5 min after EA,and those of ST 36,PC 6 and LR 3 at 15 min after EA were significantly lower than those of control group(P<0.05).LF/HF levels of ST 36 and PC 6 at 10 min after ceasing EA were obviously lower than those of control group(P<0.05).No significant differences were found among ST 36,non-acupoint,PC 6 and LR 3 groups in HR,LF and LF/HF(P>0.05).Conclusion EA of ST 36 and PC 6 can suppress CRD-induced increase of MAP,HR and LF/HF,suggesting beneficial effects of EA in relieving visceral pain and mediating autonomic nerve system.The aforementioned effects of EA of LR 3 and non-acupoint are not obvious.  
      关键词:Colorectal distension;Heart rate variability;Mean arterial pressure;Electroacupuncture;Zusanli(ST 36);Taichong(LR 3);Neiguan(PC 6)   
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    • SONG Xiao-lin, ZHANG Lu-fen, Li Xiao-hong, XU Li-li, LI Chun-hua, DING Xi-yan, REN Xiao-xuan, ZHAO Ya-fang, GUO Meng-wei, SUN Zhi-fang, ZHU Jiang
      Vol. 35, Issue 5, Pages: 342-346(2010) DOI: 10.13702/j.1000-0607.2010.05.004
      摘要:Objective To investigate the effect of electroacupuncture(EA) of "Sanyinjiao"(SP 6) on the uterus in dysmenorrhea rats so as to study its underlying analgesic mechanism.Methods A total of 48 SD rats during diestrus were randomized into normal saline(control) group,model group and acupuncture group according to a random number table,with 16 rats in each group.Dysmenorrhea model was established by subcutaneous injection of Estradiol benzoate(0.5 mg/d on the 1st and 10th day,and 0.2 mg/d from day 2 to day 9,once daily for 10 days) and oxytocin(2 U/rat,once on day 10).Malondialdehyde(MDA) and β-endorphin(β-EP) contents in the uterus were detected by radioimmunoassay,and the heat shock protein 70(HSP 70) immunoactivity of the uterus was detected by immunohistochemistry.Results In comparison with the control group,MDA content in the uterus was increased significantly in the model group(P<0.01),while the β-EP level and the immunoactivity of HSP 70 immuno-reaction(IR) positive products in the uterus decrease significantly(P<0.01)and moderately,respectively in the model group.In comparison with the model group,uterine MDA content in the EA group was decreased significantly(P<0.01),while uterine β-EP level increased considerably(P<0.01)and HSP 70 expression was upregulated to a certain degree.Conclusion EA of "Sanyinjiao"(SP 6) can reduce MDA content and upregulate β-EP level of the uterus in rats with dysmenorrhea,which may contribute to its analgesic effect in relieving dysmenorrhea by clearing away oxygen free radicals and raising analgesic substance in the uterus.  
      关键词:Electroacupuncture;Sanyinjiao(SP 6);Dysmenorrhea;Uterus;MDA;β-endorphin;Heat shock protein 70 expression   
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    • REN Xiu-jun, MA Hui-fang, TU Ya
      Vol. 35, Issue 5, Pages: 347-353(2010) DOI: 10.13702/j.1000-0607.2010.05.005
      摘要:Objective To observe the effects of electroacupuncture(EA) on the expression of vimentin and β-Tubulin(Tju-1) in the dorsolateral extension and the lateral wall of the lateral ventricle(both of which belong to the subependymal ventricular zone,SVZ) on the ischemic side of the brain in rats with hyperlipemia(HL) plus cerebral ischemia(CI) so as to study its underlying mechanism in relievting HL,CI and combined HL and CI by regulating the proliferation and differentiation of neural stem cells.Methods Seventy two male SD rats were randomized into control,HL,HL+ EA,CI,CI+manual acupuncture(MA),HL+CI,HL+CI+EAⅠ and HL+CI+EAⅡgroups,with 9 cases in each.HL model was established by feeding the animals with high fat forage for 6 weeks and CI model was duplicated by occlusion of the unilateral middle cerebral artery induced by regional application of FeCl_3.For rats of HL+EA group,EA(15 Hz,1-3 mA) was applied to bilateral "Sanyinjiao"(SP 6) and "Fenglong"(ST 40) for 20 min,once daily for 17 days.For rats of CI+MA group,"Baihui"(GV 20) and "Shuigou"(GV 26) were punctured and stimulated manually for 1 min(the former with the needle retained for 20 min),once daily for 7 days.For rats of HL+CI+EAⅠ group,bilateral "Sanyinjiao"(SP 6) and "Fenglong"(ST 40) were stimulated electrically after needle-insertion,once daily for 10 days,followed by duplicating CI model and performing MA stimulation of GV 20 and GV 26 respectively,once daily for 7 days.For rats of HL+CI+EAⅡgroups,EA was applied to bilateral SP 6 and ST 40,and simultaneous MA stimulation of GV 20 and GV 26,once daily for 7 days after HL+CI.The expression of vimentin and Tuj-1 in the dorsolateral extension and the lateral wall of the cerebral lateral ventricle on the ischemic side was detected by immunohistochemistry.Results Compared with the control group,the expression levels of both vimentin and Tuj-1 in the dorsolateral extension and the lateral wall of the lateral ventricle of the brain on the ischemic side were increased significantly in the CI and HL+CI groups(P<0.01),while compared with the CI group,the expression of vimentin and Tuj-1 in the CI+MA group were increased further significantly(P<0.01).In comparison with the HL+CI group,the expression of vimentin and Tuj-1 in the HL+CI+EAⅠ and HL+CI+EAⅡ groups were also upregula-ted considerably(P<0.01).Comparison between the HL+CI+EAⅠ and HL+CI+EAⅡ groups showed that the expression le-vels of vimentin and Tuj-1 were significantly lower in the latter group than in the former group(P<0.01).No significant diffrences were found between the HL and control groups,and between the HL and HL+EA groups in the expression of vimentin and Tuj-1(P>0.05).Conclusion Acupuncture and Acupuncture+EA can further significantly upregulate the expression levels of vimentin and Tuj-1 in both the dorsolateral extension and the lateral wall of the cerebral lateral ventricle on the ischemic side in rats with CI and CI+HL,which may contribute to their effects in improving CI and HL+CI by suppressing the reduction of proliferation and differentiation of neural stem cell in the SVZ of the ischemic brain induced by CI and HL+CI.  
      关键词:Electroacupuncture;Hyperlipemia with cerebral ischemia;Vimentin;Tuj-1;Subventricular zone   
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    • Vol. 35, Issue 5, Pages: 354-358(2010) DOI: 10.13702/j.1000-0607.2010.05.006
      摘要:Objective To observe the effect of acupotomy lysis(AL) on hypothalamic proopiomelanocortin(POMC) mRNA and preproenkephalin(PPE) mRNA expression in rats with the third lumbar vertebrae transverse process syndrome(TLVTPS) so as to study its underlying mechanism in relieving symptoms of lumbar muscle strain.Methods Twenty-four SD rats were randomly divided into normal control group,model group,AL group and electroacupunture(EA) group.The TLVTPS model was established by inserting a piece of gelatin sponge into the posterior of the left 3rd lumbar vertebrae transverse process.AL and EA were applied to the left "Shenshu"(BL 23) and "Yaoyangguan"(GV 3) respectively.The POMC mRNA and PPE mRNA expression levels in the hypothalamus were detected by in situ hybridization.Results In comparison with the normal group,the integrated optical density(IOD) values of hypothalamic POMC mRNA and PPE mRNA positive cells in the model group were increased significantly(P<0.01);while compared with the model group,those of POMC mRNA and PPE mRNA positive cells in both left and right hypothalamus were increased further considerably in both AL and EA groups(P<0.01).No significant diffe-rences were found between AL and EA groups in POMC mRNA and PPE mRNA expression levels(P>0.05).Conclusion AL and EA therapies can increase the expression of POMC mRNA and PPE mRNA in hypothalamus in rats with TLVTPS,which may contribute to its effect in relieving pain in the treatment of lumbar muscle strain.  
      关键词:Third lumbar vertebrae transverse process syndrome;Acupotomy lysis;Electroacupuncture;Hypotha-lamus;POMC mRNA;PPE mRNA   
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    • GU Yi-huang, REN Jian-ning1, WU Yun-chuan, LI Shou-dong, SHI Shu-sheng2
      Vol. 35, Issue 5, Pages: 359-362(2010) DOI: 10.13702/j.1000-0607.2010.05.007
      摘要:Objective To observe the influence of acupuncture on the motor ability of training-induced fatigue mice so as to explore its mechanism underlying acupuncture-induced improvement of physical training fatigue.Methods Sixty Kunming mice were divided into normal control,training model and acupuncture groups,with 20 mice in each.The training-fatigue model was established by forcing the mouse to swim in a water tank for 30 min/d in the 1st week,60 min/d in the 2nd week,90 min/d in the 3rd week and 120 min/d in the 4th and 5th weeks."Guanyuan"(CV 4),and bilateral "Zusanli"(ST 36) and "Shenshu"(BL 23) were punctured with filiform needles,and with the needle twirled for about 30 s and retained for 5 min.The treatment was conducted once daily for 2 weeks.The duration of exhaustion training was recorded.Serum lactic acid(LA),lactate dehydrogenase(LDH) and creatine kinase(CK) contents were detected by LA oxidase method,immuno-suppressive assay and enzyme-linked immunoassay,respectively.Results Compared with the training-fatigue(model) group,the duration of the exhausted swimming of the acupuncture group was obviously longer(P<0.05).In comparison with the control group,serum LA,LDH and CK contents were increased considerably in the model and acupuncture groups(P<0.05,P<0.01),while compared with the model group,serum LDH level of acupuncture group was increased significantly(P<0.05),and serum CK level of acupuncture group decreased obviously(P<0.05).No significant difference was found between the model and acupuncture groups in serum LA content(P>0.05).Conclusion Acupuncture can effectively improve the motor ability of the training-fatigue mice,which may be closely relevant to its effects in upregulating LDH activity and reducing serum CK.  
      关键词:Acupuncture;Training fatigue;Motor ability;Serum LA;LDH;CK   
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    • HU Ling, HE Lu, CAI Rong-lin, LONG Di-he, WU Zi-jian
      Vol. 35, Issue 5, Pages: 363-367(2010) DOI: 10.13702/j.1000-0607.2010.05.008
      摘要:Objective To observe the effects of electroacupuncture(EA) of "Source-"+"Collateral-"acupoints ["Shenmen"(HT 7)+"Zhizheng"(SI 7)] and single acupoints "Neiguan"(PC 6)and HT 7 on cardiac function and myocardial enzymes in acute myocardial ischemia(AMI)rabbits.Methods Sixty Chinchilla rabbits were randomized into normal control,model,Shenmen(HT 7),Neiguan(PC 6),HT 7+SI 7 groups,with 8 rabbits in each.AMI model was duplicated by occlusion of the anterior descending branch of left coronary artery under anesthesia.EA(2 Hz,1 mA)was applied to acupoints HT 7,PC 6,and HT 7+SI 7 for 10 min.The maximum ascending rate(+dp/dt max) and maximum descending rate(-dp/dt max)of the left ventricular pressure(LVP)were recorded by using PowerLab System.Serum lactate dehydrogenase(LDH)and creatine kinase MB(CK-MB)contents were detected with chromatometry.Results Serum LDH and CK-MB contents increased significantly in model group than in normal control group(P<0.01).Compared with model group,serum LDH and CK-MB contents decreased remarkably in PC 6,HT 7 and HT 7+SI 7 groups(P<0.01,P<0.05),and the effects of HT 7+SI 7 group were significantly superior to those of PC 6 and HT 7 groups in lowering serum LDH and CK-MB levels(P<0.01,P<0.05).Compared with the normal control group,+dp/dt max lowered significantly and-dp/dt max increased markedly in the model group(P<0.01),while compared with the model group,+dp/dt max increased obviously and-dp/dt max decreased significantly in the three EA groups(P<0.01,P<0.05).The effects of HT 7+SI 7 group were markedly superior to those of HT 7 and PC 6 in raising +dp/dt max and lowering-dp/dt max(P<0.05,P<0.01),and those effects of PC 6 group were evidently better than those of HT 7 group(P<0.05,P<0.01). Conclusion EA of "Source-"+"Collateral-"acupoints(HT 7+SI 7),HT 7 and PC 6 has a positive effect in improving changes of cardiac function and in lowering serum LDH and CK-MB contents in AMI rabbits,and the effect of EA of HT 7+SI 7 is superior to that of EA of single acupoint.  
      关键词:Source-collateral acupoints combination;Electroacupuncture;Neiguan(PC 6);Shenmen(HT 7);Zhizheng(SI 7);Cardiac function;Myocardial enzyme   
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    • AN Li-xin, LI Jin, REN Xiu-jun1, LIU Yun-ning2, WANG Bao-guo
      Vol. 35, Issue 5, Pages: 368-374(2010) DOI: 10.13702/j.1000-0607.2010.05.009
      摘要:Objective To observe the effect of electroacupuncture(EA) of different acupoint groups on the sevoflurane anesthetic requirement for resection of supratentorial tumors and the speed of post-operation recovery.Methods A total of 120 cases of supratentorial tumor resection patients were randomly and equally allocated into general anesthesia(GA) group,EA-proximal acupoints group(EA-PA group) and EA-distant acupoints group(EA-DA group).The supratentorial tumor patients were anesthetized with sevoflurane for surgery.Proximal acupoints used were Fengchi(GB 20),Tianzhu(BL 10),Cuanzhu(BL 2) and Yuyao(EX-HN 4) that the former 2 acupoints and the latter 2 acupoints were for penetrative needling;and distant acupoints used were Hegu(LI 4),Waiguan(TE 5),Jinmen(BL 63),Taichong(LR 3),Zusanli(ST 36) and Qiuxu(GB 40) on the craniotomy side,and stimulated with EA(2 Hz/100 Hz,a tolerable electric stimulating strength),beginning from the anesthesia induction till the end of surgical operation.All patients were anesthetized by inhalation of propofol(2 mg/kg),sufentanil(0.3 μg/kg) and vecuronium bromide(0.1 mg/kg) and maintained with sevoflurane.The end-tidal sevoflurane concentration,minimum alveolar concentration(MAC),bispectral index(BIS),and the speed of recovery were recorded.Results In comparison with the GA group,the end-tidal concentrations during anesthesia maintenance at the time-points of post skull drilling,dura incising,intracra-nial operation in EA-PA group,the time-points of post skull drilling,skull opening,dura incising,and intracranial operation in EA-DA group,and the MAC of sevoflurane at the time-points of skull drilling in EA-DA group,and skull opening,dura incising,intracranial operation and dura suturing in both EA-PA and EA-DA groups were significantly lower(P<0.05,P<0.01).Compared to the GA group,the BIS values of EA-DA group at the time-points of skull drilling and opening,and dura incising were significantly higher(P<0.05),while during the recovery stage of anesthesia,in comparison with the GA group,the autonomous respiration recovery time,tracheo-tube removing time,eye-opening time,voluntary motion recovery time,orientation force recovery time,and operating room-departure time of both EA-PA and EA-DA groups were significantly shorter(P<0.05,P<0.01).No significant differences were found between the EA-PA and EA-DA groups in the aforementioned indexes(P>0.05).Conclusion EA of both proximal and distant acupoints can reduce the expired concentration and MAC of sevoflurane during anesthesia maintenance,and accelerate the recovery after cease of anesthesia in supratentorial tumor resection patients.  
      关键词:Supratentorial tumor resection;Sevoflurane;Electroacupuncture;Proximal and distant acupoint groups;General anesthesia;Acupuncture-assistant anesthesia   
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    • WANG Cheng-wei, LI Ning, HE Hong-bo, Lü Jian-qin, LIU Zhi-shun1
      Vol. 35, Issue 5, Pages: 375-379(2010) DOI: 10.13702/j.1000-0607.2010.05.010
      摘要:Objective To observe the effects of electroacupuncture(EA) of Tianshu(ST 25) and medication on the subjective symptoms and the satisfactory degree of functional constipation(FC) patients,and to evaluate the efficacy of different depth-needling.Methods Single-blind,randomized and parallel-controlled methods were adopted in the present study and a total of 95 FC patients were randomly divided into medication group(Lactulose,20-30 mL/d,n=24),deep needling(DN,about 45 mm beneath the skin) of ST 25 group(n=48),and shallow needling(SN,about 5 mm beneath the skin) of ST 25 group(n=23).The treatment was given once daily(except weekends) for 4 weeks.The actual number of patients whose defecation frequency was up to 4 times per week,the integrative score of defecation symptoms(defecation exertion degree,abdominal pain,etc.),and the patients' satisfaction degree after the treatment were recorded and evaluated.Results One,2,3 and 4 weeks after the treatment,of the 48,23 and 24 cases in DN,SN and medication groups,the numbers of FC patints whose defecation was up to 4 times per week were 31(64.58%),32(66.67%),34(70.83%) and 37(77.08%),9(39.13%),16(69.57%),15(65.22%) and 14(60.87%),and 8(33.33%),7(29.17%),5(20.83%) and 4(16.67%),respectively.The effects of DN and SN groups were significantly superior to those of medication group in increasing the number of FC patints whose defecation was up to 4 times per week,improving constipation symptom integrative score(defecation exertion degree,survival desire for defecation,abdominal distension,etc.) and patients' satisfaction degree(P<0.05).Comparison between DN and SN groups showed that the effects of the former group in accelerating the improvement of survival desire for defecation,patients' satisfaction degree were markedly superior to those of the latter group(P<0.05).Conclusion Deep needling-EA of ST 25 has a positive effect in improving functional constipation,being faster in the onset of action and stable efficacy in comparison with shallow needling.  
      关键词:Functional Constipation;Deep needling;Electroacupuncture;Tianshu(ST 25);Randomized controlled trials   
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    • ZHOU Yuan, ZHOU Guo-ying1, LI Shao-kun2, JIN Jian-hong3
      Vol. 35, Issue 5, Pages: 380-383(2010) DOI: 10.13702/j.1000-0607.2010.05.011
      摘要:Objective To observe the therapeutic effect of electroacupuncture(EA) combined with cupping at the lumbo-back on post-stroke fatigue.Methods A total of 128 cases of post-stroke fatigue patients were randomly divided into EA+cupping group and medication group,with 64 cases in each group.EA(20 Hz,2 mA) was applied to Baihui(GV 20),Yintang(EX-HN 3),Shuigou(GV 26),Hegu(LI 4),Zusanli(ST 36),Sanyinjiao(SP 6),and Taichong(LR 3) for 30 min,once daily for 30 times,and cupping was applied at the patient's lumbo-back region once every two days,and continuously for 5 weeks.Patients of medication group were ordered to take compound aminobutyric acid vitamin E capsule(20 mg,t.i.d,po),magnesium gluconate solution(10 mL,t.i.d,po),sertraline hydrochloridetablet(50 mg,qd,po)for 5 weeks.The Stroke Specific Quality of Life Scale(SS-QOL) was used to evaluate the patients' energy state.Results After the treatment,the energy scores of SS-QOL of both EA+cupping and medication groups were increased significantly in comparison with the pre-treatment in each group(P<0.05),and that of the EA+cupping group was significantly higher than the score of the medication group(P<0.05).Of the two 64 cases in EA+cupping group and medication group,42 and 23 were recovered basically,13 and 13 experienced marked improvement,7 and 18 were effective,2 and 10 failed in the treatment,with the effective rates being 96.87% and 84.37% respectively.The effective rate of EA+cupping group was obviously higher than that of medication group(P<0.01).Conclusion EA+ cupping at the lumbo-back can effectively relieve fatigue of post-stroke patients,and its therapeutic effect is superior to medication.  
      关键词:Electroacupuncture;Cupping;Post-stroke fatigue;Medication   
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    • LIU Tang-yi, YANG Hua-yuan, GAO Ming, XU Gang, TANG Wen-chao
      Vol. 35, Issue 5, Pages: 384-387(2010) DOI: 10.13702/j.1000-0607.2010.05.012
      摘要:In current clinical acupuncture practice,many exiting problems including changes in the treated region,simultaneous covering two meridians of the two stimulating electrodes(acupuncture needles),inability to realize the reinforcing-reducing functions of the traditional acupuncture,etc.during application of electroacupuncture(EA) could be found,which may affect the therapeutic results or lead to failure in playing EA's functions.For this reason,the authors of the present paper put forward a concept of "single acupoint EA".Base on the design of "double electrodes of two acupuncture needles" of the conventional EA therapeutic apparatus,a "single acupoint EA therapy" was put forward and a single acupoint EA electronic apparatus(stimulating needle electrode) was manufactured.It not only realizes single acupoint stimulation,but also corresponds to the features of traditional EA therapy,avoiding some problems in currently-used EA therapy.It may be helpful to raising clinical therapeutic effect.  
      关键词:Electroacupuncture apparatus;Single-acupoint electronic apparatus;Single-acupoint electrical therapeutics   
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    • ZHAO Jing-sheng
      Vol. 35, Issue 5, Pages: 388-390(2010) DOI: 10.13702/j.1000-0607.2010.05.013
      摘要:It is generally acknowledged that "tender-point is taken as the acupoint"(tender-point) and "Ashi-point" belong to the same one concept.Through a series of research and analysis,it was found that these two nomenclatures contain both identical and different points in connotation,and reflect different experience in the treatment of abundant clinical conditions."Tender-point" is involved in the general experience,for which the affected site is punctured directly by using an acupuncture needle or stimulated by using a moxa-stick or moxa-cone."Ashi-point" is referred to the regional reactive site,i.e.,the sensitive point for acupuncture and moxibustion,which is involved in the specific experience for taking the reactive point of clinical problems as the therapeutic site.The so-called "Tianying-point" and "Buding-point" in classical books on acu-moxibustion as Qian-jin Fang(Prescriptions Worth a Thousand Gold for Emergencies),Yulong Ge(Lyrics of Jade Dragon),etc.,are the same to "Tender-point" but different to "Ashi-point".Currently,explanations and clinical application about "Tender-point" have been generalized and mixed up with "Ashi-point".The author of the present paper makes an analysis on their causes.  
      关键词:"Tender-point";"Ashi-point";Concept and Nomenclature   
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    • SUI Ming-he, MA Hui-fang, WANG Chao-yang
      Vol. 35, Issue 5, Pages: 391-393(2010) DOI: 10.13702/j.1000-0607.2010.05.014
      摘要:The four acupoints Fushe(SP 13),Fujie(SP 14),Daheng(SP 15) and Fuai(SP 16)(except SP 12) of the Spleen Meridian of Foot-Taiyin in the abdomen are all 4 cun lateral to the abdominal midline.The origin of "4-cun" distance and the related explanations have not been found in any books including textbooks and related Chinese national standards about acupuncture and moxibustion.In the graphical representations,these 4 acupoints are directly below the nipple,because the nipple is 4 cun from the chest midline.The authors of the present paper don't think that is right,because in locating the acupoint,the nearest body surface anatomical landmarks should be used first as the basis.The abdomen and the chest are two anatomic sites after all,locating the abdominal acupoints with the chest surface landmarks often results in larger deviation,because many people's bodies are not so symmetrical and standard,and the adult abdominal fat difference is very big.Therefore,it is highly recommended that the abdominal acupoints are located by using the abdominal anatomical landmarks,for example,the outer edge of rectus abdominis,the outer edge of abdomen,etc.  
      关键词:Acupoints;Location;Discussion   
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    • DU Yuan-hao, XIONG Jun1, XU Yan-long1, LI Bo1, SUN Pan1, GAO Xiang1, CHEN Yuan-wu1
      Vol. 35, Issue 5, Pages: 394-401(2010) DOI: 10.13702/j.1000-0607.2010.05.015
      摘要:Objective To determine the graded-disease-spectrum of the nervous system of acu-moxibustion treatment based on its clinical efficacy.Methods We carried out a cross-sectional academic sample investigation on the graded-disease-spectrum of acu-moxibustion by collecting and analyzing data from the self-administered questionnaires which were completed by professional persons who have high-ranking professional titles(associate chief physicians and chief physicians) and are majoring in acupuncture and moxibustion.Then,the collected experts' opinions were analyzed by fuzzy comprehensive estimation technique and statistical processing.Results A total of 58 medical conditions involving 4 grades and 126 subtypes were included and analyzed.The Grade Ⅰ contains 14 subtypes as Bell's palsy(in the acute stage and convalescence stage),primary sciatic neuralgia,migraine(mild type and moderate type),etc.which can be relieved by using acu-moxibustion therapy only.The Grade Ⅱ contains 53 subtypes,such as transient cerebral ischemic attack,acute cerebrovascular disease(in the convalescence stage and sequelae stage),chronic Bell's palsy(sequelae),Hunt's facial palsy,etc.which can be relieved by using acu-moxibustion as the main therapy.The Grade Ⅲ contains 22 subtypes,such as acute stage of ischemic cerebrovascular disease(with coma and without coma),acute stage of hemorrhagic ischemic cerebrovascular disease(with coma and without coma),etc.which may be relieved to a certain degree by using acu-moxibustion as the supplementary or main therapy.The Grade Ⅳ contains 37 subtypes,such as Wohlfart-Kugelberg-Welander disease,myasthenia gravis(type Ⅲand type Ⅳ),myasthenia gravis of medicinal herbs resource,chorea major,etc.whose clinical effects are not known if treated with acu-moxibustion.Conclusion Acu-moxibustion therapy has apparent advantages in the treatment of different clinical conditions of the nervous system.  
      关键词:Diseases of the nervous system;Graded-disease-spectrum/efficient of acu-moxibustion therapy;Questionnaire survey;Fuzzy comprehensive estimation technique   
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