最新刊期
卷 38 ， 期 1 ， 2013
- 摘要：Objective To observe the effect of electroacupuncture(EA) combined with cervical plexus block(CPB) on the stress response of patients undergoing thyroid surgery.Methods Forty thyroidectomy patients were randomly divided into sham EA plus CPB group(sham group) and EA+CPB group(20 cases in each group).For patients of the sham group,deep cervical plexus block(25% ropivacaine hydrochloride + 1% lidocaine hydrochloride) was performed first,followed by inserting acupuncture needles into bilateral Hegu(LI 4) and Neiguan(PC 6)separately without needle manipulation and then connecting the output wires of the EA therapeutic instrument to the handles of the acupuncture needles but without electric current output.For patients of the EA+CPB group,deep cervical plexus block was performed first followed by EA stimulation [10 Hz,(6±2) mA] of the bilateral LI 4 and PC 6 for 20 min.Systolic blood pressure(SBP),heart rate(HR) and breathing frequency were detected using a multipurpose monitor.Plasma adrenocorticotropic hormone(ACTH) and cortisol(Cor) contents were determined using chemiluminescence method,plasma epinephrine(E) level was detected by enzyme-linked immunosorbent assay,glucose(Glu) assayed by oxidase method,and plasma C-reactive protein(CRP) level detected using immumofluorescence technique.Results(1) During surgery,the patients' SBP and HR of both sham and EA groups were increased significantly compared with their basic values(P<0.05),but the levels of the increased SBP and HR of the EA group were obviously lower than those of the sham group(P<0.05).(2) The levels of plasma ACTH during surgery and at the immediate time after surgery,Cor level at the immediate time after surgery,plasma E and Glu contents during surgery,at the immediate time and on day 1 after surgery,and plasma CRP at the immediate time,and on day 1 and 3 after surgery in the sham group were upregulated considerably(P<0.05),while the levels of plasma ACTH,Cor,E,Glu and CRP in the above-mentioned time-points of the EA group were all remarkably lower than those of the sham group(P<0.05).Conclusion EA combined with cervical plexus block significantly reduces peri-operative cardiovascular stress responses and inhibits abnormal increases of plasma stress hormones and inflammatory reaction in patients undergoing thyroid surgery.关键词：Electroacupuncture analgesia;Thyroid surgery;Cervical plexus block;Stress responses993|302|8更新时间：2023-08-11
- 摘要：Objective To observe the effect of electroacupuncture(EA) of auricular concha region(ACR),"Zusanli"(ST 36) and "Sanyinjiao"(SP 6) on abnormal skin barrier and color in streptozotocin(STZ)-induced type 2 diabetes mellitus(T 2 DM) rats so as to find a better therapeutic method.Methods Fifty male Sprague Dawley(SD) rats were randomized into control(n=10),model(n=13),EA-ST 36-SP 6(n=14) and EA-ACR(n=13) groups.T 2 DM model was established by intra-peritoneal injection of 1% STZ(50 mg/kg) and by feeding the animals with high-fat diet for 30 days.EA(15 Hz,1 mA) was applied to bilateral "Zusanli"(ST 36),"Sanyinjiao"(SP 6) and ACR respectively for 30 min,once daily for 14 days.Multi Probe Adapter 9 skin measurement system(MPA 9) was used to measure the stratum corneum hydration(SCH),transepidermal water loss(TEWL),erythema index(EI),melanin index(MI) and chromatic aberration values(L.a.b.) of the abdomenal and back(L1-L6) skin,respectively.Results In comparison with the control group and pre-modeling,blood glucose contents of the mo-del,EA-ST 36-SP 6 and EA-ACR groups were increased significantly(P<0.01) after modeling.Compared with the model group,blood glucose levels of both EA-ST 36-SP 6 and EA-ACR groups were down-regulated apparently(P<0.01) after treatment.Thirty days after modeling,the SCH,TEWL,EI,MI,L.and a.levels of the back skin,and the SCH and L.levels of the abdominal skin were decreased significantly(P<0.05),while the level of b.in the back skin,and those of TEWL,EI,a.and b.of the abdominal skin increased considerably in the model group(P<0.05).After EA,the levels of SCH,TEWL MI,L.a.and b.in the EA-ST 36-SP 6 group,SCH,TEWL,L.and b.in the EA-ACR group of the back skin,and SCH,L.and b.of both EA-ST 36-SP 6 and EA-ACR groups,as well as EI and a.of the EA-ST 36-SP 6 group of the abdominal skin were reversed remar-kably(P<0.05).No significant differences were found between the EA-ST 36-SP 6 and model groups in the levels of EI of the back skin,TEWL and MI of the abdominal skin,and between the EA-ACR and model groups in the levels of SCH,EI,MI and a.of the back skin,and TEWL,EI,MI and a.of the abdominal skin(P>0.05).In spite of a mildly better therapeutic effect of EA-ST 36-SP 6 in regulating some of the abovementioned indexes,no significant differences were found between the two EA groups in all the indexes(P>0.05).Conclusion EA of both ST 36-SP 6 and ACR can effectively down-regulate blood glucose level,suppress DM-induced decrease of SCH,TEWL,L.and a.of the back skin,and SCH of the abdominal skin,and down-regulate b.levels of the back and abdominal skin in T 2 DM rats,showing an improvement of the impaired skin barrier and color changes following EA intervention.关键词：Electroacupuncture;Type 2 diabetes mellitus;Streptozotocin-induced rat;Skin;Auricular concha region1437|349|1更新时间：2023-08-11
- 摘要：Objective To observe the effect of moxibustion of "Dachangshu"(BL 25) on pain reaction and expression of transient receptor potential vanilloid 1(TRPV 1) of bone marrow cells in visceral hyperalgesia(VHA) rats so as to explore its mechanism underlying visceral pain-relief.Methods Twenty-eight male SD rats were divided into control group,control+mo-xibustion group,VHA model and VHA+moxibustion group(n=7/group).The VHA model was made by giving colorectal distension(CRD,60 mmHg) to the newborn rats for 1 min(repeated once again in 30 min) from postnatal day 8 on,once daily for a week.Moxibustion was applied to ipsilateral "Dachangshu"(BL 25) area for 40 min from the 8th week on after birth.Abdominal withdrawal reflex(AWR) and pain threshold during CRD were measured before and after moxibustion.The TRPV 1 mRNA expression of bone marrow cells was detected by real time-PCR.Results ① The AWR score of the model group was significantly higher than that of the control group,but the pain threshold of the model group was significantly lower than that of the control group(P<0.01),suggesting a VHA in model rats.② After moxibustion,the AWR scores were significantly lower in the VHA+moxibustion group than in the model group(P<0.05,P<0.01),and the pain threshold was remarkably higher in the former group than in the latter group(P<0.01).Similar results were found in the control+moxibustion group compared to the control group: the decreased AWR scores(CRD 40 mmHg,60 mmHg and 80 mmHg,P<0.01) and the increased pain threshold(P<0.05).③The TRPV 1 mRNA expression level of bone marrow cells was significantly lower in the VHA+moxibustion group than in the model group(P<0.01).No significant difference was found between the control and moxibustion+control groups in TRPV 1 mRNA expression level(P>0.05).Conclusion Moxibustion of "Dachangshu"(BL 25) can reduce visceral hyperalgesia and down-regulate TRPV 1 mRNA expression of bone marrow cells in VHA rats,suggesting an involvement of TRPV 1 mRNA of bone marrow cells in CRD-induced visceral pain development.关键词：Visceral hyperalgesia;Moxibustion intervention;Dachangshu(BL 25);Transient receptor potential vanilloid 1(TRPV 1);Bone marrow cells;Colorectal distension1685|658|4更新时间：2023-08-11
- 摘要：Objective To observe the protective effect of acupuncture stimulation on pyramidal cells in hippocampal CA 1 and CA 3 regions and to analyze the involvement of phosphatidy linositol-3-kinase(PI 3 K) /protein kinase B(PKB or Akt)signaling pathway in the acupuncture effect in epilepsy rats.Methods A total of 120 SD rats were randomly divided into normal control group,model group,LY 294002(a specific antagonist for PI 3 K/Akt signaling) group,acupuncture+LY 294002 group and acupuncture group(n=24 in each group,12 for H.E.staining,and 12 for electron microscope observation).Epilepsy model was established by intraperitoneal injection of pentylenetetrazol(PTZ,5 μL).Manual acupuncture stimulation was applied to "Baihui"(GV 20) and "Dazhui"(GV 14) once daily for 5 days.Dimethyl Sulfoxide(DMSO,5 μL,a control solvent) was given to rats of the normal,model and acupuncture groups,and LY 294002(5 μL,dissolved in DMSO) given to rats of the LY 294002 and acupuncture+LY 294002 groups by lateral ventricular injection.Four hours and 24 h after modeling,the hippocampus tissues were sampled for observing pathological changes of CA 1 and CA 3 regions after H.E.staining under light microscope and for checking ultrastructural changes of the pyramidal cells under transmission electron microscope.Results In comparison with the normal control group,the numbers of pyramidal cells of hippocampal CA 3 region in the model group were decreased significantly 4 h and 24 h after epileptic seizure(P<0.01).While compared to the model group,the pyramidal cells of hippocampal CA 3 region in the acupuncture group were increased considerably in the number at both 4 h and 24 h after seizure(P<0.01).No significant differences were found between the LY 294002 and model groups,and between the acupuncture+ LY 294002 and model groups in the numbers of pyramidal cells at 4 h and 24 h after seizure(P>0.05).Findings of the light microscope and electron microscope showed that the injury severity of pyramidal cells of hippocampal CA 1 and CA 3 regions was moderate 4 h after epileptic seizure and even worse 24 h after seizure in the model group,LY 294002 group and acupuncture+LY 294002 group,but relatively lighter in the acupuncture group.These results suggested an elimination of the acupuncture effect after blocking the PI 3 K/Akt signaling pathway by lateral ventricular injection of LY 294002 in epilepsy rats.Conclusion Acupuncture intervention has a protective effect on pyramidal cells of hippocampal CA 1 and CA 3 regions in epilepsy rats,which is associated with the normal function of intracellular PI 3 K/Akt signaling pathway.关键词：Epilepsy;Epileptic seizure;Pyramidal cells;Hippocampus CA 1 and CA 3 regions;PI 3 K/Akt signaling pathway1617|395|6更新时间：2023-08-11
- 摘要：Objective To observe the effect of electroacupuncture(EA) of "Zhongwan"(CV 12),"Tianshu"(ST 20) and "Shangjuxu"(ST 37)(an acupoint prescription "Changbingfang" for treatment of intestinal disorders) on the expression of colonic nuclear factor κB p65(NF-κB p65) protein expression and serum interleukin-4(IL-4) content in rats,so as to explore its mechanism underlying improvement of ulcerative colitis(UC).Methods Thirty SD rats were randomly and equally divided into normal control,model and EA groups(10 rats/group).The UC model was made by enema with 8% acetic acid.EA stimulation(6 Hz/30 Hz) was delivered to "Zhongwan"(CV 12),"Tianshu"(ST 20) and "Shangjuxu"(ST 37) for 15 min separately,0 h,24 h and 48 h post-enema.The blood and colon tissues were taken for detection of serum IL-4 content with ELISA,and for assaying colonic NF-κB p65 protein expression with immunohistochemistry and Western blot,respectively.Results Compared with the normal control group,colonic NF-κB p65 protein expression level shown by immunohistochemistry and Western blot and serum IL-4 content were significantly higher in the model group(P<0.01,P<0.05).After EA stimulation,colonic NF-κB p65 protein expression levels shown by both immunohistochemistry and Western blot were down-regulated significantly(P<0.01,P<0.05) and serum IL-4 content was up-regulated further in comparison with the model group(P<0.01).Conclusion EA of acupoint recipe "Changbingfang" can down-regulate the proinflammatory NF-κB p65 protein expression and up-regulate serum anti-inflammatory cytokine IL-4 level in rats,which may contribute to its effect in improving ulcerative colitis.关键词：Ulcerative colitis;Electroacupuncture;Acupoint prescription "Changbingfang";Colonic nuclear factor κB p65 protein;Serum IL-41610|705|9更新时间：2023-08-11
- 摘要：Objective To observe the effect of electroacupuncture(EA) on the expression of suppressor of cytokine signaling 3(SOCS-3) and peroxisome proliferator-activated receptor(PPAR)-γ genes in the epididymis adipose tissue of obesity rats so as to explore its mechanism underlying weight reduction.Methods SD rats were randomized into normal control,obesity model,EA-5 mA and EA-1 mA groups(10 rats/group).EA stimulation(6 Hz/20 Hz,5 mA or 1 mA) was delivered to the bi-lateral "Zusanli"(ST 36) and "Sanyinjiao"(SP 6) for 15 min,once everyday for two weeks.The expression of SOCS-3 mRNA and PPAR-γ mRNA in the epididymis adipose tissue was detected by reverse transcriptase polymerase chain reaction.Results Compared with the normal group,the body weight and expression of SOCS-3 and PPAR-γ mRNA in the model group were up-re-gulated obviously(P<0.01).Compared with the model group,the body weight and expression of SOCS-3 and PPAR-γ mRNA were significantly decreased in the EA group,with the effects of EA-5 mA being better than those of EA-1 mA.Conclusion EA stimulation of ST 36-SP 6 can reduce body weight in rats with simple obesity,and the effect of higher intensity of EA is apparently better.Accordingly,EA intervention induces down-regulation of SOCS-3 and PPAR-γ mRNA expression in the epididymis adipose tissue.关键词：Simple obesity;Electroacupuncture;Adipose tissue;Suppressor of cytokine signaling;Peroxisome proliferator-activated receptor-γ1354|404|10更新时间：2023-08-11
- 摘要：Objective To observe the effect of electroacupuncture(EA) intervention on expression of phosphorylated mitogen activated protein kinase-P 38(p-P 38 MAPK) protein and Interleukin 1β(IL-1β)mRNA in the frontal lobe and hippocampus in Alzheimer's disease(AD) rats so as to explore its mechanisms underlying improvement of AD in clinic.Methods Thirty-two SD rats were equally and randomly divided into normal control(normal),sham-operation(sham),model and EA groups.AD model was established by microinjection of Aβ1-40(10 μg/μL,1 μL) into bilateral Meynert nucleus(AP:1.4 mm,L:3 mm,H:7 mm) and validated by water maze tests.Rats of the sham group were treated by microinjection of the same dose of normal saline into the bilateral Meynert Nucleus.EA(1 mA,2 Hz) was applied to bilateral "Baihui"(GV 20),"Taixi"(KI 3) and "Zusanli"(ST 36) for 15 min,once daily for 12 sessions.Expression levels of p-P 38 MAPK protein and IL-1β mRNA in the hippocampus and frontal lobe tissues were detected by Western blot and RT-PCR,respectively.Results In comparison with the normal group,the expression levels of p-P 38 MAPK protein and IL-1β mRNA in the hippocampus and frontal lobe tissues were upregulated significantly in the model group(P<0.01).After 12 sessions of EA intervention,the expression levels of both p-P 38 MAPK protein and IL-1β mRNA were down-regulated significantly(P<0.01,P<0.05) in spite of being still higher than those of the normal group.No significant differences were found between the normal and sham groups in the expression levels of both p-P 38 MAPK protein and IL-1β mRNA(P>0.05).Conclusion EA intervention can reduce the over expression of both p-P 38 MAPK protein and IL-1β mRNA in the hippocampus and frontal cortex in AD rats,suggesting an improvement of AD after EA intervention by restraining the inflammatory reaction.关键词：Alzheimer's disease;Electroacupuncture;p-P 38 MAPK protein;IL-1β mRNA;Hippocampus;Frontal cortex1547|800|8更新时间：2023-08-11
- 摘要：Objective To observe the effect of electroacupuncture(EA) stimulation of different acupoints or acupoint pairs on gastric motility so as to explore their modulation regularities under different conditions.Methods SD rats were randomly divided into normal control,starvation(food-deprivation for 24 h),atropine(antagonist for M-receptor),acetylcholine(Ach,agonist for M-receptor),propranolol(antagonist for β-receptor) and clenbuterol(agonist for β 2-receptor) and paired-acupoint groups(30 rats/group).The intragastric pressure was measured via a pressure transducer connected to a balloon inserted in the stomach cavity.EA(2 Hz /15 Hz,2 mA) was applied to the left "Tianshu"(ST 25),"Quchi"(LI 11) and "Shangjuxu"(ST 37) which were formed in pairs: ST 25-LI 11,ST 25-ST 37 and LI 11-ST 37 for 2 min following intravenous injection of atropine(0.1%,0.8 mL/kg,40 μL·min-1·kg-1),0.1% acetylcholine(20 μL·min-1·kg-1),0.2% clenbuterol(80 μL·min-1·kg-1) and 0.4% propranolol(1 mL/kg,40 μL·min-1·kg-1) under food-deprivation conditions.Results After intravenous injection of atropine and clenbuterol,the intragastric pressure were decreased significantly(P<0.05),while after administration of Ach and propranolol,the intragastric pressure increased markedly(P<0.05).Under normal and starvation conditions,and after intravenous administration of M-receptor antagonist(atropine) and agonist(Ach),β-receptor antagonist(propranolol) and agonist(clenbuterol),EA stimulation of ST 25 produced an apparently inhibitory effects on gastric motility(80.00%,86.67%,76.67%,86.67%,73.33% and 86.67%,respectively) and intragatric pressure(P<0.05) with the tendency being starvation >normal,acetylcholine >atropine and clenbuterol >propranolol.Whereas EA stimulation of LI 11 and ST 37 mainly produced an excitatory effect on gastric motility(60.00%,56.67%,93.33%,40.00%,53.33% and 50.00%,respectively for LI 11;66.67%,60.00%,80.00%,53.33%,46.67% and 73.33%,respectively for ST 37).Following EA stimulation of the paired-acupoint groups,ST 25-ST 37 induced a predominately inhibitory effect on gastric motility(50.00%) and intragastric pressure,while LI 11-ST 37 stimulation had a principally excitatory effect on gastric motility(53.33%),and ST 25-LI 11 showed no apparent effect(50.00%).Conclusion EA stimulation of ST 25 area at the abdomen produces a predominant inhibitory effect on gastric motility,while EA of LI 11 and ST 37 on the upper and lower limbs induces an excitatory effect on gastric movement,when applied in pairs,EA of ST 25-ST 37 suppresses the gastric activity,and LI 11-ST 37 promotes the gastric activity,suggesting a specificity of the effect of different acupoint stimulation.关键词：Intragastric pressure;Bi-directional regulation;Solo-acupoint;Paired-acupoint;Compatibility of acupoints1546|652|7更新时间：2023-08-11
- 摘要：Objective To observe the effect of electroacupuncture(EA) intervention on free radical metabolism in athletes during intensive endurance exercise,so as to reveal its mechanism underlying fatigue relief.Methods Thirty male college student volunteers were equally divided into control group,intensive endurance exercise group(exercise group for short) and EA group.Student volunteers in both exercise and EA groups were asked to conduct fixed quantitative load exercise(Harvard step test) for 30 min,once daily for 15 days.EA was applied to bilateral Xuehai(SP 10),Zusanli(ST 36),Taichong(LR 3),and San-yinjiao(SP 6) for 30 min,once daily for 15 days.Serum malondialdehyde(MDA) contents and superoxide dismutase(SOD) activity levels on the day before exercise,one day after exercise and 15 days after EA intervention were detected by using thioma-lonylurea colorimetric method and xanthine oxidase method,respectively.Results Compared with pre-exercise or the control group,serum MDA content and SOD activity after one day's intensive endurance exercise were increased significantly in both exercise and EA groups(P<0.05,P<0.01),and the ratios of SOD/MDA decreased considerably in the latter two groups(P<0.01).At the time-point of post-EA intervention,serum MDA level was significantly higher in the exercise group than in the control group(P<0.05),serum MDA content in the EA group was significantly lower than that in the exercise group(P<0.05),and serum SOD activity in the EA group was significantly higher than that in the exercise group(P<0.01).The ratio of SOD/MDA was increased obviously in the EA group than in the exercise group(P<0.01).Conclusion EA can decrease serum MDA content and increase SOD activity and SOD/MDA in athletes experiencing intensive endurance exercise,which may contri-bute to its effect in relieving athletic fatigue.关键词：Intensive endurance exercise;Electroacupuncture intervention;Athletic fatigue;Serum malondialdehyde;Serum superoxide dismutase1347|164|2更新时间：2023-08-11
- 摘要：Objective To observe the effect of Guasha(scraping) of Weizhong(BL 40) on the cutaneous blood perfusion of Qihaishu(BL 24) region of the Bladder Meridian on the back.Methods Ten healthy volunteer subjects were recuited in the present study.Weizhong(BL 40,at the politeal fossa) area was repeatedly scraped till regional flush using a cornu bubali scraping plate for 5 min after applying scraping oil to the regional skin.Then blood perfusion levels of the skin microcirculation around Weizhong(BL 40) and Qihaishu(BL 24) regions on the ipsilateral back were detected using a Laser Doppler flowmetry(PeriScan PIMⅡ).Results Following scraping Weizhong(BL 40) region,the cutaneous blood perfusion levels in the stimulated region were increased significantly at the time-points of 0,15,60 and 90 min after scraping(P<0.001,P<0.01),while those of Qihaishu(BL 24) area at the lumbar part also showed a remarkable increase 15,60 and 90 min after scraping compared with the basic value(P<0.05).A positive correlation was found between BL 40 and BL 24 areas in the cutaneous blood perfusion levels after scraping BL 40(P<0.05).Conclusion Scraping stimulation of Weizhong(BL 40) can improve the cutaneous microcirculation of the stimulated BL 40 and Qihaishu(BL 24) regions in healthy volunteers,suggesting a close connection between BL 40 and the back described in Chinese medicine.关键词：Scraping therapy;Cutaneous blood perfusion;Microcirculation;Weizhong(BL 40);Lumbar region1360|1100|7更新时间：2023-08-11
- 摘要：Objective To observe the effect of "equilibrium-acupuncture" intervention on lumbar pain in lumbar intervertebral disc prolapse patients.Methods A total of 287 patients with lumbar intervertebral disc prolapse syndrome were randomly assigned to equilibrium acupuncture group(n=143) and routine acupuncture group(n=144) using SAS(Statistical Analysis System) Software.Patients of the equilibrium acupuncture group were treated by acupuncture stimulation of bilateral "Yaotong" point(at the middle site of the forehead) and those of the routine acupuncture group treated by acupuncture stimulation of Ashi-points,Weizhong(BL 40),Jiaji(EX-B 2),Shenshu(BL 23),etc.The treatment was conducted once daily for 20 days,then,3 months' follow-up was given.Pain scores including pain rating index(PRI) and visual analogue scale(VAS) were given to the patients before and after the treatment using Chinese version of Short-Form of McGill Pain Questionnaire.Present pain intensity(PPI) was evaluated after the treatment.Results Before the treatment,no significant differences were found between the equilibrium acupuncture group and the routine acupuncture group in PRI and VAS scores(P>0.05).Following the treatment,the pain symptom was apparently improved in both groups,and the rates of pain improvement(including excellent,good and moderate improvement rates) of the equilibrium acupuncture group were significantly higher than those of the routine acupuncture group from the 1stto the 4th treatment sessions,in the 20th treatment session and the 2nd follow-up(P<0.05);and the PRI and VAS scores of the equilibrium acupuncture group were significantly lower than those of the routine acupuncture group after the 18thand 20thsessions of treatment and the 3 months' follow-up(P<0.05).The cases and percentages of patients without pain(PPI rating) were significantly more in the equilibrium acupuncture group than in the routine acupuncture group in the 18th and 20th treatment sessions and the 2nd follow-up(P<0.05).The "equilibrium-acupuncture" is relatively superior to routine acupuncture in the instant effect and long-term effect.Conclusion "Equilibrium-acupuncture" has a faster and stable long-term analgesic effect for lumbar intervertebral disc prolapse patients.关键词："Equilibrium-acupuncture";Prolapse of lumbar intervertebral disc;Acupuncture analgesia1824|1380|0更新时间：2023-08-11
- 摘要：Objective To observe the effect of electroacupuncture(EA) at different time-points after cervical carcinoma surgery on urinary bladder function of uroschesis patients so as to determine the optimum time of acupuncture intervention.Methods Sixty cervical cancer post-operation patients with catheter due to uroschesis were randomly and equally divided into late treatment group(acupuncture intervention was given from the over 15th day on after surgery) and early treatment group(acupuncture was given from the 7th day to the 14th day after surgery).Bilateral Shangliao(BL 31),Ciliao(BL 32),Zhongliao(BL 33),Xialiao(BL 34),Zhibian(BL 54),Yinlingquan(SP 9) and Sanyinjiao(SP 6) were punctured with filiform needles combined with electrical stimulation of bilateral BL 31 and BL 34 for 30 min,once daily for 10 sessions.The residual urine volume was measured before treatment and after 5 and 10 sessions of treatment separately.Results After 5 and 10 sessions of treatment,the average residual urine volumes of both late treatment and early treatment groups were decreased significantly(P<0.05),and the residual urine volume level of the early treatment group was markedly lower than that of the late treatment group(P<0.05).After 5 sessions of acupuncture treatment,of the two 30 cases in the late treatment and early treatment groups,8 and 17 had an automatic micturition,22 and 13 needed catheter retention,and following 10 sessions of treatment,22 and 27 had an automatic micturition,and 8 and 3 still needed catheter retention,respectively.Regarding the functional recovery state of the urinary bladder,of the two 30 cases in the late treatment and early treatment groups,6 and 14 were good,24 and 16 poor respectively following 5 sessions of treatment;15 and 22 were good,15 and 8 were poor respectively following 10 sessions of treatment.The therapeutic effects of the early treatment group were apparently superior to those of the late treatment group.The number of the treatment sessions for recovering the bladder function was obviously fewer in the early treatment group than in the late treatment group(P<0.05).Conclusion Early acupuncture intervention is significantly better than late treatment for reducing residual urine volume and promoting bladder function recovery for uroschesis patients undergoing cervical cancer operation.关键词：Cervical carcinoma operation;Acupuncture intervention;Uroschesis;Bladder function recovery1315|376|2更新时间：2023-08-11
- 摘要：Objective To detect the pain threshold of acupoints on the leg in healthy volunteers so as to analyze the sensory specificity of different acupoints.Methods A total of 66 healthy volunteers(34 male and 30 female) aged from 19 to 64 years were recruited in the present study.Pain thresholds of acupoints on the lower leg were detected by using an Electronic Von Frey Anesthesiometer after constructing an anthropometric diagram about the cutaneous division of the lower leg.Results 1) Among acupoints Shugu(BL 65),Jinggu(BL 64),Kunlun(BL 60),Chengshan(BL 57) of the Bladder Meridian from the heel to the popliteal fossa,and non-acupoint(1cun lateral to BL 60),no significant differences were found among these acupoint regions in the pain threshold(P>0.05),while that of the non-acupoint was significantly higher in comparison with these acupoint regions(P<0.05).2) At the Zusanli(ST 36) level,no significant differences were found among the Yanglingquan(GB 34),Zusanli(ST 36) and Yinlingquan(SP 9) regions in the pain threshold(P>0.05) and the pain threshold was obviously higher in the non-acupoint(1 cun lateral to ST 36) than in the GB 34,ST 36 and SP 9 regions(P<0.05).3)At the Xiajuxu(ST 39) level,no signi-ficant differences were found among the Xiajuxu(ST 39),Waiqiu(GB 36),Yangjiao(GB 35),Feiyang(BL 58) and Lougu(SP 7) regions in the pain threshold(P>0.05),but the non-acupoint(1 cun lateral to ST 39) showed a higher threshold than those of the above-mentioned 5 acupoints(P<0.05).4) Among the 5 Xing-spring acupoints Dadu(SP 2),Xingjian(LR 2),Neiting(ST 44) and Xiaxi(GB 43) distributing in the interdistal region,the pain threshold was lowest in the Neiting(ST 44) and highest in the Xiaxi(GB 43) regions(P<0.05).5) Among the acupoints Shuiquan(KI 5),Taixi(KI 3),Zhubin(KI 9) and Lougu(SP 7) on the lower leg,the pain threshold was lowest in the Zhubin(KI 9) and highest in the Lougu(SP 7) regions(P<0.05).Conclusion In healthy subjects,the pain threshold is generally higher in the non-acupoint region and also shows a sparse lower sensory thres-hold in some acupoints as Neiting(ST 44),Zhubin(KI 9),etc.The specificity of acupoints needs being studied further.关键词：Acupoint;Pain threshold;Meridian1264|301|1更新时间：2023-08-11
- 摘要：As a physical therapy,there is a certain relationship between the stimulating quantity and the efficacy of acu-moxibustion therapy.However,because of the thinking mode of traditional Chinese medicine in the ancient times,qualitative descriptions about acu-moxibustion stimulation in the classical literature are predominating.Mr.CHENG Dan-an,a famous master and educator of acupuncturology,conducted a series of exploration in both theory and clinical practice.In the present paper,the authors summarize Mr.Cheng's viewpoints about the quantification of acupuncture intervention from 1) the number of the selected acupoints in a session of treatment,2) gauges and materials of the filiform acupuncture needles,3) stimulating strength of the needling,including the duration of acupuncture needle retaining,depth of needling and intensity of the needling manipulation,4) frequency of the acupuncture intervention(interval between every two sessions of treatment).Regarding the moxibustion therapy,the stimulating quantity including the duration of the ignited moxa and the number of moxa cones applied at the acupoint area should be varied according to the patients' physical constitutions,ages and the state of the illness or clinical conditions.Mr.Cheng also put forward his opinions about the quantification standards of moxibustion intervention.关键词：CHENG Dan-an;Acupuncture and moxibustion;Stimulation quantity;Quantity-effect relationship1393|1048|12更新时间：2023-08-11
- 摘要：Exterior-interior relationship of meridians and zangfu organs is an important component of the theory of acupuncturology in Chinese medicine.According to the descriptions in classic works of Chinese medicine and findings of modern experimental researches,in the present paper,the authors analyzed the close association between the "Heart" and "Small Intestine",exterior-interior correlation between the Heart Meridian and Small Intestine Meridian,and between the "Heart" and body surface(acupoints),limbs,five sensory organs,etc.In addition,the authors also summarized the underlying mechanisms of the above-mentioned exterior-interior relationship of the "Heart" and put forward some proposals for the future researches.关键词：Heart;Exterior-interior relationship;Correlation between meridians and internal organs;Classic descriptions;Mechanism1075|754|2更新时间：2023-08-11
- 摘要：A large number of clinical trials and animal experiments have been carried out to focus on neurochemical mec-hanisms of acupuncture analgesia including postoperation pain relief,which may provide guidance for developing a novel clinical approach for postoperative analgesia.In the present paper,the authors review new progresses of researches on acupuncture analgesia for postoperative pain and side effects in the past few years from thyroidectomy,chest surgery,abdominal surgery,five sense organs(ear,nose,eye and throat) surgery,and others.Regarding the mechanism of acupuncture,central neurotransmitters(including the endop endorphin,5-HT,gamma-aminobutyric acid,etc.),immune cytokines,cytokines from the spinal glia cells are complicated in the process of acupuncture analgesia.A lot of findings of researches demonstrated that acupuncture therapy is effective in reducing postoperative pain and adverse reactions as nausea,vomiting,etc.As a common technique widely used in the field of clinical medicine,the underlying mechanisms of acupuncture therapy for relieving post-surgery pain and side-effects should be studied profoundly in the future.关键词：Acupuncture analgesia;Surgical operation;Postoperative pain;Adverse reaction;Mechanism1167|1277|3更新时间：2023-08-11
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