最新刊期
卷 38 ， 期 5 ， 2013
- 摘要：Objective To observe the changes of gastric motility and levels of substance P(SP)and motilin(MTL)in the gastric antrum and Nucleus Raphe Magnus(NRM)after manual acupuncture stimulation of"Zusanli"(ST 36)in gastric hyperactivity and hypoactivity rats,so as to analyze the role of NRM in acupuncture mediated adjustment of gastric motility.Methods Fifty SD rats were randomly and equally divided into control,gastric hyperactivity(G-Hypera)model,gastric hypoactivity(G-Hypoa)model,acupuncture+ G-Hypera and acupuncture+ G-Hypoa groups(10rats/group).G-Hypera model was established by intravenous(tail vein)injection of Maxolon(0.5mL/200g)and G-Hypoa model established by intravenous injection of Atropin(0.5mL/200g),respectively.After insertion of acupuncture needles into bilateral"Zusanli"(ST 36),the needles were repeatedly manipulated at a frequency of about 2Hz for 5min.The intragastric pressure was recorded and analyzed using aphysiological signal analysis system.The SP and MTL contents of gastric antrum were measured by ELISA,and SP and MTL immunoactivity of NRM was determined by immunohistochemistry.Results In gastric hyperactivity rats,compared with the control group,the intragastric pressure(not systolic frequency),SP and MTL contents in the gastric antrum and MTL immunoactivity of NRM were significantly increased(P<0.05,P<0.01),while SP immunoactivity of NRM was apparently decreased in the G-Hypera model group(P<0.01).After acupuncture stimulation,the intragastric pressure,gastric SP and MTL contents,and MTL immunoactivity of NRM were all significantly down-regulated(P<0.05,P<0.01),and SP immunoactivity of NRM was markedly up-regulated(P<0.01)in comparison with the model group.In gastric hypoactivity rats,compared with the control group,the intragastric pressure and gastric systolic frequency,gastric SP and MTL contents,and MTL immunoactivity of NRM were significantly decreased(P<0.05,P<0.01),while SP immunoactivity of NRM was remarkably up-regulated in the G-Hypoa model group(P<0.01).After acupuncture stimulation,the above-mentioned 6indexes were reversed significantly(P<0.05,P<0.01)in comparison with those of the model group.Conclusion Acupuncture stimulation of"Zusanli"(ST 36)has an obvious bi-directional adjustment effect on gastric motility,which is closely associated with its functions in regulating gastric SP and MTL level and the expression of MTL and SP in the NRM of brainstem.关键词：Acupuncture intervention;Gastric motility;Gastric hyperactivity;Gastric hypoactivity;Substance P;Motilin;Nucleus Raphe Magnus1333|828|13更新时间：2023-08-11
- 摘要：Objective To observe the effect of drug-paste separated moxibustion of"Mingmen"(GV 4)on the levels of serum estrogen(E2)and progesterone(P)and their endometrial receptor mRNA expression in rats with primary dysmenorrhea in order to investigate its mechanism underlying improvement of primary dysmenorrhea.Methods A total of 100female SD rats were randomized into control,model,medication,acupuncture and moxibustion groups,with 20rats in each group.Primary dysmenorrhea model was established by subcutaneous injection of Benzestrofol for 10days and intraperitoneal injection of Oxytocin for1d.Rats of the medication group were fed with extractum leonuri inspissatum(8g/100g)and those of the moxibustion group treated with drug-paste separated moxibustion at"Mingmen"(GV 4).For rats of the acupuncture group,a filiform needle was inserted into GV 4,manipulated for a while and retained for 30min.The treatment of the latter 3groups was conducted once daily for 7days.The rat's body-writhing latency and times during 30min were recorded.The contents of serum E2and P were detected by ELISA,and the expression of estrogen receptor(ER)mRNA and progesterone receptor(PR)mRNA in the endometrium was determined by quantitative real-time(RT)-PCR.Results ①The body-writhing latency was shorter and the writhing times were more in the model group than in the control group(P<0.01).Compared with the model group,the body-writhing latency was significantly increased and the writhing times were obviously decreased in the medication,acupuncture and moxibustion groups(P<0.01).There were no significant differences among the medication,acupuncture and moxibustion groups in the body-writhing latency(P>0.05),but the body-writhing numbers of the acupuncture and moxibustion groups were markedly lower than that of the medication group(P<0.01).②Compared with the control group,serum E2content and endometrial ER mRNA expression level were significantly increased,and serum P content and endometrial PR mRNA level evidently decreased in the model group(P<0.01,P<0.05).In comparison with the model group,serum E2contents and endometrial ER mRNA expression levels were considerably down-regulated,and serum P contents and endometrial PR mRNA expression levels markedly up-regulated in the medication,acupuncture and moxibustion groups(P<0.01,P<0.05).The effects of the moxibustion group were significantly superior to those of the acupuncture and medication groups,and those of the acupuncture group were also significantly superior to those of the medication group in lowering E2and endometrial ER mRNA levels,and raising serum P and endometrial PR mRNA expression levels(P<0.01,P<0.05).Conclusion Drug-paste separated moxibustion of GV 4is effective in relieving pain in primary dysmenorrheal rats,which is probably associated with its effects in down-regulating serum E2content and endometrial ER mRNA expression,and up-regulating serum P and endometrial PR mRNA expression levels.1587|680|4更新时间：2023-08-11
- 摘要：Objective To observe the effect of"Sanjiao Acupuncture Therapy"on hippocampal selective neuron loss and astrocytosis in senile accelerated mice(SAM)so as to reveal its mechanism underlying improvement of Alzheimer's disease(AD).Methods A total of 18seven-month old male SAM prone 8(SAMP 8)were selected and randomly allocated into model group,acupuncture group,and non-acupoint group.Moreover,6age-and sex-matched SAM resistant 1(SAMR 1)were enrolled as the homology normal control group.For mice of the acupuncture group,"Sanjiao Acupuncture Therapy"[manual acupuncture stimulation of"Danzhong"(CV 17),"Zhongwan"(CV 12),"Qihai"(CV 6),"Zusanli"(ST 36)and"Xuehai"(SP 10)]was given,and for rats of the non-acupoint group,manual acupuncture stimulation was applied to bilateral costal region(non-acupoints,below the costal region and 10and 15mm superior to the iliac crest).The treatment was conducted once daily for 14days.At the end of each experiment,the mouse's hippocampus tissue was taken out after routine perfusion and fixing for paraffin sections which were stained by toluidine blue technique for observing changes of neurons and by immunohistochemistry for analyzing glial fibrillary acidic protein(GFAP)immunoactivity of astrocytes.Results Compared with the control group,a marked neuron loss was found in the model,acupuncture and non-acupoint groups(P<0.01).The numbers of neurons of hippocampal CA 1and CA 3regions in the acupuncture group were significantly more than those in the model group(P<0.05).Compared with the control group,the expression level of hippocampal GFAP was markedly increased in the model group(P<0.01).In comparison with the control group,the average expression area,optical density values and the number of GFAP-labeled astocytes were significantly upregulated in the model group(P<0.01).While in comparison with the model group,these 3indexes were apparently downregulated in the acupuncture group(P<0.01)but not in the non-acupoint group except the average expression area,suggesting a reduction of hippocampal astrocyte activity after acupuncture intervention.A negative correlation was found between the expression level of GFAP and the number of astrocytes.Conclusion "Sanjiao Acupuncture Therapy"can lower or delay neuron loss,suppress astrocytosis,and regulate the relationship between neuron and astrocyte,which may contribute to its function in relieving AD.关键词：AD(Alzheimer's disease);Acupuncture therapy;Neuron loss;Glial fibrillary acidic protein expression;Astrocyte;Senile accelerated mouse(SAM1696|406|8更新时间：2023-08-11
- 摘要：Objective To observe the effect of electroacupuncture(EA)stimulation of"Zusanli"(ST 36)and"Zhongwan"(CV 12)on blood-lipid,high-sensitivity C-reactive protein(HS-CRP)and adiponectin(ADPN)levels in hyperlipidemia rats,so as to study its mechanisms underlying improvement of hyperlipidemia.Methods Thirty-two male Wistar rats were randomly divided into control group,model group,manual acupuncture group and EA group(n=8in each group).Hyperlipedemia model was established by feeding the rats with high fat diet for 40days.Manual acupuncture and EA stimulation were separately applied to unilateral"Zusanli"(ST 36)and"Zhongwan"(CV 12),once daily for 4weeks.Serum triglyceride(TG),total cholesterol(TC),high density lipoprotein cholesterol(HDL-C),low density lipoprotein cholesterol(LDL-C)levels were determined by chromatometry,and serum HS-CRP and ADPN contents detected by immunity turbidimetric method and euzymelinked immunosorbent assay,respectively.Results Compared with the control group,serum TC,TG,LDL-C and HS-CRP levels were significantly upregulated in the model group(P<0.05,P<0.01),while serum HDL-C and ADPN levels remarkably reduced after modeling(P<0.05,P<0.01).In comparison with the model group,serum TC,TG,LDL-C and HS-CRP contents were considerably decreased in both manual acupuncture and EA groups(P<0.05,P<0.01),and serum HDL-C and ADPN contents were evidently upregulated in the manual acupuncture and EA groups(P<0.05,P<0.01).The effect of EA in decreasing serum TC,TG,LDL-C and HS-CRP,and increasing serum ADPN was superior to that of manual acupuncture(P<0.05).Conclusion EA intervention has a remarkably positive effect on hyperlipidemia by reducing serum TC,TG,LDL-C and HS-CRP contents and upregulating serum HDL-C and ADPN levels in hyperlipidemic rats.关键词：Electroacupuncture;Hyperlipidemia;High-sensitivity C-reactive protein;Adiponectin;Blood-lipid;Liver adipose degeneration1464|209|4更新时间：2023-08-11
- 摘要：Objective To observe changes of anesthesia analepsia time and hypothalamic and hippocampal corticotropin-releasing factor(CRF)protein expression after electroacupuncture(EA)intervention in acute traumatic rats,in order to explore its mechanism underlying relief of post-operative stress.Methods Twenty male Sprague-Dawley rats were randomly divided into normal control group,model group,sham EA group and EA group(5rats/group).Acute traumatic model was established by left lobectomy.For rats of the sham EA group,two filiform needles were inserted into the right"Zusanli"(ST 36)and"Sanyinjiao"(SP 6)respectively,without needle-twirling and without electrical stimulation.For rats of the EA group,the right ST36and SP 6were electrically stimulated at 2Hz/100Hz and 2mA for 30minutes after needle insertion.Anesthesia analepsia time was recorded and righting reflex was tested for the acute traumatized rats.The expression of CRF protein in the hypothalamus and hippocampus was analyzed with Western blot.Results The anesthesia analepsia time and righting reflex recovery time were significantly shorter in the EA group than in the model group and sham EA group(P<0.01).There was a close correlation between the anesthesia analepsia time and righting reflex recovery time(P<0.05).In comparison with the normal group,the expression level of hippocampal CRF protein was significantly decreased whereas that of hypothalamic CRF protein evidently increased in the model group(P<0.05).Compared with the model group,hippocampal CRF protein expression was considerably upregulated and hypothalamic CRF protein remarkably down-regulated in the EA group(P<0.05).A markedly negative correlation was found between hypothalamic CRF and hippocampal CRF protein expression,and between hippocampal CRF expression and the stimulating mode(P<0.001),and a positive correlation was found between hypothalamic CRF expression and righting reflex,and between hippocampal CRF expression and EA intervention(P<0.01).Conclusion EA intervention can shorten anesthesia analepsia time and righting reflex recovery time in liver-traumatized rats,which is closely associated with its effects in upregulating hippocampal CRF protein expression and down-regulating hypothalamic CRF expression.It suggests that CRF mediated hippocampus-hypothalamus-pituitary-axis is involved in EA induced reduction of post-surgical stress.关键词：Acute traumatic stress;Electroacupuncture intervention;Corticotropin-releasing factor stress system;Hypothalamus;Hippocampus;Anesthesia analepsia time;Righting reflex;Correlation analysis1464|276|3更新时间：2023-08-11
- 摘要：Objective To observe the distribution of neurons and their axonal projection associated with"Yongquan"(KI 1)area by neural tracing technique with cholera toxin subunit B(CTB).Methods A total of 5μL of 1% CTB solution was injected into the front central part of hind foot plantar(corresponding to the KI 1region in the human body)using a Hamilton microsyringe.After 3survival days,the rats were deeply anesthetized and transcardically perfused for collecting the dorsal root ganglia(DRGs),spinal cord and brain tissues.Following fixing in 4%paraforldehyde containing phosphate buffer solution(PBS)and incubation in PBS containing 25% glucose solution,the aforementioned tissues were sectioned to be stained with immunofluorescence or immunohistochemistry for revealing the labeled sensory neurons and their tansganglionic projection and motor neurons.Results All the labeled neurons(sensory and motor neurons)and transganglionic axonal projection appeared ipsilaterally to the injection side.The labeled sensory neurons were located in the DRGs of lumbar 3-5segments(L 3-L 5)with a higher concentration at L 4,while motor neurons distributed in the dorsolateral portion of spinal ventral horn from L 3to L 6with a higher concentration at L 5.In addition,transganglionic axonal projections were found to situate in the medial part of laminaeⅢ-Ⅳfrom L 3to L 5,as far as in the gracile nucleus.Conclusion Acupoint KI 1area is innervated by sensory neurons in L 3-L 5DRGs and motor neurons from the dorsolateral ventral horns of L 3-L 6.The axonal projection of the primary sensory neurons distributes in the medial part of laminaeⅢ-Ⅳ of L 3-L 5and gracile nucleus,respectively.关键词：Yongquan(KI 1);Innervation;Neural tracing;Cholera toxin subunit B(CTB);Sensory neurons;Motor neurons1611|438|6更新时间：2023-08-11
- 摘要：Objective To observe the changes of N-methyl-D-aspartic acid(NMDA)receptor expression of spinal cord after electroacupuncture(EA)intervention in rats with chronic constrictive injury(CCI)of the sciatic nerve so as to reveal the mechanism underlying improvement of neuropathic pain.Methods Sixty male SD rats were randomly divided into sham operation(sham)group,CCI model group and EA group(n=20).CCI model was established by ligature of the right sciatic nerve with apiece of surgical chromic suture.For rats of the sham group,the right sciatic nerve was just isolated without ligature.The rats of the EA group were given with EA stimulation of"Weizhong"(BL 40)and"Huantiao"(GB 30)on the injured side at a frequency of 2Hz,electric current of 1-3mA for 30min(increasing 1mA every 10min).The treatment was conducted once a day from the11th day to the 20th day after modeling.NMDA receptor 2Bsubunit(NR 2B)protein and mRNA expression levels in the spinal cord were determined by immunohistochemistry,Western blot and reverse transcription(RT)-polymerase chain reaction(PCR),respectively,and spinal NMDA receptor subunit 1(NR 1)protein and mRNA expression levels were measured by Western blot and RT-PCR,respectively.Results In comparison with the sham group,NR 1protein and mRNA expression levels of the model group in the spinal cord were considerably upregulated after CCI(P<0.01,P<0.05).In comparison with the model group NR 1protein and mRNA expression levels of the EA group in the spinal cord were evidently down-regulated(P<0.05).No significant changes of NR 2Bprotein and mRNA expression after CCI and EA stimulation were found after immunohistochemistry,Western blot and RT-PCR measurements(P>0.05).Conclusion EA intervention is effective in alleviating neuropathic pain in CCI rats,which may be closely related to its effects in lowering functional activity of NR 1protein and mRNA in the spinal cord.1260|269|6更新时间：2023-08-11
- 摘要：To observe the effects of electroacupuncture(EA)stimulation of"Zusanli"(ST 36)and"Sanyinjiao"(SP 6)at different time-points of a day on the expression of c-fos and neuronal nitric oxide synthase(nNOS)in the medial prefrontal cortex(mPFC)in rats with ketamine addiction.Methods A total of 56SD rats were randomized into control group,saline group,model group and EA group.The EA group was further divided into Zi-shi(23:00),Mao-shi(05:00),Wu-shi(11:00)and You-shi(17:00)subgroups(n=8in each group or subgroup).Ketamine addiction model was established by intraperitoneal administration of ketamine(100mg/kg),once a day for 7days.EA(2Hz,3V)was applied to unilateral"Zusanli"(ST 36)and"Sanyinjiao"(SP 6)acupoints for 30min,once daily for 7days.The expression of c-fos and nNOS in the mPFC was detected by immunohistochemistry.Results Following EA intervention for 7days,the animals' daily life activities including body stretching,standing,jumping,circling,falling on the back and fur-licking in the EA group(Wu-shi and You-shi subgroups)were close to those of the normal control and saline groups,being much better than the model group.Compared with the normal control group and saline group,the expression levels of c-fos and nNOS in the mPFC in the model group were significantly upregulated(P<0.05).Compared with the model group,the expression levels of both c-fos and nNOS were considerably down-regulated in the Wu-shi(11:00)and You-shi(17:00)subgroups(P<0.05),rather than in the Zi-shi(23:00)and Mao-shi(05:00)subgroups(P>0.05).Conclusion EA of ST 36and SP 6at 11:00and 17:00can decrease the expression of c-fos and nNOS in the mPFC in ketamine addiction rats,which may contribute to its effects in improving the rats' behavior activity.关键词：Ketamine addiction;Electroacupuncture;Chronomedicine;Medial prefrontal cortex;c-fos;Neuronal nitric oxide synthase;Immunohistochemistry2491|269|1更新时间：2023-08-11
- 摘要：Objective To compare the cumulative analgesic effect of electroacupuncture(EA)stimulation of Sanyinjiao(SP 6),Xuanzhong(GB 39)and non-acupoint for primary dysmenorrhea patients.Methods A total of 200patients with primary dysmenorrhea were randomly assigned to Sanyinjiao(SP 6,a dysmenorrheal-relieving related acupoint)group,Xuanzhong(GB 39,an unrelated acupoint)group,non-acupoint group and control group,with 50cases in each group.The participants were administered with EA(2Hz/100Hz,0.5-1.6mA)at SP 6,GB 39and non-acupoint for 30min,once daily for 3consecutive days.The intensity of the pain was ranked from 0(no pain)to 100(intolerable)using visual analogue scale(VAS)and RSS(Cox retrospective symptom scale)severity rating scores(RSS-COX 2)before and after three interventions.Results In comparison with the control group,VAS and RSS-COX 2scores were significantly lower in the SP 36,GB 39and non-acupoint groups(P<0.001,P<0.05),suggesting an alleviation of the pain severity after EA treatment.No significant differences were found among the three treatment groups in both VAS and RSS-COX 2scores(P>0.05).Conclusion EA stimulation of SP 6,GB 39and non-acupoint has a good cumulative analgesic effect in patients with primary dysmenorrhea.关键词：Primary dysmenorrhea;Cumulative analgesic effect;Sanyinjiao(SP 6);Xuanzhong(GB 39);Nonacupoint;Multicenter randomized controlled clinical trial1410|1112|5更新时间：2023-08-11
- 摘要：Objective To observe the clinical effect and safety of Sulfasalazine(SASP)combined with ZHUANG medicine mediated thread moxibustion(ZMMTM)for patients with mild and moderate ulcerative colitis(UC).Methods A total of 46UC patients were randomly and equally divided into moxibustion group(SASP combined with ZMMTM)and SASP medication group.Patients of both groups were treated by oral administration of SASP(1g,tid)for six weeks.For patients of the moxibustion group,ZMMTM was applied to points Tianshu(ST 25),Qihai(CV 6),Guanyuan(CV 4),and Dachangshu(BL 25),once a day,for 20times.The therapeutic effect was assessed according to Schroeder and colleagues' method(1987),scores of Baron's endoscope scale(0-9scoring standards,1964),0-3scoring standards of activity indexes(including 4items of diarrhea,hemorrhage,mucosal appearance and doctors' evaluation),respectively.Results Of the two 32UC patients in the medication and moxibustion groups,6and 9had a complete remission in their symptoms,6and 7experienced a remarkable improvement,5and 6were effective,and 6and 1was invalid,with the effective rates being 73.91% and 95.65%,respectively.Following the treatment,both endoscopic score and activity index in the moxibustion group were significantly lower than those of the medication group(P<0.05).Conclusion ZMMTM combined with medication is significantly superior to simple medication in relieving clinical symptoms of mild and moderate UC patients.关键词：Ulcerative colitis;ZHUANG medicine mediated thread moxibustion;Sulfasalazine;Clinical effect;Mucosal lesion;Activity index1491|227|3更新时间：2023-08-11
- 摘要：Objective To observe the clinical effect of electroacupuncture(EA)combined with sitting training for cerebral palsy(CP)children with parafunctional sitting position.Methods A total of 120parafunctional sitting CP child patients were randomly and equally divided into sitting training(control)group and EA plus sitting training(EA)group.The sitting training included assistant-sitting,legs-crossing-sitting,sitting with one-leg extending,long-term sitting,balancing-sitting,chair-climbing,and pron and hand-supporting,twice daily.EA(4Hz,a tolerable strength)was applied to Mingmen(GV 4),Jizhong(GV 6),Shenshu(BL 23),and Pishu(BL 20)for 30min,once daily.Both sitting training and EA treatment were conducted 5times a week and continuously for a month.Twenty-items of sitting functions(0-3point scaling)of Gross Motor Function Measure(GMFM)were used to evaluate the infantile patients' motor function and Nimodipine-method was employed to assess the curative effect.Results The sitting function scores were significantly increased in both control and EA groups compared with pre-treatment in the same one group(P<0.01),and were apparently higher in the EA group than in the control group(P<0.05),suggesting a better therapeutic effect of EA plus sitting training.EA plus sitting training intervention was better for the spastic and hypotonic patterns of CP patients than the other patterns in the therapeutic effect(P<0.01).Of the two 60cases of CP children in the control and EA groups,20(33.33%)and 22(36.67%)experienced marked improvement,24(40.00%)and 30(50.00%)were effective,and 16(26.67%)and 8(13.33%)failed,with the effective rates being 73.33% and 86.67% respectively.Conclusion Acupuncture intervention combined with sitting training is better than sitting training intervention alone in improving cerebral palsy children with parafunctional sitting position,especially for the spastic and hypotonic CP patients.关键词：Cerebral palsy;Acupuncture therapy;Sitting training;Comprehensive treatment1292|315|4更新时间：2023-08-11
- 摘要：Objective To observe the curative effect of acupuncture intervention combined with hyperbaric oxygen chamber treatment for delayed encephalopathy in 32carbon monoxide(CO)poisoning patients.Methods A total of 62CO poisoning encephalopathy patients were randomized into control group(n=30)and acupuncture group(n=32).Patients of the two groups were all treated with medicines(energy mixture solution,hormones,brain cell activators,calcium ion blockers,anti-inflammatory agents,etc.)and hyperbaric oxygen treatment(oxygen-inhaling for 90min/time).Moreover,patients of the acupuncture group received acupuncture stimulation of bilateral Taixi(KI 3),Xuanzhong(GB 39),Hegu(LI 4),Taichong(LR 3),and Fengchi(GB 20).All the treatments were conducted once daily for 30days.The therapeutic effect of the treatments for neurological function was assessed by NIH Stroke Scale(NIHSS,34points in total;including 15items as consciousness,horizontal eye movement,visual power,visual field,facial muscular motion,limb movement,coordination movement,sensory and language levels,etc.).Results After the treatment,of the 30and 32cases in the control and acupuncture groups,1and 4were cured,3and 8experienced marked improvement,4and 11were improved,and 22and 9invalid,with the effective rates being 26.1%and 72.3%,respectively.The therapeutic effect of the acupuncture group was significantly superior to that of the control group(P<0.05).The average NIHSS score was 5.01±0.72in the acupuncture group,being significantly lower than that(8.30±0.45)in the control group(P<0.05).Conclusion Acupuncture treatment can effectively strengthen the efficacy of hyperbaric oxygen therapy in the treatment of delayed encephalopathy caused by carbon monoxide poisoning.关键词：Carbon monoxide poisoning;Delayed encephalopathy;Acupuncture intervention;Hyperbaric oxygen therapy1665|202|3更新时间：2023-08-11
- 摘要：Objective To observe the therapeutic effect of cervical paravertebral block plus acupuncture treatment for cervicogenic headache.Methods Sixty cases of cervicogenic headache were randomly and equally divided into cervical paravertebral block(control)group and acupuncture plus cervical paravertebral block(acupuncture)group.Paravertebral block was performed by injection of 5mL of 0.3%lidocaine solution containing triamcinolone(10mg)into the 2nd cervical paravertebral tissue from the cross point between the posterior border of the sternomastoid muscle and the angle of jaw,once every week for three weeks.Manual acupuncture stimulation was applied to Baihui(GV 20),unilateral Fengchi(GB 20)and Jiaosun(SJ 20),once daily for 3weeks.The patients' headache severity was assessed by visual analogue scale(VAS)and their cervical vertebral activity assessed by range of motion(ROM)before and after the treatment.Results Compared with pre-treatment in the same one group,the scores of both VAS and ROM at time points of one,two and three weeks after the treatment were significantly decreased in the control and acupuncture groups(P<0.05),suggesting a marked improvement of both headache and cervical motion after the treatment.Comparison between the two groups showed that the VAS and ROM scores of the acupuncture group were evidently lower than those of the control group at each time point after the treatment(P<0.05),displaying a better therapeutic effect of acupuncture plus paravertebral block for cervicogenic headache.Conclusion Acupuncture combined with cervical paravertebral block is effective in relieving cervicogenic headache and improving cervical vertebral activity in cervicogenic headache patients,and can strengthen the therapeutic effect of simple paravertebral block.关键词：Cervicogenic headache;Acupuncture intervention;Cervical paravertebral block;Clinical therapeutic effect1143|243|1更新时间：2023-08-11
- 摘要：Objective To observe the features of acupuncture needle twirling manipulations in order to promote the development of objective and quantitative performance standards of acupuncture manipulation.Methods Twelve expert acupuncturists and 12novices were enrolled in this study.Everyone of them was instructed to perform 10trials of the uniform reinforcing and reducing technique of acupuncture on an artificial skin-pad that was mounted to a six-axis force transducer and each subject had his or her dominant hand index finger affixed with an infrared light emitting diode for acquiring parameters of acupuncture needle manipulation.The force transducer was used to measure the force the participant applied as they held an acupuncture needle to stimulate the skin-pad,and at the mean time,an optoelectric camera was employed to measure the position of the diode.Results In comparison with the expert acupuncturist group,the straggling coefficient of needle-twirling frequency was significantly bigger in the novice group(P<0.01),suggesting a higher consistency in the trial-by-trial needle-twirling operation of the expert acupuncturists.Comparison of the needle-twirling force showed that the force values of the Z-axis in both expert group and novice group were considerably higher than those of the X-axis and Y-axis in the same one group(P<0.01).The time of pre-needle-twirling of the novice group was markedly longer than that of the expert group(P<0.01),suggesting a skilled operation technique of the expert acupuncturists.No significant differences were found between the expert acupuncturist group and novice group in the needletwirling amplitude,frequency,force and total operation time(P>0.05).Conclusion Movement frequency consistency and temporal efficiency are the action features of expert acupuncturists in performing the uniform reducing-reinforcing twirling skill,which differentiates the performances of experts from novices.The assessment and training of this acupuncture skill should focus on these kinematic features.关键词：Acupuncture skill;Kinematics;Kinetics;Quantitative analysis1080|331|4更新时间：2023-08-11
- 摘要：Objective To analyze the application rules of the red-hot needle therapy to the treatment of neurological dysfunction related diseases in the ancient and modern clinical practice by data mining.Methods Modern literature data about the red-hot needle therapy in medical journals and partial medical books were collected to establish a"red-hot needling literature network database",followed by manually selecting its applicable illness spectrum of neurological dysfunction.Then,the application rules of the red-hot needling for neurological dysfunction related diseases,including selection of acupuncture needle types,acupoints,operation methods,etc.were analyzed.Results A total of 17categories of neurological dysfunction related diseases treated by red-hot needle therapy were collected from medical journals,ten categories of diseases collected from medical cases,and five categories of diseases collected from medical books.The most frequently seen diseases were herpes zoster/residual neuralgia of herpes zoster,facial paralysis,facial neuritis(prosopodynia),and stroke/stroke sequelae,etc.During acupuncture treatment,doctors(acupuncturists)usually selected Ashi points,performed spot pricking or quick insertion and withdrawal of the red-hot needle,or adopted additional surrounded needling around the focus of infection according to syndrome differentiation in some cases.Conclusion Red-hot needle therapy has a good curative efficacy in relieving symptoms of neurological dysfunction related diseases,being worthy of promotion in clinical practice.关键词：Red-hot needle therapy;Neurological dysfunction diseases;Data mining;Literature research1253|916|6更新时间：2023-08-11
- 摘要：Functional status is an important factor affecting clinical therapeutic effect of acupuncture therapy.Authors of the present article make an analysis on the related descriptions of ancient classical books about the patient's body constitution,age,duration of disease,type of disease or clinical conditions,psychological state,etc.which determine the functional state of patients.Moreover,the authors also make some comments on the results of modern clinical trials and experimental studies.However,till now,the results of many related modern studies were lower in reliability due to unreliable methodology.Fewer clinical trials involve the patient's psychological state,and constitution from the viewpoint of Chinese medicine.Correspondingly,the related experimental studies are fewer.The authors suggest that in the coming days clinical trials should be greatly improved in quality and the mutual interference among the influential factors should be excluded.At the same time,experimental studies on the related biochemical mechanisms should be strengthened.关键词：Acupuncture therapy;Functional status;Influential factors;Clinical trials;Experimental studies1484|459|3更新时间：2023-08-11
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