最新刊期
卷 43 ， 期 1 ， 2018
- 摘要：Objective To observe the effect of electroacupuncture(EA)and moxibustion(Moxi)pretreatment on myocardial pathological and structural changes and expression of autophagy related protein LC 3 Ⅰ/Ⅱ and Beclin 1 in rats with myocardial ischemia-reperfusion injury(MI/RI),so as to explore their mechanisms underlying improving MI/RI.Methods Forty SD rats were randomly divided into sham operation,model,ischemic preconditioning(IP),EA and Moxi groups(n=8 in each group).EA(10 Hz/50 Hz,1 mA)or Moxi(ignited moxa stick)was respectively applied to bilateral"Neiguan"(PC 6)for 20 min,once daily for 7 days.The MI/RI model was established by occlusion of the anterior descending branch of the left coronary artery for 40 min,followed by reperfusion for 60 min.The left ventricular(LV)tissue samples were collected and analyzed for pathological(H.E.staining)and ultrastructural changes,for myocardial apoptosis(apoptotic index= number of apoptotic cells/total number of cardiomyocytes×100%)with terminal deoxynucleotidyl transferase dUTP nick end labeling(TUNEL)method,and for the expression of LC 3 and Beclin 1 in myocardial cells with Western blot.Results Following MI/RI,H.E.staining revealed a disorder of arrangement of cardiomyocytes with vague border,inflammatory cell infiltration,intracellular swelling with bleeding,necrosis and dissolution of partial striated muscles of the left ventricle under light microscope,and dual staining of Uranyl acetate and leadnitrate showed atrophy,arrangement disorder,dissolution,necrosis,and interstitial edema of partial myocardial fibers,mitochondrial structural disorder,vacolation,and large body of autophagosomes with bilayers,etc.in ultrastructure,which was relatively lighter in both EA and Moxi groups.The apoptosis index,expression levels of myocardial LC 3Ⅱ and Beclin 1 and the ratio of LC 3 Ⅱ/LC 3 Ⅰ were significantly higher in the model group than those in the sham operation group(P<0.01),but the expression level of LC 3 Ⅰ was considerably down-regulated in the model group relevant to the sham operation group(P<0.01).Following the intervention and MI preconditioning,the increased apoptosis index and expression levels of LC 3Ⅱ and Beclin 1 proteins and the ratio of LC 3Ⅱ/LC 3 Ⅰ were obviously down-regulated in the IP,EA and Moxi groups relevant to the model group(P<0.01),and the decreased expression of LC 3 Ⅰ protein was up-regulated obviously in the 3 treatment groups(P<0.05,P<0.01).The effects of EA were significantly superior to those of IP and Moxi groups in down-regulating apoptosis index and expression of LC 3Ⅱand Beclin 1 and the ratio of LC 3Ⅱ/LC 3Ⅰand in up-regulating expression of LC 3Ⅰ(P<0.05,P<0.01).Conclusion Both EA and Moxi preconditioning of PC 6 have a protective effect on ischemic myocardium in MI/RI rats,which is probably related to their effects in regulating expression of myocardial autophagy proteins as LC 3 Ⅰ/Ⅱ and Beclin 1.关键词：Electroacupuncture pretreatment;Moxibustion pretreatment;Myocardial ischemia-reperfusion;Ischemic preconditioning;Myocardial autophagy proteins796|1382|19更新时间：2023-08-11
- 摘要：Objective To observe the effect of electroacupuncture(EA)of"Fenglong"(ST 40)and"Sanyinjiao"(SP6)on lipid metabolic disorder,insulin resistance(IR)and expression of sterol regulatory element blinding protein-1(SREBP-1)c and fatty acid synthase(FAS)proteins in the liver tissue in hyperlipidemia rats with IR,so as to reveal its mechanisms underlying improvement of IR.Methods Forty male SD rats were randomly divided into blank control,model,medication and EA groups(n=8 in each group).The IR model was established by feeding the rat with high-fat diet.Rats of the medication group were treated by intragastric administration of pioglitazone(10 mL/kg).For rats of the EA group,EA(2 Hz/100 Hz,1 mA)was applied to bilateral ST 40 and SP 6,once daily for 14 days.The insulin sensitivity index(ISI)was assessed by calculating 60-120 min glucose infusion rate(GIR 60-120)with euglycemic hyperinsulinemic clamp in reference to Kraegen's and colleagues' methods.Fasting blood samples(10 mL)were collected and analyzed for fasting blood glucose(FBG)using enzyme method,serum fasting insulin(FINS)using ELISA,free fatty acid(FFA)using spectrophotometry,and total triglyceride(TG)and total cholesterol(TC)employing glycerine phosphate oxidase peroxidase(GPO-PAP)assay,low density lipoprotein(LDL),high density lipoprotein(HDL)levels using combined filiter paper activity and lipase activity methods,respectively.The IR level was assessed by calculating homeostatic model assessment of insulin resistance(HOMA-IR)using the formula(FBG×FINS)/22.5.The expression levels of SREBP-1 cand FAS proteins in the liver tissue were detected by Western blot.Results Following modeling,the GIR60-120 and serum HDL were significantly decreased(P<0.01),and the HOMA-IR,serum FBG,FINS,FFA,TG,TC and LDL,and the expression levels of hepatic SREBP-1 cand FAS proteins were significantly increased in comparison with the blank control group(P<0.01).After the intervention,the decreased GIR 60-120 and serum HDL levels were considerably up-regulated(P<0.01),and the increased FBG,FINS,FFA,TG,TC and LDL,and hepatic SREBP-1 cand FAS protein levels were notably down-regulated in both EA and medication groups relevant to the model group(P<0.05,P<0.01).No significant differences were found between the EA and medication groups in all the indexes mentioned above(P>0.05).Conclusion EA intervention is able to improve the disorder of lipid metabolism of IR rats,which may be associated with its effects in reducing the expression of SREBP-1 cand FAS proteins and in lowering the synthesis of fatty acid.关键词：Electroacupuncture;Hyperlipidemia;Insulin resistance;Disorder of lipid metabolism;Hepatic sterol regulatory element blinding protein-1(SREBP-1)c;Fatty acid synthase(FAS)759|399|10更新时间：2023-08-11
- 摘要：Objective To observe the effect of electroacupuncture(EA)on mechanical hyperalgesia threshold(MHTs)and thermal hyperalgesia threshold(THTs)and content of proteinase-activated receptors 2(PAR 2)in dorsal root ganglia(DRG)in rats with inflammatory pain,so as to explore its peripheral mechanism underlying improvement of inflammatory pain.Methods The present study contains two parts.1)In the first part,27 male SD rats were randomized into sham hyperalgesic priming(shamHP)group and real hyperalgesic priming(HP)group(n=5 in the sham-HP group and n=6 in the HP group for the test of MHTs,n=8 in the two groups for the test of THTs).The sham-HP model was established by subcutaneous injection of normal saline into the left plantar part of the hind-paw,and the HP model established by subcutaneous injection of 1%carragenan(the first injection)into the same left hind paw,followed by injection of PGE2(100 ng/25μL,the second injection)into the dorsum pedis of the same hind paw 7 days after the first injection.The ipsilateral paw withdrawal latencies(MHTs and THTs)were detected before and 5 h,3 dand 6 dafter the first injection,0.5,4 and 24 hafter the second injection.2)In the second part,64 male SD rats were randomly divided into sham-HP,HP,sham-EA and EA groups(n=16 in each group).The sham-HP and HP models were made in the same way as the first part.Both"Zusanli"(ST 36)and"Kunlun"(BL 60)were punctured with filiform needles in the sham-EA group and also stimulated with EA:2 Hz/100 Hz,0.5-1.5 mA(0.5 mA increase per 10 min)for 30 min in the EA group,1 time/d for7 d.Both ipsilateral MHTs and THTs were observed at the same time-points of the first part and the PAR 2 protein content in the L 4-L 6 DRGs was assayed by ELISA 24 hafter the second injection.Results 1)In the first part of the study,compared with the sham-HP group,the MHTs at 5 hand 3 d,and THT at 5 hafter the first injection,and MHTs,and THTs at 4 and 24 hafter the second injection were significantly decreased in the HP group(P<0.01,P<0.05).2)In the second part of the study,compared with the HP group,the MHTs at 4 and 24 hafter the second injection and the THTs at 3 dafter the first injection,4 and 24 hafter the second injection were significantly up-regulated in the EA group(P<0.01,P<0.05).The content of PAR 2 in the DRGs(L 4-L 6)was significantly higher in the HP group than in the sham-HP group(P<0.05),but considerably lower in the EA group than in the HP group(P<0.05).Conclusion EA can suppress hyperalgesia priming in inflammatory pain rats which may be related to its effect in down-regulating PAR 2 level in the lumbar DRGs.关键词：Electroacupuncture;Inflammatory pain;Hyperalgesic priming;Pain transformation;Proteinase-activated receptors 2;Lumbar dorsal root ganglia776|377|4更新时间：2023-08-11
- 摘要：Objective To observe the effect of electroacupuncture(EA)on the levels of Aβ1-40 and Aβ1-42 and neprilysin(NEP)protein in the temporal cortex of SAMP 8 mice with Alzheimer's disease(AD),so as to explore its mechanism underlying improvement of AD based on the theory of"mutual assistance of kidney and brain"in traditional Chinese medicine.Methods Eighteen male SAMP 8 mice were randomly assigned to 3 groups:model,EA and medication(memantine,n=6/group),and 6 male homologous SAMR 1 mice were used as the normal control group.According to the"mutual assistance of kidney and brain"theory,EA(2 Hz,0.6 mA)was applied at"Baihui"(GV 20),bilateral"Shenshu"(BL 23)and"Taixi"(KI 3)for 15 min,once daily for8 consecutive weeks.Mice of the medication group were treated with intragastric administration of memantine(20 mg·kg-1·d-1)for 8 weeks.The contents of Aβ1-40 and Aβ1-42 in the temporal cortex were assayed using ELISA,and the expression of NEP protein in the temporal cortex was detected using immunohistochemistry and Western blot(WB),separately.Results The contents of Aβ1-40 and Aβ1-42 were significantly higher in the model group than in the control group(P<0.05),and notably lower in both EA and medication groups than in the model group(P<0.05).WB assay showed that the expression level of NEP was significantly down-regulated in the model group relevant to the control group(P<0.05),and obviously up-regulated in both EA and medication groups relevant to the model group(P<0.05).No significant differences were found between the EA and medication groups in the contents of Aβ1-40 and Aβ1-42 and in the up-regulated expression levels of NEP protein(P>0.05).Immunohistochemistry stain showed that NEP-positive products mainly expressed in the perikaryon of neurons of the temporal cortex.Conclusion EA intervention based on"mutual assistance of kidney and brain"theory has a good efficacy in up-regulating NEP expression and down-regulating Aβ1-40 and Aβ1-42 levels in the temporal cortex of AD mice,suggesting apotential effectiveness in the prevention and treatment of AD.关键词：Alzheimer's disease;Electroacupuncture;Aβ;Neprilysin;Cerebral cortex;Kidney and brain659|409|9更新时间：2023-08-11
- 摘要：Objective To observe and compare the effects of electroacupuncture(EA)at"Tianshu"(ST 25)and"Neiguan"(PC 6)for colonic motility and the expression of colon dopamine D 2 in irritable bowel syndrome(IBS)rats,and to explore the specificity of different meridians and different acupoints.Methods Forty Wistar newborn rats were randomly divided into blank,model,Tianshu and Neiguan groups.Separation of mother and child and acetic acid coloclyster combined with colorectal distension were used to establish IBS model in the model,Tianshu and Neiguan groups.At the age of 9 weeks,EA at bilateral ST 25 and PC 6 were applied in the corresponding groups 5 times,once every other day.After the intervention,the Bristol fecal score,the latent period of abdominal retraction reflex and the number of contraction waves were recorded.The expression of dopamine D 2 receptor was detected by immunohistochemistry.Results Compared with the blank group,the Bristol fecal score of the model group was higher(P<0.01),the 1 st contraction wave latent period was shorter(P<0.01),the number of contraction waves in 90 sincreased(P<0.01),the immunoreactive expression of D 2 receptor in colon decreased(P<0.01).Compared with the model group,the Bristol fecal scores of the Tianshu and Neiguan groups decreased(P<0.01),the 1 st contraction wave latent periods were longer(P<0.01),the numbers of contraction waves in 90 sdecreased(P<0.01),the positive expressions of D 2 receptor in colon increased(P<0.01,P<0.05).Compared with the Tianshu group,the immunoreactive expression of D 2 receptor in the Neiguan group decreased(P<0.01).Conclusion EA at ST 25 and PC 6 can improve the symptoms of colonic motility in IBS rats.The effect of EA at ST 25 is better,which indicates that different meridians and different acupoints play specific effects.关键词：Irritable bowel syndrome;Tianshu(ST 25);Neiguan(PC 6);Dopamine D 2receptor792|582|9更新时间：2023-08-11
- 摘要：Objective To explore the underlying mechanism of acupoint catgut embedding in improving primary dysmenorrhea(PD)in rats based on functional activities of the neuro-endocrine-immune(NEI)network.Methods Forty female rats were equally randomized into blank control,PD model,medication,and acupoint catgut embedding groups.The PD model was established by subcutaneous injection of estradiol benzoate(0.5 mg/rat on the 1 st and 10 th d,and 0.2 mg/rat from 2 ndto 9 th d)and oxytocin(2 U/rat,i.p.).Rats of the medication group were treated by intragastric perfusion of fenbid(0.8 mL/rat,125 mg/100 mL),once daily for 10 days.The catgut embedding was applied to bilateral"Ciliao"(BL 32),"Sanyinjiao"(SP 6)and"Guanyuan"(CV 4)before modeling.The body writhing times in 30 minutes were recorded,plasmaβ-endorphin(β-EP)content,and prostaglandin E 2(PGE2)and prostaglandin F 2α(PGF_(2α))contents in the uterus tissue were assayed using ELISA,and the activity of natural killer cell(NK cell)in the spleen tissue was detected using 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2-Htetrazolium bromide(MTT)method after isolation and co-culture with K 562 cells.Results The body writhing times were notably more in the model group than in the control group(P<0.01),and obviously fewer in both medication and catgut embedding groups than in the model group(P<0.01).After modeling,the plasmaβ-EP and uterus PGE2 contents and splenic NK cell activity were significantly decreased(P<0.01),while the uterus PGF_(2α) content was evidently increased in the model group relevant to the control group(P<0.01).Following the treatment,plasmaβ-EP and uterus PGE2 contents and splenic NK cell activity were considerably up-regulated(P<0.01),and uterus PGF_(2α) content was markedly down-regulated in both medication and acupoint catgut embedding groups(P<0.01),suggesting an involvement of the NEI network in catgut embedding-induced improvement of PD.The therapeutic effect of catgut embedment was markedly superior to that of medication in up-regulating splenic NK cell activity(P<0.01).No significant differences were found between the medication and catgut embedding groups in the body writhing times within 30 min,and in the levels of plasmaβ-EP and uterus PGE2 and PGF_(2α)(P>0.05).Conclusion The acupoint catgut embedding has a significant efficacy in relieving PD in rats,which may be related to its effect in up-regulating plasmaβ-EP,uterus PGE2 contents and splenic NK cell activity and in down-regulating uterus PGF2αlevel.关键词：Primary dysmenorrhea;Acupoint catgut embedding;Plasmaβ-EP;Uterus PGE2/PGF2α;Splenic NK cell activity;Neuro-endocrine-immune network782|889|8更新时间：2023-08-11
- 摘要：Objective To observe the effect of warm acupuncture on behavior and contents of serum immunoglobulin E(IgE),interleukin-1β (IL-1β )and tumor necrosis factor-α(TNF-α)in allergic rhinitis(AR)rats,so as to explore its mechanism underlying improving AR.Methods Forty Wistar rats were randomly divided into four groups:control group,model group,medication group and warm acupuncture group(10 rats/group).The AR model was established by intraperitoneal injection of sensitization and nasal drip.The rats in the medication group were given fluticasone propionate nasal spray,daily for 10 days.Warm acupuncture was applied to"Fengchi"(GB 20),"Yintang"(GV 29),"Yingxiang"(LI 20)for 60 seconds,once daily for 10 days.Behavioral scores were used to evaluate behavioral changes in rats.Enzyme linked immunosorbent assay(ELISA)was used to detect the expression levels of serum IgE,IL-1β and TNF-α.Results Behavioral scores of the model group were significantly higher than those of the control group 0,3,7 and 10 days after modeling(P<0.05).After treatment,the behavioral scores of medication group and the warm acupuncture group were lower than those of the model group(P<0.05),and the score was more lower in the warm acupuncture group than in the medication group(P<0.05).Compared with the control group,the levels of serum IgE,IL-1β and TNF-αin the model group were all increased(P<0.01),while the levels of serum IgE,IL-1β and TNF-αwere decreased in the medication and warm acupuncture groups after treatment in comparison with the model group(P<0.05,P<0.01).Compared with the medication group,the levels of serum IgE,IL-1β and TNF-αwere significantly lower in the warm acupuncture group(P<0.05,P<0.01).Conclusion The expression levels of IgE,IL-1β and TNF-αwere elevated in serum after AR attack.Warm acupuncture can improve the symptoms of AR rats,which may be associated to its effect in inhibiting the expression of serum IgE,IL-1β and TNF-α.关键词：Warm acupuncture;Allergic rhinitis;Behavior;Immunoglobulin E795|440|2更新时间：2023-08-11
- 摘要：Objective To observe the effect of Tiaoshen Kaiyu acupuncture(regulating vitality and dredging stasis)combined with psychological intervention for treating mild depression after stroke.Methods Ninety-four patients were enrolled and were randomly divided into acupuncture(48 cases)and control(46 cases)groups.Patients in the control group were given standard treatment plus psychological intervention,while patients in the acupuncture group were treated with Tiaoshen Kaiyu acupuncture plus standard treatment and psychological intervention.Acupoints of Sishencong(EX-HN 1),Baihui(GV 20),and Yintang(EX-HN 3)were selected in the acupuncture group.Each group received treatment once daily,five times weekly,for a total of 6 weeks.A self-rating depression scale(SDS),Hamilton depression scale(HAMD),simplified Fugl-Meyer motor function assessment(FMA),and modified Barthel index(MBI)were used before and after treatment to evaluate the efficacy.Results After the treatment the four indexes were improved significantly compared with those before treatment in the acupuncture and control groups(P<0.01).The FMA and MBI scores in the acupuncture group were higher than those in the control group(P<0.05).The HAMD and SDS scores were significantly lower in the acupuncture group than in the control group(P<0.01).In both the acupuncture and control groups,the differences before and after treatment of the HAMD and FMA scores(rs=0.332,P<0.01)and the HAMD and MBI scores(rs=0.356,P<0.01)were positively correlated.Conclusion Tiaoshen Kaiyu acupuncture combined with psychological intervention is more effective than psychological intervention therapy alone.The efficacy is correlated with motor function and mild depression scores of patients after stroke.关键词：Post-stroke mild depression;Psychological intervention;Tiaoshen Kaiyu acupuncture(regulating vitality and dredging stasis)610|365|1更新时间：2023-08-11
- 摘要：Objective To assess the safety and efficacy of transcutaneous electrical acupoint stimulation(TEAS)for depression in late pregnancy and impacts on inflammatory cytokines.Methods A total of 150 pregnant women with depression in late pregnancy were randomized into a high intensity group(n=52),a low intensity group(n=49)and a control group(n=49).TEAS was applied at bilateral Neiguan(PC 6)and Shenmen(HT 7)for 6 weeks.The intensities of TEAS in the high intensity group,the low intensity group and the control group were 10,5 and 0 mA,respectively.During the process of TEAS,the blood pressure,pulse,uterine contraction and the fetal heart rate were recorded.Depression was evaluated by 24-item Hamilton depression scale(HAMD)before TEAS and after 2-week,4-week,6-week treatment.Serum levels of tumor necrosis factor-α(TNF-α),interleukin-1β(IL-1β)and IL-6 were detected by enzyme-linked immunosorbent assay(ELISA)before and after 6-week treatment.Delivery outcomes were observed.The correlation was analyzed between HAMD difference value and the difference values of TNF-α,IL-1βand IL-6,respectively.Results The blood pressure,pulse and fetal heart rate had no statistical significance before and after treatment in the three groups(P>0.05).The HAMD scores at all the time points were lower than that before treatment in the high intensity group(P<0.05),which were lower compared with those in the low intensity group and the control group(P<0.05).The HAMD score in the low intensity group decreased after 6-week treatment compared with that before treatment and was lower than that in the control group(P<0.05).The serum levels of IL-1βand IL-6 in the high intensity group decreased compared with those before treatment and were lower compared with those in the low intensity group and the control group after 6-week treatment(P<0.05).There was no significant difference in the deliver outcomes among the three groups(P>0.05).The variation of HAMD score did not have significant correlation with those of TNF-α,IL-1βand IL-6(P>0.05).Conclusion TEAS is safe and effective for depression in late pregnancy and can regulate the serum levels of IL-1βand IL-6 without influencing on delivery outcome.关键词：Transcutaneous electrical acupoint stimulation(TEAS);Depression;Late pregnancy;Inflammatory cytokines647|231|1更新时间：2023-08-11
- 摘要：Objective To observe the analgesic effect of deqi induced by needling at Sanyinjiao(SP 6)on primary dysmenorrheal(PD)patients with cold damp stagnation syndrome(CDSS).Method A total of 64 PD patients with CDSS experiencing abdominal pain(≥40 mm in visual analogue scale,VAS)were randomly assigned into deqi-expectation(DE)group(n=15)and no-deqi-expectation(NDE)group(n=49).On the first day of abdominal pain attack,bilateral SP 6 were punctured respectively with thicker needles with deeper insertion for deqi-expectation patients and thin filiform needles with shallow insertion for no-deqi-expectation patients.The needles were removed after 30 minutes,adeqi scale was used to evaluate the deqi condition.According to the results,patients in the DE group were further divided into deqi DE group and no-deqi DE group,patients in the NDE group were also divided into deqi NDE group and no-deqi NDE group.The VAS was used to evaluate the patients' abdominal pain severity before treatment and 0,10,20,30 min after acupuncture needle withdrawal.Results The rate of deqi in the DE group was higher than that in the NDE group(P<0.05).The VAS scores of abdominal pain in the four groups were decreased at all time-points after needle withdrawal compared with those before treatment(P<0.01),while the VAS score in the deqi DE group were lower than in the no-deqi NDE group 30 min after needle withdrawal(P<0.05).Conclusion The intervention method of thick needle,deep insertion and some manipulation is easier in inducing deqi than that of thin needle,shallow insertion and no manipulation.The analgesic effect of deqi is better than that of no-deqi for PD patients with CDSS.关键词：Deqi;Cold damp stagnation syndrome;Analgesic effect;Sanyinjiao(SP 6);Primary dysmenorrhea754|547|4更新时间：2023-08-11
- 摘要：Objective To observe the effect of acupuncture on inflammatory indices and symptoms in patients with acute pelvic inflammatory disease,and investigate its mechanism.Methods Seventy-nine patients with acute pelvic inflammatory disease were randomly assigned to a control group(n=37)given conventional treatment and an observation group(n=42)given conventional treatment and acupuncture therapy.In the observation group,acupionts of Zhongji(CV 3),Guanyuan(CV 4),Zigong(EX-CA 1),Zusanli(ST 36),Sanyinjiao(SP 6),etc.were selected.Each group received treatment once daily,for a total of 7 days.Tumor necrosis factor(TNF)-α,interleukin(IL)-10 and C-reactive protein(CRP)in the serum,white blood cell(WBC)and neutrophil counts,size of pelvic mass and depth of pelvic effusion,and clinical symptoms were assayed pretreatment and on days 3 and 7.Results WBC and neutrophils were significantly decreased after treatment in both groups(P<0.05),and more in the observation group than in the control group(P<0.05).After treatment,the size of pelvic mass and depth of effusion were less in both groups(P<0.05),and the efficacy in the observation group was superior to that in the control group(P<0.05).In the observation group,serum TNF-α,and CRP on day 3 and day 7 were significantly lower than those before treatment(P<0.05).Serum TNF-αand CRP were significantly down-regulated in the observation group compared with those in the control group on both day 3 and day 7(P<0.05).In the observation group,serum IL-10 was higher on both day 3 and day 7 than that before treatment(P<0.05),and was statistically different from that in the control group on both days(P<0.05).The clinical efficacy in the observation group was superior to that in the control group(95.24% vs 81.08%,P<0.05).Conclusion Acupuncture can regulate the levels of inflammatory markers in patients with acute pelvic inflammatory disease,and improve clinical symptoms.关键词：Acupuncture;Acute pelvic Inflammatory disease;Inflammatory cytokines;Efficacy708|357|1更新时间：2023-08-11
- 摘要：Facial nerve injury results in facial muscle movement disorders that interferes with patient's life.Acupuncture is an effective therapy for facial nerve injury,but its mechanism has not been clarified.The evidence supports that acupuncture can accelerate the repair of facial nerve injury by adjusting the electric wave of patient's facial muscle,improving facial blood circulation,and promoting the expression of cell and protein molecule.关键词：Acupuncture;Facial nerve injury;Mechanism of action;Review834|1226|8更新时间：2023-08-11
- Postal code：100700
- Tel：010-64089344,84014607 Email：zcyjbjb@vip.163.com
- Technical support is provided by Beijing Founder electronics co., LTD 京ICP备05017590号-8
京公网安备11010802020460号 - It is recommended to read the content of this site in Chrome&IE9+. Please switch to extreme mode in browser 360.
- Cookies We use cookies to help provide and enhance our service and tailor content. By continuing, you agree to the use of cookies.
0