最新刊期
卷 43 ， 期 2 ， 2018
- 摘要：Moxibustion,one of the traditional Chinese medicine therapy,plays an important role in the treatment of a variety of clinical conditions,particularly the chronic and deficiency problems.In the present paper,the author reviewed the history of development of moxibustion therapy,and the related materials and heating temperature in ancient China,and also reviewed the history of heating therapy(similar to moxibustion)appearing in ancient Egypt,Greek,Libya,India,Europe,etc.The author thinks that the efficacy of moxibustion intervention mainly depends on the heating temperature and the heated area of the skin(not the heating materials)according to his own research group's experimental outcomes.Some problems of moxibustion should be noted,for example,the ignited moxa-smoke induced environmental contamination which may lead to chronic injury particularly to the health of the related practitioners.The author forecasts that some succedaneous materials of mugwort as physical heating energy(mechanical,electrical,microelectronic,solar energy),chemical,biological and medical heating reagents(acupoint receptor-activator),etc.,high technique medical devices are probably developed in the future,minimizing some defects of moxa and expanding clinical application of moxibustion therapy.关键词：Efficacy of moxibustion;Heating materials;Heating temperature;Heating area651|1079|8更新时间：2023-08-11
- 摘要：Objective To observe the effect of different-doses of herbal cake-partitioned moxibustion(Moxi)on histopathological changes of the damaged colon tissue in rats with ulcerative colitis(UC),so as to select an optimal dosage of Moxi in the treatment of UC.Methods Sixty-three male Sprague Dawley(SD)rats were randomized into 7 groups:normal control,model,medication,and 1,2,3 and 4 moxa-cone Moxi(n=9 rats per group).The UC model was developed by subcutaneous injection of emulsion(1 mL)containing colon mucosa-prepared protein suspension and complete Freund's adjuvant into the toes,groin and back.On the 38 th day,enema of 3%formalin and the aforementioned emulsion was used.Herbal-cake(composed of monkshood,cinnamon,etc.)partitioned Moxi with 1 or 2 moxa-cones(about 5 min/cone)was applied to bilateral"Tianshu"(ST 25)once daily or once every other day.The rat's general conditions(diet,movement,response ability,stool,and body weight)were observed,and histopathological changes(adhesion,ulcer formation and inflammation)of colon tissues were examined after hematoxylin-eosin(HE)staining,and scored(histopathological score).Gross score was given according to the severity of adhesion,ulcer formation and inflammation of colonic tissues under stereo microscope.The average optical density(AOD)values of colonic mucins were detected after periodic acid-schiff(PAS)staining,and those of the sulfated mucus content detected after high iron diamine-alcian blue(HID-AB)staining.Results Compared with the normal group,rats in the model group presented loose stool,or with pus and blood,and slowly increased body weight(P<0.01),obvious congestion of colon with ulcer spots or continuous superficial ulcer regions which had irregular glandular cavities,swelling and serious inflammatory infiltration in lamina propria and submucosa,and increased score of colon tissue damage(P<0.01).PAS and HID-AB staining showed a marked decrease of AOD values of colonic mucins and sulfated mucus in the model group relevant to the normal control group(P<0.01),suggesting a reduction of mucus secretion of intestinal glands.Following the intervention,rats in the Moxi groups presented an increase of the body weight,formed feces,and an improvement of the damaged colon tissues as mucosal healing and inflammatory reduction,and a marked decrease of the damage score relevant to the model rats.No significant differences were found in the gross scores among the medication,1,2,3 and 4 moxa-cone groups(P>0.05).The histopathological scores were significantly lower in the1 and 4 moxa-cone Moxi groups than in the medication group(P<0.05,P<0.01);and significantly lower in the 1,3,4 moxacone Moxi groups than in the 2 moxa-cone Moxi group(P<0.05,P<0.01).PAS staining showed a significant increase of the AOD values of colonic mucins in the 1,2,3 and 4 moxa-cone and medication groups relevant to the model group(P<0.01);and the AOD values of colonic mucins in the 1,3,4 moxa-cone Moxi groups were significantly increased than that in the 2 moxa-cone Moxi group(P<0.05,P<0.01).HID-AB staining showed that the AOD values of sulfated mucus content were significantly higher in the 2 and 4 moxa-cone Moxi groups than in the 3 moxa-cone Moxi group(P<0.01).The two-level two-factor factorial analysis showed an interaction existed between the moxa-cone number and Moxi frequency in reducing the gross score and histopathological score and in facilitating colonic mucin and sulfated mucus secretion.The histopathological score of the 4 moxa-cone Moxi group was significantly lower than that of the 2 moxa-cone Moxi group(P<0.05),and the sulfated mucus content was significantly higher in the 4 moxa-cone group than in the 3 moxa-cone group(P<0.01).The effect of Moxi given on alternate days was superior to that of daily Moxi in improving colonic histological damage.Conclusion Herbal cake-partitioned moxibustion at ST 25 can promote repair of the damaged colonic tissue and secretion of mucin in UC rats.The number of moxa cones and intervention frequency affect the efficacy of Moxi in improving histopathological changes.The Moxi intervention on alternate days and with 2 moxa-cones every time is recommended.关键词：Herb-partitioned moxibustion;Ulcerative colitis;HE staining;Colonic mucins;Sulfated mucus;Moxibustion dosage638|738|7更新时间：2023-08-11
- 摘要：Objective To study the protective effect of moxibustion for tripterygium-induced premature ovarian failure(POF)and its underlying mechanisms in rats.Methods Forty-five female SD rats were randomly divided into normal control,POF model and moxibustion groups(n=15/group).The POF model was induced by intragastric administration of Triptolide(40 mg/kg),once daily for 6 weeks.From the 4 th week after modeling,moxibustion was given at"Guanyuan"(CV 4)and bilateral"Sanyinjiao"(SP 6)for 10 min,once daily for 3 weeks.Pathological changes of ovary tissues were determined by hematoxylin-eosin(HE)staining.The serum estradiol(E2),luteinizing hormone(LH),follicle-stimulating hormone(FSH),interleukin-6(IL-6)and interleukin-1β(IL-1β)contents were measured by enzyme-linked immunosorbent assay(ELISA).The expression levels of phosphatidyl inositol 3-kinase(PI 3 K),protein kinase B(Akt)and mammalian target of rapamycin(mTOR)proteins of the ovarian tissue were detected by Western blot.Results After modeling,HE staining showed that the numbers of ovarian follicles and follicular granulocytes and corpora luteum layers were decreased,and the number of corpora atretica was increased in the model group.The content of serum E2 was markedly decreased and those of serum LH,FSH,IL-6 and IL-1βwere markedly increased in the model group(P<0.01),and the expression levels of ovarian p-PI 3 K,p-Akt and p-mTOR were markedly increased after modeling relevant to the control group(P<0.01).Following moxibustion,the pathological damage of ovarian tissue was improved,the contents of serum LH,FSH,IL-6,IL-1β,and the levels of p-PI 3 K,p-Akt and p-mTOR proteins in the ovarian tissue were significantly decreased(P<0.05,P<0.01),and the content of serum E2 was markedly increased(P<0.05)in comparison with the model group.Conclusion Moxibustion can improve POF in POF rats,which may be related to its actions in inhibiting PI 3 K/Akt/mTOR signaling,down-regulating serum IL-6,IL-1β,and regulating serum hormones.关键词：Moxibustion;Premature ovarian failure;Phosphatidyl inositol 3-kinase/protein kinase B/mammalian target of rapamycin protein(PI 3K/Akt/mTOR);Serum hormones;Pro-inflammatory cytokines687|1512|9更新时间：2023-08-11
- 摘要：Objective To observe the effect of moxibustion on cardiac function and the expression of B-cell lymphoma-2(Bcl-2),Bcl-2 associated X(Bax),Fas,Fas ligand(FasL)in cardiomyocytes of chronic heart failure(CHF)rats,so as to explore its underlying mechanisms in preventing and treating CHF.Methods SD rats were randomly divided into normal control,model,moxibustion,Captopril and moxibustion + Captopril(M+C)groups(n=12 rats/group).The CHF model was established by intraperitoneal injection of Adriamycin(ADR,from 1 to 4 mg/kg,once every other day for 15 days).Mild moxibustion was applied to bilateral"Feishu"(BL 13)and "Xinshu"(BL 15).Rats of the Captopril group was treated by gavage of Captopril suspension(5 mg/mL,25 mL/kg),and those of the M+C group treated by the combined two methods.All the treatments were given once a day for 3 weeks.The general conditions and behaviors of rats were observed.The left ventricular mass index(LVMI)and right ventricular mass index(RVMI)were detected for assessing the cardiac performance.Morphological changes of myocardium were observed by HE staining.Enzyme linked immunosorbent assay(ELISA)was used to detect the concentrations of Btype natriuretic peptide(BNP)and precursor N-terminal pro-brain natriuretic peptide(NT-pro BNP)in the serum.The expression levels of Bcl-2,Bax,Fas and FasL of the left ventricle of heart were detected by Western blot.Results After modeling,the pathological changes of myocardium(as myocardial cell swelling with vacuoles,myocardial fibre breakage,etc.)were obvious,the LVMI,RVMI,serum BNP and NT-pro BNP concentrations,and myocardial Bax,Fas and FasL protein expression levels were significantly increased in the model group compared with the normal group(P<0.01),while the expression level of Bcl-2 was significantly down-regulated(P<0.01).Following the interventions,the myocardial injury was reduced,both LVMI and RVMI,serum BNP concentration and Bax,Fas and FasL expression levels in the three treatment groups,and serum NT-pro BNP concentration in the moxibustion and M+C groups were significantly decreased(P<0.05,P<0.01),while the myocardial Bcl-2 protein levels in the three treatment groups were significantly increased relevant to the model group(P<0.01).Comparison among the three treatment groups showed that the effects of moxibustion+ Captopril were significantly superior to those of simple moxibustion and simple Captopril in suppressing CHF-induced increased expression of myocardial Bax,Fas and FasL,and in lessening CHF-induced decrease of Bcl-2 level(P<0.05,P<0.01).No significant differences were found among the three treatment groups in down-regulating LVMI and RVMI,and serum BNP content(P>0.05).Conclusion Moxibustion can reduce myocardial injury and improve cardiac function in CHF rats,which may be related to its effects in down-regulating the expression of myocardial Bax,Fas and FasL proteins,and up-regulating the expression of Bcl-2 protein to inhibit cardiomyocyte apoptosis.关键词：Moxibustion;Chronic heart failure;Myocardial apoptosis;Histopathological changes;Cardiac performance799|422|7更新时间：2023-08-11
- 摘要：Objective To observe the effect of herbal-cake-separated moxibustion on blood lipid levels and expression of peroxisome proliferator-activated receptorγ(PPARγ)and scavenger receptor B 1(SR-B 1)proteins and genes in liver of hyperlipidemia atherosclerosis rabbits,so as to explore its mechanism underlying anti-atherosclerosis formation.Methods Forty male New Zealand white rabbits were randomly divided into normal control,model,moxibustion and Simvastatin groups(n=10 rabbits in each group).The hyperlipidemia atherosclerosis model was established by high cholesterol diet and propylthiouracil for12 weeks.Herbal-cake-separated moxibustion was applied to"Juque"(CV 14),and bilateral"Tianshu"(ST 25),"Fenglong"(ST 40)(point group 1),and bilateral"Xinshu"(BL 15),"Ganshu"(BL 18)and "Pishu"(BL 20)(point group 2).The two groups of points were used alternately.Simvastatin(1.96 mg·kg(-1)·d(-1)·d(-1))mixed in the forage was given to rabbits of the Simvastatin group.Both moxibustion and medication treatments were given once daily for continuous 4 weeks.Total cholesterol(TC),triglyceride(TG),low density lipoprotein cholesterol(LDL-C)and high density lipoprotein cholesterol(HDL-C)levels in plasma were detected by using an automatic biochemistry analyzer.The expression levels of PPARγand SR-B 1 proteins and genes in the hepatic tissue were determined by Western blot and reverse transcription-polymerase chain reaction,separately.Results After modeling,plasma TC,TG and LDL-C levels in the model group were significantly increased(P<0.01),and the levels of plasma HDL-C and hepatic PPARγand SR-B 1 protein and mRNA expression were obviously down-regulated relevant to the normal group(P<0.01).Compared with the model group,plasma TC,TG and LDL-C levels were significantly decreased(P<0.01),and plasma HDL-C and hepatic PPARγand SR-B 1 protein and mRNA levels were significantly up-regulated in the two treatment groups(P<0.01,P<0.05).Conclusion Herbal-cake-separated moxibustion can regulate blood lipid levels and suppress hyperlipidemiainduced decrease of expression of hepatic PPARγand SR-B 1 proteins and genes in hyperlipidemia atherosclerosis rabbits,which maybe contribute to its action in anti-atherosclerosis through promoting reversal of cholesterol.关键词：Herbal-cake-separated moxibustion;Hyperlipidemia;Atherosclerosis;Peroxisome proliferator-activated receptor γ;Scavenger receptor B 1698|440|4更新时间：2023-08-11
- 摘要：Objective To observe the effect of herbal cake-separated moxibustion on blood lipid-apoprotein levels and the expression of Toll-like receptor 2(TLR 2),TLR 4 and nuclear factor kappa B(NF-κB)mRNAs in atherosclerotic(AS)vulnerable plaques of hyperglycemia rabbits,so as to explore its mechanism underlying improvement of atherosclerosis.Methods Sixty New Zealand rabbits were randomly divided into 5 groups:control,model,direct moxibustion,herbal-cake-separated moxibustion and medication groups(n=12 rabbits in each group).The AS vulnerable plaque model was established by high-fat forage feeding plus balloon-induced abdominal aorta injury and gene transfection of Ad 5-p 53 recombinant vector.Direct moxibustion or herbal-cake-separated moxibustion was applied to"Juque"(CV 14)and bilateral"Tianshu"(ST 25),"Fenglong"(ST 40),or bilateral"Xinshu"(BL 15),"Pishu"(BL 20)and"Ganshu"(BL 18)for 15-20 min every time.The medication group was treated by feeding Atorvastatin.All the treatments were conducted once daily for 8 weeks.Plasma total cholesterol(TC)and triglyceride(TG)contents were detected by enzyme method,high-density lipoprotein(HDL)and low-density lipoprotein(LDL)contents detected by colorimetric determination,and plasma apolipoprotein A(Apo-A)and apolipoprotein B(Apo-B)levels determined by electrophoretic method.The pathological changes of vulnerable plaque and the aortic intima and media thickness were observed under light microscope after H.E.staining.The expression levels of TLR 2,TLR 4 and NF-κB mRNAs in AS plaques were determined by quantitative real-time PCR.Results After modeling,the levels of plasma TC,TG,LDL and Apo-B in the model group were remarkably increased(P<0.01),and Apo-A and HDL/LDL were significantly decreased in comparison with the control group(P<0.01).Additionally,the aortic intima and media thickness and the expression levels of TLR 2,TLR 4 and NF-κB mRNAs in AS plaques were significantly increased(P<0.01).After the treatment,the elevated levels of plasma TC,TG,LDL and Apo-B,the aortic intima thickness and media thickness,and the expression levels of TLR 2,TLR 4 and NF-κB mRNAs in the 3 treatment groups were significantly down-regulated in comparison with the model group(P<0.05,P<0.01),while the decreased levels of Apo-A and HDL/LDL were considerably increased(P<0.01).Comparison among the 3 treatment groups showed that the therapeutic effects of the herbal-cake-separated moxibustion and medication were significantly superior to those of the direct moxibustion in down-regulating the levels of TC,TG,LDL,Apo-B,TLR 2 mRNA,TLR 4 mRNA and NF-κB mRNA,and reducing the thickness of the aortic intima and media,as well as in up-regulating the levels of Apo-A and HDL/LDL(P<0.05,P<0.01).No significant differences were found between the herbal-cake-separated moxibustion and medication groups in the above-mentioned indexes(P>0.05).Conclusion Herbal-cake-separated moxibustion has a positive role in stabilizing AS vulnerable plaque in hyperglycemia rabbits,which may be associated with its effects in regulating blood lipid-apolipoprotein levels and inhibiting the expression of TLR 2,TLR 4 and NF-κB mRNAs in vulnerable plaques.关键词：Herbal-cake-separated moxibustion;Atherosclerotic vulnerable plaques;Plasma lipid-apolipoproteins;Toll-like receptor 2(TLR 2);Toll-like receptor 4(TLR 4);Nuclear factor kappa B(NF-κB)616|255|4更新时间：2023-08-11
- 摘要：Objective To study the effect of moxa-smoke inhaling on the respiratory system,so as to provide experimental data and theoretical basis for evaluating the safety of moxa-smoke inhaling during moxibustion treatment.Methods A total of 48 SD rats were randomized into control,low,medium and high moxa-smoke-concentration groups(n=12 in each group).The low,medium and high concentrations of smoke were controlled in(0.11±0.05)mg/m3,(0.23±0.05)mg/m3 and(0.53±0.05)mg/m3 respectively in each of 3 glass boxes(with reference to the level of PM 2.5).The smoking was conducted 4 hours each time,twice a day for 100 days.The normal group did not receive any moxa-smoke inhaling.The histopathological changes of lung and bronchial tissues were detected by H.E.stainning,and the contents of TNF-αand IL-1βof plasma,bronchoalveolar lavage fluid(BALF)and lung tissue detected by ELISA.The levels of forced vital capacity(FVC),forced expiratory volume(FEV),FEV 0.3/FVC(0.3=the 0.3 rd second),maximal mid-expiratory flow rate(MMEF),peak expiratory flow(PEF)were detected by animal pulmonary function analysis system.Results After 100 days' moxa-smoke inhaling,the contents of TNF-αin the plasma,BALF and lung tissues and IL-1βin the lung tissue of the low,medium and high concentration moxa-smoke groups,and IL-1βin the plasma and BALF of the medium and high concentration groups were significantly increased relevant to the control group(P<0.05,P<0.01).H.E.stain showed various inflammatory changes in the lungs and trachea tissues,including obvious fusion of pulmonary alveoli,lymphocyte infiltration,increase of capillary permeability,red blood cell exudation,etc.in the high concentration group,these situations were milder in the medium concentration group and were not obvious in the low concentration group.Compared with the control group,there were no significant changes in the FVC,FEV,FEV 0.3/FVC,MMEF and PEF of lung function in the three concentration groups(P> 0.05).Conclusion Long term inhalation of high concentration of moxa-smoke may lead to inflammatory injury in the lung and bronchial tissues but has no significant effect on the respiratory function in rats.Nevertheless,agood air-ventilation during moxibustion in a treatment room is necessary.关键词：Moxibustion therapy;Moxa-smoke inhale;Lung function;Respiratory system;Inflammatory injury;Safety694|643|7更新时间：2023-08-11
- 摘要：Moxibustion is an effective therapy for treatment of a lot of clinical problems,but the ignited moxa-induced smoke containing harmful substances may bring about indoor air pollution to affect both patients' and medical workers' health.However,there is no standards about controlling indoor air quality(IAQ)for moxibustion rooms in China.In the present study,the authors reviewed newly-published articles about some substances released from moxa smoke as inhalable particles(PM 10 and PM 2.5),formaldehyde,benzene,methylbenzene,xylene,bene[α]pyrene,total volatile organic compounds,CO,CO2,NO,SO2,NH3,O3,etc.some of which affect IAQ.On this account,the authors put forward some strategies for controlling IAQ in moxibustion clinics including setting united safe standards,enhancing ventilation,controlling moxibustion material quality and strengthening scientific research on the safety of moxa smoke control,fully playing the superiority of moxibustion therapy and reducing its unfavorable aspects in clinical practice in the future.关键词：Moxibustion;Moxa smoke;Indoor air quality;Control strategy856|742|2更新时间：2023-08-11
- 摘要：Objective To observe the clinical effect of thunder-fire moxibustion in the treatment of qi deficiency-induced fatigue in breast cancer patients undergoing chemotherapy.Methods Sixty breast cancer patients undergoing chemotherapy were randomly divided into thunder-fire moxibustion(Moxi)and conventional nursing(nursing)groups(n=30 in each group).Patients in the Moxi group were treated with thunder-fire moxibustion applied to the back part of body from Pishu(BL 20)to Qihaishu(BL 24)on the bilateral sides and to the abdominal part from Zhongwan(CV 12)to Guanyuan(CV 4)for 30 min,once a day for14 days.Patients in the nursing group were treated with health education and conventional nursing care.The simple fatigue scale,traditional Chinese medicine(TCM)syndrome score,clinical curative effect were observed before and after the treatment,and white blood cell(WBC)count was observed 5 days ofter chemotherapy and after the treatment respectively.Results After the treatment,the simple fatigue scales and TCM syndrome scores were significantly decreased and WBC counts were significantly increased in both groups relevant to their individual pre-treatment(P<0.01).The therapeutic effect of the Moxi group was apparently superior to that of the nursing group in lowering the simple fatigue scale and TCM syndrome score and in up-regulating WBC count(P<0.01,P<0.05).The total effective rate of the Moxi group was significantly higher than that of the nursing group(83.3%[25/30]vs 36.7% [11/30],P<0.01).Conclusion Thunder-fire moxibustion can effectively relieve the degree of fatigue and the symptoms of qi deficiency in breast cancer patients undergoing chemotherapy.关键词：Thunder-fire moxibustion;Breast cancer;Cancer-related fatigue;Clinical research656|1240|2更新时间：2023-08-11
- 摘要：Objective To observe the effect of manual acupuncture stimulation of different layers(skin,muscle,peritoneum,sub-peritoneum)of"Tianshu"(ST 25)region on proximal colonic pressure in normal rats.Methods Forty-eight male SD rats were divided into 6 groups:all layer-needling,brushing,cutaneous needling,muscular needling,peritoneum-needling and sub-peritoneum-needling groups(n=8 in each group).Manual needling or brushing was applied to "Tianshu"(ST 25)region.The colonic internal pressure was measured by using an amplifier and a pressure transducer-connected balloon which was implanted into the colonic cavity about 6 cm from the ileocecal valve.For rats of the all-layer needling group,an acupuncture needle was inserted into ST 25 about 1 cm deep and rotated for a while,for rats of the brushing group,a Chinese calligraphy brush pen was used to brush the skin hair for 1 min.For rats of the rest 4 groups,an acupuncture needle was inserted into the skin,muscle layer after cutting open the skin(about 0.1 cm),the peritoneum layer after cutting open the skin and muscle layers,and the sub-peritoneum layer after cutting open the skin,muscle and peritoneum layers,respectively,and rotated using the uniform reinforcing-reducing technique for about 1 min at a frequency of 120 twirlings per minute every time.Results During manual needling stimulation of the full layers,cutaneous layer,muscle layer,peritoneum layer and the sub-peritoneum layer of bilateral"Tianshu"(ST 25),the internal pressure of proximal colon was significantly decreased relevant to pre-stimulation in each group(P<0.05),and there were no significant differences between bilateral sides needling stimulation in the decreased pressure levels(P>0.05).During hair brushing of ST 25 region,the colonic pressure was observably increased relevant to pre-needling stimulation(P<0.05).One min after the acupuncture stimulation,the decreased pressures maintained in needling the all-layer on the left side,needling the skin on the right side,needling the peritoneum layer on both sides,and needling the sub-peritoneum layer on both sides relevant to the brushing group of the same side(P<0.05).Conclusion Manual acupuncture stimulation of each layer tissue of ST 25 on both sides may lower internal pressure of proximal colon in normal rats,suggesting their involvement of acupuncture effect in relaxing proximal colonic contraction.关键词：Manual acupuncture stimulation;Tianshu(ST 25);Different layer tissues;Internal pressure of proximal colon635|311|5更新时间：2023-08-11
- 摘要：Objective To observe the clinical efficacy of intradermal needle-embedding therapy in the treatment of dysphagia in stroke patients.Methods A total of 80 stroke patients with dysphagia were randomly divided into treatment group and control group(n = 40 in each).The control group was treated with conventional medicines,neuromuscular electrical stimulation of the bilateral midlines of the neck and swallowing function training,and the treatment group treated by intradermal needleembedding at Lianquan(CV 23),Jialianquan-point,Yifeng(TE 17),Ashi-point,etc.(once every other day for 20 days)on the basis of the treatments used in the control group.Swallowing function(0-10 points scaling,the bigger the better)and surface electromyography(sEMG)of the bilateral suprahyoid muscles and infrahyoid muscles in the relaxing,nothing swallowing and water-swallowing conditions were tested before and after the treatment.Results After treatment,the swallowing scores were significantly increased in both groups compared with those of their individual pre-treatment(P<0.05),suggesting an improvement of swallowing function.During relaxing,nothing swallowing and water-swallowing conditions,the peak amplitudes of sEMG were considerably increased in both groups relevant to those of their individual pre-treatment(P<0.05).The swallowing function score,and maximum amplitudes of sEMG during relaxing,nothing swallowing and water-swallowing conditions were significantly higher in the treatment group than in the control group(P<0.05),suggesting a better efficacy of intradermal needle-embedding treatment.Conclusion Intradermal needle-embedding can significantly improve the swallowing function of stroke patients with dysphagia.关键词：Dysphagia of stroke;Intradermal needle embedment;Neuromuscular electrical stimulation;Surface electro-myogram597|596|3更新时间：2023-08-11
- 摘要：Objective To observe the therapeutic effect of balance acupuncture combined with motor relearning training for upper limb and hand functions of stroke patients.Methods Sixty-two stroke patients were randomly divided into balance acupuncture group(n=31)and routine acupuncture group(n=31).For patients of the balance acupuncture group,Piantan,Jiantong and Wantong points on the healthy side were used.When Jiantong point taken,the acupuncture needle was removed after the patient experienced an electric shock-like spreading needling sensation.When Wantong point employed,the needle was removed after the patient experienced a local,intensified or spreading needling sensation.When Piantan point used,the needle was retained after the patient experienced an electric shock-like needling sensation,then,the motor relearning training was conducted,and the needle was removed immediately after the training.For patients of the routine acupuncture group,Jianyu(LI 15),Jianzhen(SI 9),Quchi(LI 11),etc.were needled with the needles retained for 30 min after getting needling sensations.The motor relearning training was also carried out after removal of the needle.The treatment in both groups was performed once daily,6 days a week,and lasted for 8 weeks.The Fugl-Meyer score and motor function scale(MAS)of the upper limb,and the fine performance score and motor function score of the hand were assessed before and after the treatment.Results Following treatment,the Fugl-Meyer score and MAS of the upper limbs,and the motor function score and fine performance score of the hand were significantly increased in both groups compared with pre-treatment in each group(P<0.05),suggesting a functional improvement of both upper limb and hand.The therapeutic effect of the balance acupuncture was obviously superior to that of routine acupuncture in improving functions of both the upper limb and hand(P<0.05).Conclusion Balance acupuncture combined with motor relearning training is helpful to improve the comprehensive function of the upper limb and hand in stroke patients.关键词：Stroke;Balance acupuncture;Motor relearning training program;Upper-limb motor function;Hand motor function608|429|4更新时间：2023-08-11
- 摘要：Objective To attempt to establish an objective quantitative indicator to characterize the trigger point activity,so as to evaluate the effect of dry needling on myofascial trigger point activity.Methods Twenty-four male Sprague-Dawley rats were randomly divided into blank control group,dry needling(needling)group,stretching exercise(stretching)group and needling plus stretching group(n=6 per group).The chronic myofascial pain(trigger point)model was established by freedom vertical fall of a wooden striking device onto the mid-point of gastrocnemius belly of the left hind-limb to induce contusion,followed by forcing the rat to make a continuous downgrade running exercise at a speed of 16 m/min for 90 min on the next day which was conducted once a week for 8 weeks.Electromyography(EMG)of the regional myofascial injured point was monitored and recorded using an EMG recorder via electrodes.It was considered success of the model if spontaneous electrical activities appeared in the injured site.After a 4 weeks' recovery,rats of the needling group were treated by filiform needle stimulation(lifting-thrusting-rotating)of the central part of the injured gastrocnemius belly(about 10 mm deep)for 6 min,and those of the stretching group treated by holding the rat's limb to make the hip and knee joints to an angle of about 180°,and the ankle-joint about 90°for 1 min every time,3 times altogether(with an interval of 1 min between every 2 times).The activity of the trigger point was estimated by the sample entropy of the EMG signal sequence in reference to Richman's and Moorman's methods to estimate the curative effect of both needling and exercise.Results After the modeling cycle,the mean sample entropies of EMG signals was significantly decreased in the model groups(needling group[0.034±0.010],stretching group[0.045±0.023],needling plus stretching group[0.047±0.034])relevant to the blank control group(0.985±0.196,P<0.01).After the treatment,the mean sample entropy of EMG signals was evidently increased in both needling(0.819±0.088),stretching(0.532±0.25)and needling plus stretching(0.810±0.117)groups(P<0.01).The mean sample entropy of the needling and needling plus stretching groups were significantly higher than that of the stretching group(P<0.01),without remarkable difference between the two needling groups in the mean sample entropy(P>0.05),suggesting a better efficacy of dry needling in easing trigger point activity.Conclusion Dry needling is able to relieve myofascial trigger point activity in rats,which is better than that of simple passive stretching therapy.关键词：Trigger point;Dry needling;Electromyography signal;Sample entropy;Passive stretching exercise656|373|4更新时间：2023-08-11
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