最新刊期
卷 45 ， 期 12 ， 2020
- 摘要：Scalp acupuncture is widely used in clinical practice, and there is still a lack of systematic studies on its nerve pathways and mechanism of action. Scalp acupoints are innervated by the trigeminal nerve which is also involved in the regulation of the leptomeninges and related arterioles nourishing the cerebral cortex. Animal experiments and human trials have shown that scalp acupuncture can exert an effect through the shortcut between the axon reflexes from the primary neurons in the trigeminal ganglion(its axon branches may separately innervate scalp acupoints and the leptomeninges directly regulating nutrient and active substances in brain tissue) and the secondary neurons of the trigeminal nucleus caudalis(head and face acupoints interact with afferents of brain tissue through presynaptic dorsal root reflex and postsynaptic neurogenic responses and convergence), which may have regulatory and therapeutic effects on intracranial tissue.关键词：Scalp acupuncture;Trigeminal nerve;Trigeminal nucleus caudalis;Migraine51|1132|7更新时间：2023-08-10
- 摘要：Objective To observe the effect of crossing nape electroacupuncture(EA) on cough count(CCnt), cough incubation period and blood routine, liver function, renal function, myocardial enzymology, and heart, liver and kidney pathological structure in guinea pig with cough reflex disorder after cerebral hemorrhage, so as to evaluate the efficacy and safety of crossing nape EA in the treatment of cough reflex disorder after cerebral hemorrhage. Methods A total of 160 male pure white guinea pigs were randomly divided into normal group, model group, acupuncture group, crossing nape EA group and nape EA group(n=32 in each group). These 5 groups were further divided into 1, 3, 7 and 14 d subgroups(n=8 in each subgroup). The model of cough reflex disorder after cerebral hemorrhage was established by injection of the guinea pigs' autoblood(50 μL) into the basal ganglia region confirmed by Longa's neurologic examination grading system(0—4 points). Acupuncture was applied to bilateral "Fengchi"(GB20) and "Yifeng"(SJ17) in the acupuncture group. In the crossing nape EA group, the positive pole of the needle is connected to SJ17, while the negative pole is connected to the opposite side of GB20(2 Hz, 0.5 mA). In the nape EA group, the positive pole of the needle is connected to SJ17, while the negative pole is connected to the same side of GB20(2 Hz, 0.5 mA). All treatments were applied 20 min each time, once a day. The changes of CCnt and cough incubation period were recorded by Buxco device. The changes of blood routine, liver function, kidney function, myocardial enzyme and other laboratory indexes were monitored by automatic analyzer instrument. The pathological changes of heart, liver and kidney of guinea pigs were observed by transmission electron microscopy. Results Compared with the normal group, the guinea pigs' neurological deficit scores in the model group were significantly increased at each time point(P<0.01). Compared with the model group, the neurological deficit scores of the acupuncture group, crossing nape EA group and nape EA group at 3 d, 7 d and 14 d all decreased(P<0.01, P<0.05). Following modeling, the CCnt at each time point in the model group was significantly reduced(P<0.01), and the cough latency was significantly prolonged(P<0.01). After interventions, the CCnts were increased and the incubation periods of cough were shortened(P<0.05, P<0.01) at 7 d and 14 d in the 3 intervention groups, and were superior in the crossing nape EA group than those of acupuncture group and nape EA group(P<0.05, P<0.01). The improvement degrees of these 2 indexes in the nape EA group at 14 d were better than those of the acupuncture group(P<0.05). There were no significant differences among the 3 groups in red blood cells counting, hemoglobin, myocardial enzymes, liver and kidney function(P>0.05). Compared with the normal group, the WBC counts in all the time points(except 1 d after operation) were significantly increased(P<0.01) in the model group. In comparison with the model group, the WBC counts at 3 d in crossing nape EA group, and at 7 d and 14 d in the 3 intervention groups decreased(P<0.01, P<0.05). Meanwhile, the WBC counts were lower in the crossing nape EA group at 7 d and 14 d than those of acupuncture group and nape EA group(P<0.05). The results of transmission electron microscopy showed that the histopathological structure of heart, liver and kidney of guinea pigs in each group had no significant changes. Conclusion Crossing nape EA is safe and effective in the treatment of cough reflex disorder after cerebral hemorrhage in guinea pigs. In addition, guinea pigs will have an inflammatory response after cerebral hemorrhage, and crossing nape EA may have a certain anti-inflammatory effect.关键词：Crossing nape electroacupuncture;Cerebral hemorrhage;Cough reflex;Safety43|370|1更新时间：2023-08-10
- 摘要：Objective To observe the effect of electroacupuncture(EA) preconditioning on cell apoptosis and the content of mitochondrial reactive oxygen species(ROS) in rats with myocardial ischemia/reperfusion injury(MIRI), so as to explore their mechanisms underlying improvement of MIRI. Methods Eighty male Wistar rats were randomly divided into control, sham, ischemia reperfusion(IR) and EA groups, with 20 rats in each group. Rats of the control, sham and IR groups were just banded on the boards for 30 min, once daily for 7 days. Before modeling, EA(2 Hz, 1 mA) was applied to "Neiguan"(PC6), "Zusanli"(ST36), "Guanyuan"(CV4) for 20 min, once daily for 7 successive days in the EA group. The MIRI model was established by occlusion of the left anterior descending branch of the left coronary artery for 20 min, followed by reperfusion for 30 min. Ventricular arrhythmia(VA) score was used to evaluate arrhythmia. Enzyme-linked immunosorbent assay(ELISA) was used to detect the level of CK-MB. DHE staining was used to detect the content of reactive oxygen species(ROS). The gene expression levels of cytochrome C(Cyt-C), Caspase-9 and Caspase-3 were detected by real-time fluorescent quantitative PCR. Results Compared with the sham group, VA score, serum CK-MB content, ROS content in heart tissue and Cyt-C, Caspase-9 and Caspase-3 gene expression were significantly up-regulated in the MIRI group(all P<0.01). Following the intervention, the increased VA score, serum CK-MB content, ROS content in heart tissue, Cyt-C, Caspase-9 and Caspase-3 gene expression were all reversed in the EA group compared with the MIRI group(all P<0.01). Conclusion The protective effect of EA preconditioning on MIRI may be based on the regulation of ROS mediated-apoptosis pathway.关键词：Myocardial ischemia-reperfusion injury;Electroacupuncture preconditioning;Creatine kinase MB;Reactive oxygen species;Cytochrome C;Caspase-9;Caspase-349|876|3更新时间：2023-08-10
- 摘要：Objective To observe the effect of electroacupuncture(EA) on motor function, calpain and calpastatin expression in rats with spinal cord injury, so as to explore the mechanism of EA underlying improvement of acute spinal cord injury. Methods Thirty male SD rats were randomly divided into sham operation group, model group and EA group, with 10 rats in each group. The acute moderate spinal cord injury model was established by using a NYU spinal cord impactor. EA was applied to "Jizhong"(GV6) and "Mingmen"(GV4) for 30 min, once daily for 28 d. The Basso, Beattie and Bresnahan(BBB) rating scale(0 to 21 points) was used to assess changes of locomotor function. Histopathological changes of the injured spinal cord were observed after sectioning and Nissl staining, and the expression levels of calpain1, calpain2 and calpastatin mRNA and protein in the spinal cord tissues were detected by using quantitative real-time PCR and Western blot, respectively. Results The BBB score of the model group was significantly lower than that of the sham operation group(P<0.01), and was significantly higher in the EA group than that of the model group on 14(th) and 28(th) and 28(th) day(P<0.01). Compared with the sham operation group, the number of neurons in the model group decreased, and Nissl body stained cells decreased or even disappeared, which was evidently milder in the EA group. Compared with the sham operation group, the expression levels of calpain1 mRNA and protein in the spinal cord of the model group were significantly increased(P<0.01), while the expression levels of calpastatin mRNA and protein were significantly reduced(P<0.01). Following EA intervention, in contrast to the model group, the expression levels of calpain1 mRNA and protein in the EA group were significant down-regulated(P<0.01), calpastatin mRNA and protein expression levels were significantly up-regulated(P<0.01). There was no significant difference in calpain2 mRNA and protein expression among the 3 groups(P>0.05). Conclusion EA can improve the locomotor function of rats with spinal cord injury, which may be related to its effect in inhibiting the activity of calpain in the injured spinal cord.关键词：Spinal cord injury;Electroacupuncture;Calpain;Calpastatin39|278|1更新时间：2023-08-10
- 摘要：Objective To observe the effect of electroacupuncture(EA) on proangiogenesis process and protein turn-over in a mouse model of sarcopenia, so as to explore its potential molecular mechanism anti-aging. Methods Fourteen 30-week-old male SAMP8 mice were randomly divided into a model group(n=7) and an EA group(n=7). Seven anti-rapidly aging SAMR1 mice of the same age were used as the control group(n=7). EA(1 mA, 4 Hz) was applied to bilateral "Zusanli"(ST36) and "Yanglingquan"(GB34) for 20 minutes each time once a day, 6 times a week for 4 weeks. The exhausted running platform was used to test the sports function. Gastrocnemius muscle mass and relative ratio of gastrocnemius muscle mass to body mass were measured. HE staining and transmission electron microscope were used to observe the morphology, and the cross-sectional area of gastrocnemius muscle was calculated. Relative protein expressions of protein kinase B(AKT), phosphorylated(p)-AKT, mammalian target of rapamycin(mTOR), p-mTOR, p70 ribosomal protein S6 kinase(p70 S6 K), p-p70 S6 K,hypoxia inducible factor-1α(HIF-1α) and relative mRNA expressions of HIF-1α, vascular endothelial growth factor A(VEGF-A), muscle RING finger-1(MuRF-1) and muscle atrophy F-box(MAFbx) were detected by Western blot and real-time fluorescence quantitative PCR, seperatively. Results Compared with the control group, the running time and distance, body mass and gastrocnemius mass, and the ratio of gastrocnemius mass to body mass decreased(P<0.01, P<0.05), cross-sectional area of gastrocnemius, related protein expression of p-AKT,p-mTOR, p-p70 S6 K and HIF-1α, mRNA expression of HIF-1α and VEGF-A decreased(P<0.01), while mRNA expression of MuRF1 and MAFbx increased(P<0.01) in the model group. Following EA intervention, the running time and distance, body mass and gastrocnemius mass and the ratio of gastrocnemius mass to body mass increased(P<0.05), cross-sectional area of gastrocnemius, related protein expression of p-AKT,p-mTOR, p-p70 S6 K and HIF-1α, mRNA expression of HIF-1α and VEGF-A were significantly up-regulated(P<0.01), mRNA expression of MuRF1 and MAFbx down-regulated(P<0.01, P<0.05) in the EA group compared with the model group. Conclusion EA may delay the aging muscle atrophy in mice by regulating the gastrocnemius muscle's proangiogenesis process and protein turnover.关键词：Sarcopenia;Electroacupuncture;Hypoxia;Angiogenesis;Protein turnover50|418|2更新时间：2023-08-10
- 摘要：Objective To observe the effect of moxibustion at "acupoint-open on-time"(Linggui Bafa) on immune function and nuclear factor-κB(NF-κB) signaling pathway in aging rats, so as to reveal its underlying mechanism of anti-agingt. Methods Forty SD rats were randomly divided into control, model, "Linggui Bafa" and "Shenque(CV8)" groups(n=10 in each group). Aging model was established by intraperitoneal injection of D-galactose(300 mg/kg) for 42 days. Moxibustion was applied at "acupoint-open on-time" or CV8 once daily for 28 days. The serum levels of TNF-α, IgG, IgA and IgM were detected by ELISA. The spleen index of rats was calculated. The expression of NF-κB p65 and NF-κB inhibitor protein(IκB) α mRNA of spleen tissues was detected by real-time PCR. Results Compared with the control group, the expression level of serum TNF-α, the mRNA expression levels of NF-κB p65 and IκBα in the model group was significantly increased(P<0.01), while the expression levels of serum IgG, IgA and IgM, and the spleen index in the model group were significantly decreased(P<0.01). After the treatment, mode-ling-induced increase of serum TNF-α, NF-κB p65 and IκBα mRNA expression levels and decrease of serum IgG, IgA, IgM levels, the spleen index were all completely reversed in the two treatment groups relevant to the model group(P<0.01, P<0.05). No significant change was found in the above-mentioned indexes between the two treatment groups(P>0.05). Conclusion Moxibustion at both "acupoint-open on-time" and CV8 can enhance the immune function of aging rats, which may be related to its effects in inhibiting NF-κB signaling pathway.关键词：Linggui Bafa;Aging;Immune function;NF-κB signaling pathway41|371|3更新时间：2023-08-10
- 摘要：Objective To investigate the clinical change of post-stroke dysphagia after the intervention of Liyan Tongqiao(relieving sore-throat and dredging orifices)acupuncture using cranial diffusion tensor imaging(DTI). Methods A total of 60 patients with post-stroke dysphagia were enrolled and randomly divided into Liyan Tongqiao acupuncture group and neurology treatment group, with 30 patients in each group. The patients in the neurology treatment group were given routine neurology treatment and swallowing rehabilitation training, and those in the Liyan Tongqiao acupuncture group received acupuncture at Sishencong(EX-HN1), Baihui(GV20), bilateral Tai-yang(EX-HN5), and bilateral Fengchi(GB20) and tongue triple acupuncture, with an electroacupuncture apparatus for EX-HN1, bilateral GB20, and tongue triple acupuncture, for a needle retaining time of 30 minutes each time, once a day and 5 times a week, in addition to the treatment in the neurology treatment group. Each course of treatment was 3 weeks, and both groups were treated for 2 courses. Swallowing function assessment and cranial DTI were performed after treatment. Results After 6 weeks of treatment, both groups had a marked improvement in swallowing function, a significantly greater change in video fluoroscopic swallowing study(VFSS) score and a higher mean FA value(P<0.05). Compared with the neurology treatment group, the Liyan Tongqiao acupuncture group had a marked improvement in swallowing function, a significantly greater change in VFSS score in the pharyngeal phase and a higher mean FA value(P<0.05). Conclusion Liyan Tongqiao acupuncture can improve dysphagia and swallowing function in the pharyngeal phase in VFSS, possibly by promoting the remodeling of cerebral cortex and increasing the FA value of infarct zone through the stimulation of related acupoint signals.关键词：Liyan Tongqiao acupuncture treatment;Dysphagia;Diffusion tensor imaging39|494|1更新时间：2023-08-10
- 摘要：Objective To observe the effect of round magnetic needle tapping along meridians on the back plus acupuncture at "Qi Shen Zhen"(including Shenting [GV24], Benshen [GB13], Sishenchong [EX-HN1]), and Baihui(GV20), Shenmen(HT7) on gastrointestinal function, daily living activities and anxiety status in post-stroke anxiety disorder(PSAD) patients. Methods Fifty-seven PSAD patients were randomly divided into acupuncture group(28 cases) and medication group(29 cases). On the basis of routine treatment and physical therapy, patients of the acupuncture group were treated by applying round magnetic needle to mildly tapping the second line→the first line of the Bladder Meridian→Jiaji acupoints→Governor Meridian on the back from outside to the inside in sequence for 20 min, followed by needling GV24, GV20, GB13, EX-HN1 and HT7, respectively, with the needles retained for 30 min after one minute's twisting. The treatment was conducted once daily, 5 times a week, for 6 weeks. Patients of the medication group were asked to take Escitalopram Oxalate tablets(5—20 mg/d) for 6 weeks. The Hamilton Anxiety Rating Scale(HAMA) was used to assess the patient's severity of anxiety, cognition, somatic sensation, symptoms of cardiovascular, respiratory, gastrointestinal, urogenital, automatic and muscular systems, the Barthel Index(BI) used to evaluated the activities of daily living(ADL), and the gastrointestinal function(Spleen-stomach Symptom Score [SSS]) assessed according to the "Standards for Diagnosis and Curative Effect Evaluation of Syndromes of Traditional Chinese Medicine". The adverse reactions were observed at the end of treatment. Results After the treatment, the HAMA scores at the 2(nd), 4(nd), 4(th) and 6(th) and 6(th) week and the SSS scores at the 4(th) week and the SSS scores at the 4(th) and 6(th) and 6(th) week were significantly decreased(P<0.05), and the BI scores at the 2(th) week were significantly decreased(P<0.05), and the BI scores at the 2(nd), 4(nd), 4(th) and 6(th) and 6(th) week were considerably increased in both acupuncture and medication groups compared with their own pre-treatment(P<0.05). The HAMA score at the 2(th) week were considerably increased in both acupuncture and medication groups compared with their own pre-treatment(P<0.05). The HAMA score at the 2(nd) week, and the SSS scores at the 2(nd) week, and the SSS scores at the 2(nd), 4(nd), 4(th) and 6(th) and 6(th) week were obviously lower(P<0.05), and the BI score at the 6(th) week were obviously lower(P<0.05), and the BI score at the 6(th) week was notably higher in the acupuncture group than in the medication group(P<0.05). No significant diffe-rence was found between the two groups in the therapeutic effect of anxiety state(P>0.05). The acupuncture group had fewer adverse reactions than the medication group(P<0.05).Conclusion The round magnetic needle tapping plus "Qi Shen Zhen" needling has a significant therapeutic effect in improving PSAD patients' anxiety state, being similar to Escitalopram Oxalate tablets in reducing anxiety state and being superior to Escitalopram in improving gastrointestinal function and daily living activities.关键词：Post-stroke anxiety disorder;Tapping along meridians;"Qi Shen Zhen" needling;Anxiety;Gastrointestinal function;Daily living ability37|347|1更新时间：2023-08-10
- 摘要：Objective To observe the clinical effect of acupuncture on patients with stroke-related headache during convalescent and analyze its related factors. Methods A total of 116 stroke-related headache patients admitted to the Acupuncture Department of Gongli Hospital of Pudong New Area, Shanghai, from October 2018 to December 2019 were divided into a treatment group and a control group according to a random number table, with 58 cases in each group. Patients in both groups were given conventional treatments for control of blood pressure, blood sugar, blood lipids and anticoagulation. At the same time, patients in the treatment group were treated with "nape seven needles"(acupuncture at Fengfu[GV16], bilateral Fengchi[GB20], bilateral Tianzhu[BL10] and bilateral Wangu[GB12])combined with penetration needling for 30 min; patients in the control group were treated with Flunarizine hydrochloride capsules(5 mg). Both interventions were conducted once daily for 4 weeks. The visual analogue scale(VAS) score and integrative sores of headache, and plasma serotonin(5-HT), dopamine(DA), substance P(SP), α-endorphin(α-EP), and β-endorphin(β-EP) levels before and after treatment were compared between the two groups. The total therapeutic effective rate of the two groups was calculated. Results There was no significant difference in VAS score, headache score, plasma 5-HT, DA, SP, α-EP, β-EP levels between the two groups before treatment(P>0.05). After treatment, both groups have significant decrease in the VAS score, integrative sores of headache, the plasma 5-HT, DA, SP levels(P<0.05), and significant increase in the plasma α-EP and β-EP levels(P<0.05). At the same time, the VAS score, integrative sores of headache, the plasma 5-HT, DA, SP levels of the treatment group were lower(P<0.05), and the plasma α-EP and β-EP levels were higher(P<0.05) than those in the control group. The total effective rate of the treatment group(51/58, 87.9%) was higher than that of the control group(42/58, 72.4%, P<0.05).Conclusion Acupuncture therapy can increase the release of endogenous opioid peptide, reduce the secretion of 5-HT, DA, SP, and have a significant effect in treating stroke related headache.关键词：Acupuncture;Ischemic stroke;Headache;Endogenous opioid peptides45|372|0更新时间：2023-08-10
- 摘要：Objective To observe the therapeutic effect of "Tiaoyi Sanjiao"(regulating and tonifying the triple energizer)acupuncture and moxibustion in the treatment of cancer-related fatigue of advanced non-small cell lung cancer and observe its influence on lymphocyte count. Methods The cancer-related fatigue patients with advanced non-small cell lung cancer who met the inclusive criteria were randomly divided into 2 groups, with 77 cases in each group. Patients in the control group were treated with conventional Chinese and Western medicine. In the treatment group, on the base of the treatment as the control group, "Tiaoyi Sanjiao" acupuncture and moxibustion was applied(mild moxibustion at Danzhong [CV17], Zhongwan[CV12], Qihai[CV6], bilateral Zusanli[ST36], and acupuncture at bilateral Xuehai[SP10], Waiguan[SJ5], Taichong[LR3]). KPS score, Piper scale, percentage and absolute count of lymphocyte subsets of the two groups before and after treatment were observed. Results Compared with pre-treatment, the KPS scores of both groups were significantly increased after treatment(P<0.05); the behavioral dimension score of the Piper scale, and the percentage of B cells of the control group decreased significantly(P<0.05); the behavioral dimension, emotional dimension, sensory dimension scores, and total score of the Piper scale in the treatment group were significantly reduced(P<0.05), while the percentage of CD3+T cells and absolute counts of CD3+T cells and absolute counts of CD3+T cells, CD4+T cells, CD4+T cells and CD8+T cells and CD8+T cells of the treatment group were significantly increased(P<0.05). After treatment, in comparison with the control group, behavioral dimension score of the Piper scale in the treatment group decreased significantly(P<0.05); the percentage and absolute counts of B cells and CD4+T cells of the treatment group were significantly increased(P<0.05). After treatment, in comparison with the control group, behavioral dimension score of the Piper scale in the treatment group decreased significantly(P<0.05); the percentage and absolute counts of B cells and CD4+T cells, the absolute count of CD3+T cells, the absolute count of CD3+T cells in the treatment group were up-regulated(P<0.05). Conclusion "Tiaoyi Sanjiao" acupuncture and moxibustion can significantly alleviate the fatigue state and improve the quality of life in patients with advanced non-small cell lung cancer, which may be achieved by regulating the number of lymphocytes and improving immune function.关键词：Tiaoyi Sanjiao acupuncture and moxibustion;Cancer-related fatigue;Advanced non-small cell lung cancer;Lymphocyte subsets;Absolute count43|816|2更新时间：2023-08-10
- 摘要：Objective To investigate the anesthetic effect of combined acupuncture-medicine anesthesia in microwave ablation of benign thyroid nodules and its effect on serum β-endorphin. Methods A total of 60 patients who met the inclusion criteria and received microwave ablation of benign thyroid nodules were randomly divided into the treatment group and the control group, with 30 patients in each. The patients in the treatment group were given combined acupuncture-medicine anesthesia, and those in the control group were given intravenous anesthesia. The two groups were compared in terms of the sedative and analgesic effects of anesthesia, amount of anesthetics used, incidence rate of intraoperative snore and respiratory depression, and change in serum β-endorphin level before anesthesia, before surgery, and after the surgery. Results Both groups obtained satisfactory anesthetic effects. Compared with the control group, the sedation score, the amounts of fentanyl and propofol used, the incidence rates of intraoperative snore and respiratory depression in the treatment group were obviously lower(P<0.05, P<0.01). The treatment group had an increase in serum β-endorphin level before surgery and at the end of surgery(P<0.05), while the control group showed no significant change in serum β-endorphin level at each time point. Conclusion In microwave ablation of benign thyroid nodules, combined acupuncture-medicine anesthesia has good sedative and analgesic effects and can reduce the amounts of anesthetics used as well as the incidence rates of intraoperative snore and respiratory depression. The analgesic effect of acupuncture anesthesia is associated with increased β-endorphin secretion.关键词：Combined acupuncture-medicine anesthesia;Thyroid nodule;Microwave ablation;β-endorphin30|323|2更新时间：2023-08-10
- 摘要：Objective To observe the effects of auricular magnetic bead pressing on maternal body temperature, inflammatory response and placental pathological results in epidural labor analgesia. Methods 180 parturient who volunteered for labor analgesia were randomly divided into epidural group(n=90, epidural labor analgesia) and auricular pressing group(n=90, epidural labor analgesia combined auricular pressing). The tympanic temperature before labor analgesia(T1), 2 h(T2), 4 h(T3) and 4 h after labor analgesia(T4) were recorded. The total duration of labor, duration of labor analgesia, PCEA compression times, labor analgesia dose, cesarean section rate was counted, and the changes in serum IL-6 level and placental pathology results of the two groups were analyzed. Results There was no significant difference in age, BMI, gestational age, duration of labor, duration of analgesia and rate of cesarean section between groups(P>0.05). Times of PCEA compressions and labor analgesic dose in auricular group were lower than that in epidural group(P<0.05). There was no difference in tympanic temperature between two groups at T1(P>0.05), and the tympanic temperature at T3 and T4 was higher than that at T1(P<0.05). The tympanic temperature in T3 and T4, and incidence of intrapartum fever in the auricular group was lower than that in the epidural group(P<0.05).There was no difference in the prenatal serum IL-6 level between groups(P>0.05), and the postpartum serum IL-6 level was higher than that before labor in either group(P<0.05).The postpartum serum IL-6 level and the incidence of HCA in the auricular point group were lower than those in epidural group(P<0.05). Conclusion Magnetic beads auricular pressing therapy has advantages in reducing intrapartum fever by modulating maternal inflammation and reducing the dosage of local anesthetics effectively during epidural labor analgesia.关键词：Auricular pressing therapy;Labor analgesia;intrapartum Fever;Inflammation factor;Chorioamnionitis46|311|0更新时间：2023-08-10
- 摘要：Objective To observe the clinical efficacy of long snake moxibustion and Ashi-point moxibustion in the treatment of cold-dampness type chronic non-specific low back pain(CNLBP) patients. Methods A total of 120 cold-dampness type CNLBP patients who signed the informed consent were randomly and equally divided into control, long snake moxibustion and Ashi-point moxibustion groups. Ginger-separated moxibustion was applied to the region between Dazhui(GV14) and Yaoshu(GV2) for patients of the long-snake moxibustion group, or to the tenderness spot of the waist for patients of the Ashi-point moxibustion group. The treatment was conducted for 40 min each time, once every other day for a total of 8 sessions. Patients of the control group did not receive any intervention. The visual analogue scale(VAS) was used to assess low back pain severity. The Oswestry Disability Index(ODI) was employed to assess ten aspects of patients' daily-life activities(pain intensity, personal care, lif-ting, walking, sitting, standing, sleeping, sex life, social life, and traveling). The cold-damp syndrome scores(pain property, symptoms, ranges of motion, waist palpation, tongue and pulse condition) were achieved by consulting the textbook "Differential Diagnostics of Traditional Chinese Medicine Syndromes". The Hospital Anxiety and Depression Scale(HADS, a self-made assessment instrument) was used to assess the patients' severity of emotional disorder. The plasma cortisol level was detected by ELISA. Results Before treatment, there were no significant differences among the three groups in the levels of all the indexes(P>0.05). After moxibustion, the VAS scores during rest and movement, ODI score, cold-damp syndrome score and anxiety score in both long snake moxibustion and Ashi-point moxibustion groups, and the HADS depression score and plasma cortisol content in the long snake moxibustion group were significantly reduced compared with their own pre-treatment(P<0.05). The difference values between pre and post-treatment of VAS scores during rest and movement, ODI score, cold-damp syndrome score, anxiety score, depression score and cortisol content were obviously higher in the long snake moxibustion and Ashi-point moxibustion groups than those in the control group. The difference values between pre-and post-treatment of VAS scores during rest and movement, ODI score, cold-damp syndrome score, anxiety score, depression score and cortisol content were obviously higher in the long snake moxibustion group than in the Ashi-point group(P<0.05). Conclusion Both ginger-separated long snake moxibustion and Ashi-point moxibustion can relieve low back pain, daily-life activities, cold-damp syndrome, negative emotions, and reducing cortisol level in cold-dampness type CNLBP patients,and the therapeutic efficacy of long snake moxibustion is obviously better.关键词：Long-snake moxibustion therapy;Chronic non-specific low back pain(CNLBP);Negative emotions;Plasma cortisol41|715|1更新时间：2023-08-10
- 摘要：In recent years, a new technique of elastic quantization imaging, the ultrasound-based shear wave elastography(SWE) is arising, which has advantages of real-time, non-invasion, rapid imaging and strong repeatability, and quantifying the elastic properties of soft tissues including thyroid gland, breast, prostate, muscle tendon, ligament, etc.. It has been gradually applied to clinical and experimental researches of acupuncture and has an extensive application prospect. The present paper briefly introduces the application of SWE in accurately locating the acupoint, Deqi from needled acupoints, acupuncture manipulations, and evaluation of efficacy of acupuncture in the treatment of musculofascial diseases.关键词：Shear wave elastography;Deqi;Acupuncture manipulation;Effect evaluation42|463|2更新时间：2023-08-10
- 摘要：Through collecting the relative records about "Nishun"(contradiction and consistency between pulse conditions and severity of illness) in pulse taking for acupuncture treatment in ancient literature of traditional Chinese medicine, and combining with the understanding about pulse taking in Lingshujing(Miraculous Pivot) and later generations' clinical application, the different meanings of "Nishun" are analyzed in the present article. It is concluded that pulse taking during acupuncture treatment is considered the fundamental principle in the age of Lingshujing, and if the pulse conditions are contradicted to the illness, acupuncture treatment is prohibited. The practitioners of the later generations also emphasized that only by ensuring no contradiction between the pulse conditions and illness, could we operate acupuncture treatment. These greatly expand the contents of "Nishun" when taking pulse conditions for acupuncture treatment. All of these have a positive significance to the further research on pulse taking for acupuncture treatment.关键词：Ancient literature;Lingshujing(Miraculous Pivot);Pulse taking for acupuncture treatment;Contradiction or consistency between pulse conditions and illness34|339|0更新时间：2023-08-10
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