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Online ISSN: 2097-7042

Print ISSN: 1000-0607

CN: 11-2274/R

Governing Body: National Administration of Traditional Chinese Medicine

Sponsors: Institute of Acupuncture and Moxibustion, CACMS; China Association of Acupuncture-Moxibustion

Publishing Frequency: Monthly

Tel: +86-10-64089344

Email: zcyjbjb@vip.163.com

Address: 16 Nanxiaojie, Dongzhimennei, Beijing, China

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Volume 51 期 9，2026 2026年第51卷第9期

    Han Jisheng, Jiang Haiting

    DOI：10.13702/j.1000-0607.20260816
    摘要：On the occasion of the 50th anniversary of the founding of Acupuncture Research， this paper systematically reviews the milestone value of the journal in promoting the scientification， standardization， and internationalization of acupuncture-moxibustion medicine. Integrating the core research achievements of the authors’ team over the past sixty-odd years—particularly the classic literature published in Acupuncture Research over the last half-century—this article deeply analyzes the development characteristics of modern acupuncture research in its transition from “empirical verification” to “mechanism-driven” science. Furthermore， it elucidates four core pathways for the high-quality development of the acupuncture research field： first， emphasizing the neurochemical principles of acupuncture analgesia to drive theoretical and technological innovation through heritage preservation； second， harnessing translational medicine as a developmental catalyst to integrate basic medicine and clinical medicine； third， spearheading the evolution of the “Clinical+X” paradigm via brain-computer interfaces； and fourth， prioritizing the standardization and internationalization of acupuncture research， while strengthening the building of multidisciplinary talent teams to enhance China’s voice and leadership in the field of global acupuncture governance. Ultimately， this work provides a robust theoretical foundation and forward-looking horizons for constructing a modern acupuncture medical system with Chinese characteristics and advancing the cause of global health.  
    关键词：Acupuncture research;Translational medicine;Brain-computer interface;Standardization;Talent cultivation;Clinical + X   
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    更新时间：2026-09-21

    Zhu Bing

    DOI：10.13702/j.1000-0607.20260786
    摘要：This paper systematically elaborates the theories of stress， biological resilience and hormesis. Mild low-dose stress induces organismic overcompensation via preconditioning， activates nuclear factor erythroid 2-related factor 2 （Nrf2）-mediated antioxidant， autophagy， DNA repair and other pathways， and presents an inverted U-shaped biphasic dose-response relationship. Preconditioning is categorized into local and remote types， which exerts long-term protective effects on systemic organs via metabolic reprogramming as well as neuro-humoral and immune pathways， with 2 distinct protective time windows （early and delayed）. Numerous clinical trials have validated that remote ischemic preconditioning improves the prognosis of organ transplantation， stroke， hypertension and other diseases， yet its clinical application is limited by the requirement to predict injuries in advance. It proposes that somatic stimulation therapies including acupuncture， scraping and cupping act as mild stress-like interventions that fully conform to the six core characteristics of hormesis. By regulating oxidative stress， inflammatory response， mitochondrial function and DNA repair pathways， these therapies elevate systemic biological resilience， consistent with the evolutionary law that “mild stress confers benefits” and the traditional Chinese medicine health-preserving philosophy of tempering vitality through hardship as recorded in ancient texts. Acupuncture can be applied to perioperative care， chronic disorders， neurological diseases and full-life-cycle health management. Nevertheless， current research on acupuncture modulating resilience-related pathways remains insufficient， and in-depth exploration of its underlying basic mechanisms and clinical translation is still warranted.  
    关键词：Biological resilience;Hormesis;Preconditioning;Acupuncture;Nrf2 pathway   
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    更新时间：2026-09-21

    罗勇

    DOI：10.13702/j.1000-0607.20260819
      
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    更新时间：2026-09-21

    吴根诚

    DOI：10.13702/j.1000-0607.20260818
      
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  • Special Issues
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Special Issue on Innovative Exploration and Interpretation of Acupuncture Neural Circuits

Special Issue on Innovative Exploration and Interpretation of Acupuncture Neural Circuits

key scientific questions in acupuncture and moxibustion support the development of modern acupuncture medicine

key scientific questions in acupuncture and moxibustion support the development of modern acupuncture medicine

Special lssue on Acupuncture-moxibustion and Tumor

Special lssue on Acupuncture-moxibustion and Tumor

Special lssue on Acupuncture-moxibustion and Translational Medicine

Special lssue on Acupuncture-moxibustion and Translational Medicine

Special lssue on Acupuncture-moxibustion and Chronic Inflammatory Diseases

Special lssue on Acupuncture-moxibustion and Chronic Inflammatory Diseases

Special Issue on Interdisciplinary and Acupuncture Development

Special Issue on Interdisciplinary and Acupuncture Development

Column of the Institution 70th Anniversary

Column of the Institution 70th Anniversary

Column on Acupuncture Analgesia

Column on Acupuncture Analgesia

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Journal videos

  • Interpretation of the Cover of Acupuncture Research Issue 8, 2026 00:00:00

    Interpretation of the Cover of Acupuncture Research Issue 8, 2026

    2026-08-17
    播放量： 20
  • Interpretation of the Cover of Acupuncture Research Issue 6, 2026 00:01:21

    Interpretation of the Cover of Acupuncture Research Issue 6, 2026

    2026-06-15
    播放量： 18
  • Interpretation of the Cover of Acupuncture Research Issue 5, 2026 00:01:33

    Interpretation of the Cover of Acupuncture Research Issue 5, 2026

    2026-05-18
    播放量： 10
  • Interpretation of the Cover of Acupuncture Research Issue 3, 2026 00:01:18

    Interpretation of the Cover of Acupuncture Research Issue 3, 2026

    2026-04-21
    播放量： 7
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