最新刊期
卷 ， 期 3 ， 1985
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- 摘要：One handred and nineteen cases of hemiplegia suffering from cerebro- vascular accidents were treated with neeclling at the cervical sympathetic nerve trunk (CSNT). The procedure of treatment was: the patient lay flat in supine-position, both sides of neck were exposed and cleaned with 75% alcohol. The carotid arteries were pushed laterally, an acupu- ncture needle, size 24-26, was inserted at a point between the lateral bor- der of the thyroid cartilage and the carotid artery, one on each side. The needles were inserted perpendicularly about 3-4 cm. in depth, retained for 10-15 minutes and rotated for 2-3 times during needling. If the pro- cedure was correctly done, the patient would feel a sense of soreness and distention radiating along the neck to shoulders and arms. The needling was performed once daily for 10 times as a course of therapy, and 2-5 co- urses migth be needed according to the patient's response. As for compa- rison, two similar but much smaller groups of patients were treated, eitrer with conventional acupuncture for hemiplegia (10 cases)or with traditional Chinese and western medicine (22 cases) on patients requisition at the same period. The result of treatment was as following: of 119cases treated with CSNT needling; 3 showed rapid and complete recovery, 10 showed marked improvement, 88 cases had substantial improvement and 18 cases failed to response. The total effective rate was 84.9%. CSNTneedling was espe- cially useful for patients treated in acute or early stage of the episode as compared to patiants in late or sequelae stage (P<0.01). For the favourable responders, the myotonia, grasping power, status of walking and aphasia improved rapidly. For severely affected patients, their consciousness and orientation would improved quickly too. The improvement usually occurred within 10-20 days after begining of treatment. No complications were seen. The CSNT treated group showed a much favourable effect than the medi- cinal treated group (P<0.001). Although the CSNT treated group seemed to have better result than the conventional acupuncture group, there was no statistioal signifioance. On follow-up study, 77 patients of CSNT needling group were checked up 6 months to 2 years after ceasation of the treatment. 21 patients showed further improvement, 45 sustained their good effect, the rest reg- ressed to their pretreatment state This made a follow up effective rate of 85.75% The mechanism of its actiom was still unknowm.926|0|0更新时间：2023-08-11
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- 摘要：The effects of electroacupuncture on dorsal hippocampal pyramidal ce- lls spontaneous firing under the condition of electrical stimulation or le- sion of locus coeruleus (LC) were investigated in urethane anesthetized ra- ts. The spontaneous firing of dorsal hippocampal cells was mainly inhibi- ted when electroacupuncting ‘Jiaji’points. Similar inhibitory effects of electrical stimulatinn on LC were observed. The effects of electroacupun- cture were not appeared after lesions of bilateral LC, or partially blocke- d after iv phentolamine (an a-receptor antagonist), and completely blocke- d after yohimbine (an a_2-antagonist). Clonidine (an a_2-receptor agonist) was ineffective in this regard. These results suggest that LC may be an important links in effect of electroacupuncture on pyramidal cells firing of hippocampus. It also showed that the effect of electroacupuncture seemed to be mediated by a-receptor, especially that by a_2 receptor.1036|0|0更新时间：2023-08-11
- 摘要：We have reported in our previous studies that stimulation of the spla- nchnic nerve evoked unit discharges in thalamic PO nucleus of cat which showed the characteristics of pain discharge. The present paper further stu- died the relationship between A-fiber afferent impulse of splanchnic nerve and the evoked discharges of PO nucleus. Experments were carriedout on 11 cats immobilized witb flaxedil under artificial respiration. Unit discharges were recorded by glass microelectrode (1-2μ) from PO nucleus and the afferent impules from splanchnic nerve were monitored by recording its action potentials. 25 units were found to show evoked discharges by stimulating the spla- nchnic nerve with a strong single pulse. The latent period was 58±12.1 msec. weak stimulation of splanchnic were (only A. fibers were activated)fa- iled to evoke any discharge in PO. Activation of all A fibers (especially the Aδ fibers) by stronger sti- mulation evoked discharges in PO nucleus. Blockade of A fibers by direct current eliminated these evoked discha- rges. The spontaneous discharge of all the 25 units decreased or disappeared following the evoked discharges, and then restored or even angmented. The results indicated that Aδ activation was responsible for the evoked cluster of discharges with short latent period by afferent splanchnic nerve impu- lses. The evoked discharges were followed by an inhibitory period during which the spontaneous discharges were inhibited.875|0|0更新时间：2023-08-11
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- 摘要：The effects of substance p (sp) microiontophoretically applied on spi- nal dorsal horn neurones were observed in 32 rats. Sp caused an increas in excitability for majority of the units affected by sp and a decreas only for a few units. The examination in receptive character of 25 units showed that 20 of 25 units can be excited by noxious mechanical stimulus or/and noxious heat or/and bradykinin applied and 18 of 20 units can also be excited by micro- iontophoretic sp. But the rest which were non-nociceptive units failed to respond to sp or were slightly inhibited by sp. The results support the po- int of view that sp acts as a neurotransmitter or modulater in spinal pain pathways. The excitatory effect of 15 of 17 units caused by sp was inhibited by electro-acupuncture stimulation at Zusanli points. 4 of 5 units tested for the effect of naloxone on the electro-acupuncture action showed that the i- nhibitory action of acupuncture stimulation on excitatory effect of sp fai- led to be blocked by microiontophoretic naloxone. It is suggested that the mechanism of acupuncture analgseia in spinal cord includs postsynaptic nhi- bition and endogenous opiate-like substance may not play an important role in the inhibitory mechanism.941|0|0更新时间：2023-08-11
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- 摘要：Evidences obtained from different lines have shown that 5-hydroxytry- ptamine (5-HT) plays an important role in mediating electroacpuncture ana- lgesia (EAA). However, Cheng and Pomeranz in 1979 reported that p-chlo- rophenylalanine(pCPA), the specific inhibitor of the 5-HT synthetic enzy me, was effective in decreasing only high frequency EAA, but not the low frequency EAA in the mice. To evaluate whether this is true in the rat, we have used EA of 4 frequencies (2, 15, 100Hz fixed frequency and 2-15 Hz changing frequenecy EA stimulations) and 2 intensities (3V, 9V) to assess the effect of pCPA on EAA. The effect of EAA in control rats injected with normal saline were rather stable in a period of 2 weeks. Intraperitoneal injection of pCPA 320mg/kg) resulted in a marked decrease (-84% to-90%) of the effect of EAA 3 and 5 days after the ip injection, followed by a gradual recovery which completed in 13 days. The decrease of EAA was of similar degree whether low or high frequency, weak or strong intensity EA stimulations were used. It is thus concluded that 5-HT is important in mediating not only high frequency, but also low frequency EA analgesia in the rat.996|0|0更新时间：2023-08-11
- 摘要：The purpose of this study was to ascertain the role of the peripheral sympathetic activity on acupuncture analgesia. 50 rats which had a comparatively stable pain threshold and a more than 50% rise of pain threshold at 10 minutes after acupuncture induction were randomly divided into three groups: 1) 30mg/kg 6-OHDA + acupuncture; 2) 100mg/kg + acupuncture; 3) Saline + acupucturel All of them, 6-OHDA and same volume of saline were administered intraperitoneally 5 days before experiment respectively. "Zusanli" and "pishu" points were electroacupunctured with 20 CPS, 2-4 mA and 60 CPS 1-2 mA respectively. The analgesia effect of electro-acupuncture was estimated by using the potassium iontophoresis tail-flick test. The content of noradrenalin (NA) in brain and the change of fluorescent intensity of NA in the peripheral sympathetic nerve terminals were determined immediately after analgesia experiment. Results were summarized as follows: In 6-OHDA groups, the fluorescent intensity of NA in the peripheral sympathetic nerve terminals in organs such as gastric wall, duodenum, heart, kidney was markedly weaker than that in saline group. But the content of NA in cortex, diencephalon and brain stem was no significantly different. It suggested that only was the majority of the peripheral sympathetic nerve terminals damaged by inject- ing 6-OHDA, under this condition, the acupuncture analgesia was notably enhanced (1.15±0.047mA - 1.46±0.088 mA, p<0.01, n=12), but in saline contral group, it was no change (1.28±0.073 mA - 1.23±0.093mA, p>0.05, n=23). The results suggested that besides central mechanism of acupuncture ana- lgesia, the excitability of the peripheral sympathetic system might be an important fact in acupuncture analgesia. In our previous studies, it had been found that acupuncture analgesia was almost simultaneous with the inhibitory effect of acupuncture on the peripheral sympathetic nerve, It is assumed that acupuncture inhibits the vasocontrction fibers of sympathetic nerve which in turn influence micrci- rculation. to change the excitability of free nerve endings, Moreover, the inhibitory effect of acupuncture on sympathetic nerve could decrease 5-HT releasing into blood from APUD cells, It might improve microcirculation and benefit the analgesia.864|0|0更新时间：2023-08-11
- 摘要：Whether the generation of PSC is influenced by psychological factors of the observed subjects, it is an important problem ought to be sol ved. In this study the authors inspired the subjects by using signals of sound, li- ght and eletricity, by describing the lines of PSC with model or chart of channel, by drawing lines of PSC on the body surface of the subjects, or by giving distinct suggestions to the subjects with obvious hinting conver- sations. We have observed the PSC phenomena of the channels. In 250 first vi- sit patients the results were as follows: (1) Before strong suggestion, the rate of appearance of PSC was 2.0% in marked models, 17.6% in relative marked models and 80.4% in insensi- tive models respectively. After strong suggestion, the rate of appearance was 2.0%, 18.8% and 79.2% in corresponding models respectively. Comparisons in each corresponding models showed no significant differences in their statistical treatments (p>0.05). (2) Before and after the strong suggestion, the lengths of PSC lines of the Large Intestine Channel were 56.34±0.48cm and 57. 65±0.56 cm; the widths were 1.78±0.22cm and 1.97±0.22cm; the velocities were 9.23±0.41 cm/sec and 10.02±0.44 cm/sec respectively. The compared statistical results of three items had no significant diferences (p>0.05). Before and after the strong suggestion, the lengths of PSC of the Ga- llbladder Channel were 92.65±0.51 cm and 91.74±0.45cm, the widths were 2.53±0.31 cm and 2.25±0.29 cm, the velocities were 8.98±0.30 cm/sec and 8.62±0.28cm/sec respectively. The compared statistical results of three items had no significant differences (p>0.05). (3) When we made the PSC suggestions to directions of Spleen Channel and the Stomch Channel respctively at 18 Channel-times for the three subjects who had marked PSC along the Large Intestine Channel and the Pericardium channel, we did not found the deviations of PSC to the Spleen and Stomach Channel. These observed results show that strong suggestions have no obvious and important influences on PSC, and PSC phenomena are not the results of psychological effects or due to subjective factors, It reveals that the Channel lines are not noly related to the central nervous system, but also possess certain substantial structure on the body surface and definite physio- logical foundations.660|0|0更新时间：2023-08-11
- 摘要：From the histological and pathological reactions and electrical characteri- stic sof acupoints as well as their effects on the functions of various organs, the author in accordance with a lot of clinical and experimental materal, has demostrated that acupoints are regularly provided with relative specificity, and proposed that such a relative specificity is the foundation for the acupuncture therapy.696|0|0更新时间：2023-08-11
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