汉防己具有一定的镇痛和肌松作用。把汉防己总硷和针刺合并应用

是否是一种有利于提高针刺麻醉效果的复合措施?我们用家兔单侧电针镇痛模型

观察了汉防己总生物硷对动物电针镇痛效果的影响。实验材料及方法以体重1～2公斤的普通健康家兔为实The whole alkaloids of Radix Stephaniae Tetrandrae (dose 15mg/kg body wt.

i. v.) and the stimu-lation of unilateral acupuncture points "Shenshu" "Lianchu" raised the pain thresholds of the rabbit'sdigital webs about 30% higher than that of the control (34.4±6% and 37.3±3% respectively). The anal-gesic effect was significantly diminished

while the acupuncture was combining with an intravenousdose of the whole alkaloids. On the unpunctured side of the combination treatment cases

the pain threshold was higher than onthe punctured side. But in the cases treated with acupuncture alone

the pain thresbold was always higheron the punctured side. This reversion phenomenon and the significant diminution of pain threhold onthe punctured side of the combination treatment cases

indicate that the whole alkaloids of rad. stephaniaetetrandrae is an antagonistic in acupuncture analgesia. The mechanism underlying this antagonistic ef-fect is unknown.