在针刺作用原理研究中

人们发现针刺效应与针刺后交感神经系统机能活动的变化有较密切的关系。有的工作表明

针刺可使交感神经活动受到相对抑制;也有人报道钎刺对交感神经活动有兴奋作用。己经知道

中枢肾上腺素能机能与外周交感神经活动之间存在着复杂的关系。中枢肾上The post-ganglionic discharges from the splanchnic nerves in 48 rabbits were recorded. Arterial blood pressure was also recorded in some exper- iments. After electro-acupuncture at "Tsusanli" point the splanchnic discharges were potentiated while the inhibitory phase of costo-visceral reflex was di- minished. This showed that electro-acupuncture had an excitatory action on sympathetic activity concerned with viscera. The splanchnic discharges were potentiated after intraventricular in- jection of alpha-adrenergic antagonist phentolamine (0.5mg) or beta- adrenergic agonist isoproterenol (0.06mg). Intraventricular injection of beta-adrenergic antagonist propranolol (0.12mg) or alpha-adrenergic agonist methoxamine (1mg) induced attenuation of splanchnic discharge and the excitatory action of electroacupuncture was reduced or abolished. These results showed that the effects of electro-acupuncture on sympa- thetic activity had something to do with adrenergic receptors in central nervous system

in which the beta-adrenergic receptor presented an agon- istic effect

but alpha-adrenergic receptor exerted an antagonistic effect

on acupuncture.