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中医研究院针灸研究所
纸质出版日期:1981
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葛子, 宋万成, 王志英, 等. 电针、吗啡对脑内微循环影响的组化观察[J]. 针刺研究, 1981,(2):151-156.
Ge Zi Song Wancheng Wang Zhiying Huang Weimin. THE INFLUENCE OF ELECTRO-ACUPUNCTURE AND MORPHINE UPON THE INTRACRANIAL MICROCIRCULATION[J]. Acupuncture research, 1981, (2): 151-156.
祖国医学认为针刺的镇痛和治疗作用
在于通经脉
调气血.在针麻过程中
有人用血管反应和容积脉搏波作为针麻导引正气
疏导气血的指标
看到针麻诱导后出现外周血管舒张
容积脉搏波加大等变化.针麻对外周血流的影响
启示我们考虑到针刺对脑中枢内与镇痛和调整作用有关核团的微循环是否也有影响
它与吗啡的作用有无不同
因此
我们进行了以下的实验观察.Based upon our previous study of acupuncture analgesia and the effeet ofmorphine upon locus coeruleus and raphe nucleus
Bu ChE histochemical reactionwas applied to fresh brain sections from cryostat for demonstrating the changesof the capillary calibers
with the purpose of observing the influence ofbothtypes of analgesia upon above nuclei.142 healthy
adult
male rats were selected and then divided at random into acupuncture
morphine
and control groups.After measuring the painthreshold
the brains were taken out immediatly for histochemical observationof Bu ChE reaction.The calibers of capillaries of the both nuclei of thesegroups were then measured with a spiral auto-micrometer and treated statis-tically.In comparison with the control
the mean distension of calibers of acu-punctured nucleus raphe dorsalis was measured without any statistical sig-nificance.But that of the locus coeruleus presents a prominent difference.The mean distension of calibers in both nuclei of the morphine group wasalso prominent.The result showed that both acupucture and morphine produced effectiveanalgesia
though there were no statistical significance between AChE amo-uunts in locus coeruleus and raphe nucleus of the morphine group and the acu-punctured group in the previous study.In this study
it presented a significantincrease of distension of calibers in both nuclei of morphine group
and yetonly thecalibers in the locus coeruleus were distended by acupuncture.Ther-efore it indicates that there are either differences or similarities in these twokinds of analgesia.The mechnism of acupuncture analgesia and regulation was discussed inthis paper.
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