临床和实验研究结果表明

针刺内关可以治疗多种疾病。为阐明这种效应的机制

研究针刺信息的作用途径

一些作者对针刺“内关”的传入神经通路等进行了积极的探讨。我们曾观察过电针猫“内关”区的脊髓背根诱发电位节段分布范围

分析了内关传入途径与正中神经

尺神经和桡神经的关系

认为内关传入途径与正中神经关系最密切。本文以猫颈-胸导联叠加的ST段电位值变化为急性心肌缺血性损伤的指标

以正中神经复合动作电位为神经纤维类别兴奋的指标

分析电针“内关”效应的传In previous work

it was suggested that the median

ulnar and radial nerves were the composition parts of the signal afferent pathways exerted by electric stimulation "Neiguan". The median nerve might play an important role in this action. The purpose of this paper was to further study the relation between the afferent signal along the median nerve and the therapeutic effect in treatment of acute myocardial ischemia in cats

Experiments were performed in anesthetized with pentobarbital na- trium(35mg/kg)

flaxedil immobilzed and artificially ventilated cats. Forty- nine experimental animals were divided into four groups: 1)cutting median nerve group; 2)group Ⅱ fiber excition; 3) group Ⅲ fiber excition group; 4) control group. The heart was exposed through a left thoracotmy in the fourth intercostal space. Applying the method of ligating the LAD coro- nary artery for 15 min

a state of regional myocardial ischemia was made. The ligation was then loosed and the ST values observed at 5′、10′、 l5′、20′、30′、40′、50′and 60′after loosening respectively. The median nerves were isolated at about 3 cm above the wrist Joint and the level of brachial-plexus in cats. The poteutial changes of the ST values of lead C-T ECG averaged 8 times by computer 7S06A were used as the index to evaluate myocar- dial ischemia and its recovery course. stimulation of electrical pulse for "Neiguan" point was given by the electronic stimulator SEN-3101 through isolator (0.2ms duration

100 ms interval). During the experiment

first

in order to determine the stimulating intensity of electro-acup. at "Neiguan"

inducing group Ⅱ or Ⅲ

fiber excitation

the compound action potentials of median nerves were recor- ded. Next

recording the ECG of C-T lead as control before ligation

LAD coro nary artery was ligated for 15 min

and then loosed slowly. The animals of 1-3 groups of 1-3 groups received the electric impulses on both "Naiguan"

lasting for 20 min immediately at loosing the Jigation. The recording method and experimental procedure were the same in the control group except the electroacup. Folgwings are the main results of our observation: Theire was no statistical difference of ST values of lead C-T ECG between the four groups before ligation. Fifteen min after ligation

the ST values were elevated markedly

but there were no statistical signifi- cances between the four groups. According to statistical analysis with Ridit method

the result showed that there was a marked difference between Ⅱ

Ⅲ fibers excition group and the control group at all experimental processes

but between Ⅱ fibers group and control group only at 5-20 min; and no marked difference be- tween cutting median nerve and the control. The above mentioned results show that: 1) There was therapeutic effect of acute ischemic myocardial injury improved by electroacupuncture at "Neiguan" point in cats. 2) The median nerve might play an important role in the afferent pathway of the above mentioned effect

when group Ⅱ fibers were ex- cited the therapeutic effect appeared. When both group Ⅱ and Ⅲ fibers were excited

better effects of electroacupuncture at "Neiguan" point were obtained.