针感与大脑皮层的感觉整合机能密切相关。Marshall和Woolsey等早就应用诱发电位技术研究躯体感觉的皮层定位;近代出现的累加技术

更为体感诱发电位的研究提供了方便。本工作用猫

参照人体穴位的解剖位置

模拟穴位和非穴位区

以SI区皮层诱发电位为指标

探讨穴位反应的特异性。方法实验用20只成年猫

雌雄不分

体重2.1～4.2公斤。在氯醛糖(70毫克/公斤体重)麻醉下进行手术

暴露左侧大脑皮层后Many clincal and animal experiments have indicated that acupuncture can produce different effects at different acupoints. It Shows that the fu- nctions of acupoints are specificity. In the presentstupy the cortex evok- ed retponse elicited by stimulation of acupoints and nonacupoint was re- corded to inquire the relative specificity of acupoints. The experiments were performed on 20 adult cats anesthetized with a single dose of a-Chloralose. The concenrtric circles electrodes were used to stimulate the acu "Hegu"

the "Wan'gu" and the nonacupoint that was between the two points. The parallel two electrodes were used to elicit SI somatosensory evoked potentials

using the computer ATAC-350 to average and recorded by X-Y recorder. Twenty cats were observed for 98 times. At the sme level local of cat's forelimb

during stimulating the"Hegu"

all of the cats produced the evo- ked potential from opposite cortex

using the same stimulation on the nonacupoint that was beside 1cm to the "Hegu"

all of the experiments can not get the evoged potential

but during stimulating the "Wangu" with the same stimulation

the evoked potentiel appeared again.inall of the cats. The cortex evoked patentials of "Hegu" were a biphasic positive-negative wave

peak-laiency 43.32±0.74 ms

amplitude 51.98±2.26uv duration 42.73 ±1.29 ms. The cortex evoked potentials of "Wangu" were also a biphasic positive-negative wave

peak-latency 49.40±1.41 ms

amplitude 44.57± 1.89μv duration 44.70±1.48 ms.These data show that the peak-latency of "Hegu" significantly differed(P<0.01)from the peak-latency of "wangu" and the amplitudes were also significative difference (P<0.05) between the two acupoints

but the duration show no signlficant difference (P> 0.1). These results suggest that the cortex evoked potential of acupoint "He- gu" point significantly differed from "Wangu" and the cortex evoked potentials were even more significative difference between the acupoints ("Hegu"

"Wangu") and the nonacupoint. Consequently

there are rela- tive specificity not only between the acupoint and nonacupoint

but also between the two acupoints.