许多针刺研究的工作提示

中枢递质的活动与针刺效应有关。随着微量测定等技术的发展

已有较多的研究者以比较直接的方法观察了针刺对中枢递质的影响

为分析中枢递质参与针刺效应的机制提供了明确的证据

本文综述这方面的研究概况。一、内阿片肽(Endogenous Opiate Peptides EOP) 1.针刺使脑脊液内EOP含量升高 Sjolund等对9例患有慢性痈的病人用表面电极刺激穴位镇痛

并测定刺激前后腰部脑脊液中EOP含量的变化。其中4人疼痛的部位在腰椎水平

电刺激部位也在相应的节段

电极刺激穴位镇痛时

脑脊液中EOP含量明显升高;另5人的疼痛部位在胸部或头This review summarized 116 articles on the acupuncture action upon the central neurotransmitters. From the sufficient data

it was shown that acupuncture can significantly affect the activities of the neurotransmitters including endogenous opioid peptides

serotonin

noradrenaline

dopamine and acetylcholine. The authors believe that the changed functions of the ne- urotransmitter systems induced by acupuncture not only lead to analgesia but also cause other effects.