大量资料表明

中枢许多核团存在对伤害性刺激起兴奋反应和抑制反应的两类神经元。本室以往的工作证明

丘脑束旁核同时存在痛兴奋和痛抑制神经元

通过两者的相互配合活动

共同调制疼痛的感受。另有文章报道

电刺激外周神经可使视前区神经元的电活动出现兴奋或抑制反应。为了解视前区痛兴奋与痛抑制神经元的关系

及视前区与束旁核两个神经元的同时电活动

本文用两只玻璃微电极同时记录视前区或视前区与束旁核两个神经元的放In 8 rats

12 pairs of the simultaneous electric activities of pain-exci- tation neurons (PEN) and pain-inhibition neurons (PIN) in preoptic area were recorded with two glass microelectrodes. The results showed that PEN and PIN in preoptic area existed and acted simultaneously. In 25 rats

27 pairs of the simultaneous electric activities of PEN and PIN in parafascicular nucleus and in preoptic area were recorded. Noxious stimuli simultaneously provoked the increasing discharges of two PEN and decreasing discharges of two PIN in parafascicular nucleus and in preoptic area. It is considered that

PEN and PIN in parafascicular nucleus and in preoptic area may take part in the integration of paim sensation simulta- neously.