近年来我们实验室以猫丘脑髓板内核群(中央中核CM;束旁核Pf;中央外侧核CL)神经元的伤害性放电反应为指标

观察到大脑皮层体感Ⅱ区(SⅡ)对上述神经元的伤害性反应及针刺镇痛效应有下行调节作用。从皮层到丘脑髓板内核群的这条下行通路中有一中间结构—尾核。尾核参与疼痛的调节

在形态上

尾核与CM、Pf、CL有直接的纤维联系

也有纤维投射到皮层

并接受来自皮层的纤维投An observation about the effect of stimulation SII or electroacupunct- ure on nociceptive reponse of CM neurons after lesion of the head of caud- atum bilaterly was performed. The experimental were carried out on ad- ult cats. The glass microelectrode technique was used and the discharges of CM neurons were attanuated within 1-3.5' after ceassion of stimulation of SII(n=19) or electroacupuncture Zusanli and Huantiao (n=13). There was a statistical significance it was compared with that of the result before sti- mulation(P<0.005). So it was suggested that the caudate nucleus may not be involved in the influence of SII on the effect of pain acupuncture analgesia in intralaminar nuclei.