用胃肠电活动作为胃肠功能和胃肠道疾病诊断和判定疗效的指标

已进行数十年的研究

但到目前为止

仍存在很多问题

为将胃肠电活动应用于临床

作为针麻胃肠道手术和胃肠道疾病时胃肠功能变化的指标

我们研究了狗胃肠道电活动的基本规律

以作为临床应用的参考。实验方法用狗为实验动物

雌雄不拘

体重为10～18公斤

在戊巴比妥钠(Pentobarbi-tal sod)麻醉下

按外科常规手术操作

Unanesthetized trained dogs with implanted electrodes in the stomach and intestinal wall were prepared for the study of the rhythmic pattern and characteristics of the gastrointestina electrical activity. The results were as follows: In the fasting condition

the frequency of the slow wave of the gastroelectric activity may be divided into three rhythmic patterns: (1)Slow wave or primary wave. The frequency of this wave pattern was 5.1±0.3 cycles/minute. It accounted for 92% of the whole experiment.(2)Fast slow- wave. The frequency of this wave pattern was 13.4±1.7 cycles/minute and it accounted for 7.4% of the whole experiment.(3)Premature slow-wave. This happened just like an extra-systole of the heart. The premature slow- wave was always followed by a compensatory pause. This wave pattern occurred in the experiments very often. In the fasting condition

an alterna- tion cf period of quiescence and electrical spiking activity occurred at regular intervals. It was called interdigestive myoelectric complex(IDMEC). The cycl'c activity of the interdigestive myoelectric complexes of the sto- mach and small intestine may be changed by both splanchnicotomy and vagotomy

and by intravenous injection of atropine or hexamethonium

in- travenously or cerebral intraventricle injection of morphine or gastin and by subcutaneous local abscesses. Acupuncture at "Zusanli" had little effects on the slow wave of the gastroelectric activity

bur as a result of acupu- ncture the amplitude and frequency of the fast wave increased. In normal animals acupurcture at Zusanti" had no effect on the interdigestive myo- electric complex bat an obvious regulatory action of the IDMEC on the dogs with subcutansous local abscess was observed.