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河北医学院
纸质出版日期:1987
移动端阅览
袁德霞, 付志良, 应国华, 等. 针刺镇痛对肝脏超微结构的影响[J]. 针刺研究, 1987,(1):52-57.
Yuan Dexia Fu Zhiliang Ying Guohua Li Wenzhen Wang Yafei Zhao Yuzhen. EFFECT OF ACUPUNCTURE ON ULTRASTRUCTURE OF LIVER IN RATS[J]. Acupuncture research, 1987, (1): 52-57.
在应激、中毒及机体损伤时
肝可迅速合成大量必需物质
以供机体调整、稳定及修复之用
四氯化碳引起的肝损伤
用灸可改善肝功能。血清转氨酶(GPT)及胆固醇均下降
针刺可促进肾上腺皮质激素(ACTH)及糖皮质激素分泌增多
后者又加强肝糖元异生及血糖升高
这些实验说明针灸对肝脏有一定的影响
但对其实质和超微结构究竟有何改变
需要进一步探讨
为此本组进行以下实验。
we selected 10 adult male rats(weight 165-250g)
which were divided into control group and experimental group and were used in this studies for electron microscopic observation. In control group.The hepatocyte contains large amount of rough end- oplasmic reticulum(RER)and smooth endoplasmic reticulum(SER)in the central and intermediate area of classic lobules.The glycogen a-particles mainly accumulated in periphery area of classic lobules.The hepatic cell possessed abundant mitochondria which was always closely surrounded by flat cisternae of RER. After the acupuncture experiment.The hepacal cell body and nucleus was hypertrophy and nucleolus were predominant.In the hepatocyte the number of RER
free ribosome and polysome were increased
the end of cisternae of RER appeared dilated and the associated ribosome were decrea- sed.So that it was called degranues phenomenon.Cisternaes and tubules of SER were dilated and anastomosed one another to form the irregular meshwork thatistributed throughout in the cytoplasma.The swelled mito- hoadria were with tubule cristae which was transformed from the plate cristae.The glycogen α
β-particles filled the cytoplasma of hepatocytes in three areas of the classic.The Golgi complex well developed and seted near the dilated bile canaliculi(B.C)that was with more longer microvilli pro- jected into the lumen.The junction complex in periphery of B.C.was not changed.Dissess space was distended and filled numerous microvilli which branched and anastomosed with each other formed loose meshwork.The fat-storing cell extend the plasmic processes.Some of which arrenged along endothelial lining.In the cytoplasm of this cell
there were abundant RER
free ribosome and polysome.The cisternae of RER possessed flocculent material of low electron density.It is appeared that the synthesis of fat- storing cell was increased.In addition
there were a number of large lipid droplete in the cytoplasm of this cell.The phagocytosic activity of Kupffer's cells was predominently increased. At last
the relationship between the control group and the acupunc- ture experimental group was discussed in this article too.
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