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1. 上海第一医学院中西医结合研究所妇科虚证研究室
2. 上海第一医学院妇产医院
3. 上海第一医学院针刺原理研究室
纸质出版日期:1986
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俞瑾, 郑怀美, 陈伯英. 电针促排卵和血β-EPIS、手部皮肤温度变化的关系[J]. 针刺研究, 1986,(2):86-90.
RELATIONSHIP OF HAND TEMPERATURE AND BLOOD D--ENDORPHIN--LIKE IMMUNOREACTIVE SUBSTANCE WITH ELECTROACUPUNCTURE INDUCTION OF OVULATION[J]. Acupuncture research, 1986, (2): 86-90.
电针刺激可以促进排卵
可以治疗排卵功能障碍性月经失调和不孕症
我们在电针后手部皮肤温度上升者针麻效果较好
和针刺可引起人体β-内啡肽在血中水平变化报道的启示下
曾报道电针促排卵的效果和体内雌激素作用水平及电针后手部皮肤温度变化(Hand Lempertuve changes after dec-tro-acupuncture、简称HTCEA)
血β-内啡肽样免疫活性物质(β-Endorphin-like immunoreaactive substtamces
简称β-EpIS)变化有一定关系。本文对以上结果作进一步探讨。材料和方法Electroacupuncture(EA) is proved to be a method of ovulation induction. In present study
11 chronically anovulatory patients (polydystic ovarian disease 9
hypogonadotropic amenorrhea 1
oligomenorrhea 1) were treated with EA in 13 cycles. On the 10th day of each cycle hand temperature(HT) after EA and blood β-endorphin-like immunoreactive substance (β-EIS) levels before and after EA were collected. 5 heslthy women with normal menstruation were recuited as controls. 6 of the 13 cycles treated with EA showed ovulation
while the other 7 cycles were failed. No regular change was seen in HT of the 5 onrmals. In the 13 anovulatory cycles
increased HT occurred in 6 cycles
of which 5 cycles showed ovulation after EA. 7 cycles showed decreased HT
and only one of them manifested ovulation after EA (p
<
0.05). Innormal cases
blood β-EPS leves before and after EA were fluctu- ater
and returned to preacupunctural levels at 30 minuter after withdraw of needles. The highest mean level was 193.94
(±)
144.04fmol/ml. In the 13 anovulatory cycles
basic blood β-EPS levels on the 10th day of thecycle were higher but not significant than that of the normoal women. After EA these blood levels of the 6 cycles resulting in ovulution after EAT either declined or maintained at levels at levels within the range of the normal cases
and blood levelds of the 7 cycles failing to show ovulation after EA were significantly higher than the normals' and throse that ovulated (p
<
0.05). Cycles which showed increase of HTCEA were more likely to associate with a declination of blood β-EPS after FA
but in cycles where HTC decreased
blood β-EPS levels elevatedafter EA. There appcars to be a negative correlation between the tendency of blood β-EPS changs after EA and HTC(p
<
0.01). HTC may be utilized to reflet the state of sympathetic activic. this study suggests that in many anovulatry cases the excessive sympathetic activity and hypothalamic-pituitary-ovarian disorder can be regulated by EA
monitoring of HTC may provide a rough but simple method for pre- dicting the effect of EA ovulation induction
and bllod β-EPS plays an important role in the mechanism of EA induction of ovulation.
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