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1. 中国中医研究院针灸研究所
2. 中日友好医院病理室
纸质出版日期:1986
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黄为敏, 黄坤厚, 戎象棣, 等. 电针对失血性休克大白鼠心房心钠素影响[J]. 针刺研究, 1986,(4):241-245.
EFFECT OF ELECTROACUPUNCTURE ON ATRIOPEPTIN GRANULES IN RAT'S ATRIUM WITH HEMORRHAGIC SHOCK--IMMUNOCYTOCHEMICAL OBSERVATION[J]. Acupuncture research, 1986, (4): 241-245.
祖国医学很早就提出针刺“人中”有急救垂危病人复苏的作用。一些临床和实验研究证明针刺“人中”有抗休克的作用
并提出针刺抗休克可能与某些神经内分泌体液因素有关。用组组化学方法从形态学上证明
针刺“人中”可使失血性休克家兔心肌内减少脱失的儿茶酚胺萤光得到恢复使之接近正常。心钠素(Cardionatrin)是近年从人和大白鼠心房组织中分离提取的一类生物活性多肽
有人认为是新的内分泌39 adult healthy male rats were divided evenly into three groups. The rats attacked with hemorrhagic shock by bleeding via left femoral artery. Bleeding was continued till mean blood pressure of 40 mmHg was obtained. The state of hypotension was maintained for 1(1/2) hours in hemorrhagic shock group. 1/2 hour after bleeding electroacupuncture at "Renzhong" point was given for 1 hour in electroacupuncture group. The rat's hearts were excised after experiment. Peroxidase antiperoxidase immunocytochemistry method of Stenberger was used to demonstrate the atriopeptin like immu- noreactive granules in rat's atrium. The atriopeptin like immunoreactive granules in hemorrhagic shock rat's atrium were increased than that of normal and electroacupuncture group. The immunoreactivities of granules in atrial cardiocytes were marked increased by hemorrhagic shock. The density and distribution of atriope- ptin immunoreactive like granules in rat's atrium of the control showed a similar pattern to that of hemorrhagic shock animals given electroacupu- neture. It was indicated in our result that the electroacupuncture might have an anti-hemorrhagic shock effect and atriopeptin as one of the neuroend- ocrine might play a certain role in electroacupuncture anti-shock.
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