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重庆医学院生理教研室
纸质出版日期:1985
移动端阅览
费汝为, 黄仲荪. 刺激清醒猫内脏大神经时延髓网状细胞电活动、行为变化及针刺效应的观察[J]. 针刺研究, 1985,(4):259-263.
THE EFFECT OF ELECTROACUPUNCTURE ON SINGLE BULBAR RETICULAR CELLS AND BEHAVIOR RESPONSES INDUCED BY THE SPLANCHNIC NOCICEPTIVE STIMULATION IN CONSCIOUS CATS[J]. Acupuncture research, 1985, (4): 259-263.
在痛觉生理和针刺研究中
人们可以看到中枢神经细胞对伤害性刺激呈现不同形式的电反应
其中增频反应往往被视作一种痛反应
针刺体表某些部位可以使上述反应减弱
因之常依此来描述针刺镇“痛”效果。但是
这类实验往往在麻醉或肌肉麻痹条件下的动物身上进行的。细胞放电反应的瞬间变化是否能全面反映镇痛效果?本文用清醒猫为对象进行上述问题的探讨。
The chronic microelectrode techniques were carried out on 23 cats. The response of a single unit activity of bulbar medulla and the behavior respo nses were recorded when the intenstive stimulus applied to the central end of splanchnic nerve. Among 128 neurons from 18 cats
the frequency of neuronal discharges was increased in 100 units (about 78.1%)
and decreased in 27 units (abo- ut 21.1%). The pain response
increasing abdominal muscle contration and the pupil dilation occurred concomitantly. with the change of neuronal di- scharges. The behavior responses of entire body
however
were elicited when the intensity of noxious stimulation was increases signficantly. In most conscious cases
the changes of bulbar unit discharge
either increasing or decreasing
were depressed by electroacupuncture
but there was no significant change in the behavior responses arised from the spla- nchnic stimulus. It is therefore concluded that the depression of unit discharge in ce- ntral nervous system
in general
may serve as an analgesic index in the research of electroacupuncture. However
the inhibition of behavior resp- onse of pain would be one of the much more effective criteria in a true estimation of acupuncture anaesthesia. The drowsy signs were produced in 13 out of 27 experiments from 6 cats while the microelectrode was inserted into the reticular formation of medulla oblongata. The relationship between drowsy and electroacupunctu- re analgesia
however
is not understood clearly
and needs further studies.
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