腓深神经传入冲动抑制防御性升压反应时脑脊液内单胺类物质的变化

夏萤; 张安中; 曹小定; 唐琴梅; 徐修容

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腓深神经传入冲动抑制防御性升压反应时脑脊液内单胺类物质的变化

更新时间：2023-08-11

- 腓深神经传入冲动抑制防御性升压反应时脑脊液内单胺类物质的变化
- CHANGE OF MONOAMINE NEUROTRANSMITTERS IN CSF DURING INHIBITION OF DEFENSIVE HYPERTENSIVE REACTIONS BY INPUTS OF DEEP PERONEAL NERVE
- 针刺研究 1989年第3期页码：339-343
- 作者机构：
  
  1. 上海医科大学神经生物学教研室
  2. 中国科学院上海药物研究所
- 作者简介：
- 基金信息：
  
  世界卫生组织资助项目
- DOI：
  中图分类号：
- 纸质出版日期：1989
- 稿件说明：
移动端阅览
夏萤, 张安中, 曹小定, 等. 腓深神经传入冲动抑制防御性升压反应时脑脊液内单胺类物质的变化[J]. 针刺研究, 1989,(3):339-343.

Xia Yin Zhang Anzhong Cao Xiaoding (Department of Neurobiology, Shanghai Medical University)Tang Qinmei Xu Xiurong. CHANGE OF MONOAMINE NEUROTRANSMITTERS IN CSF DURING INHIBITION OF DEFENSIVE HYPERTENSIVE REACTIONS BY INPUTS OF DEEP PERONEAL NERVE[J]. Acupuncture research, 1989, (3): 339-343.
夏萤, 张安中, 曹小定, 等. 腓深神经传入冲动抑制防御性升压反应时脑脊液内单胺类物质的变化[J]. 针刺研究, 1989,(3):339-343. DOI：

Xia Yin Zhang Anzhong Cao Xiaoding (Department of Neurobiology, Shanghai Medical University)Tang Qinmei Xu Xiurong. CHANGE OF MONOAMINE NEUROTRANSMITTERS IN CSF DURING INHIBITION OF DEFENSIVE HYPERTENSIVE REACTIONS BY INPUTS OF DEEP PERONEAL NERVE[J]. Acupuncture research, 1989, (3): 339-343. DOI：

摘要

资料表明

兴奋下丘脑防御反应区(Hypothamic Defence Area

HDA)可导致心血管交感活动亢进及其它多种功能活动的改变

这可能与脑内某些核团的单胺类递质活动有关

电针“足三里”或电刺激腓深神经(Deep Peroneal NerveStimulation

DPNS)能抑制刺激 HDA 诱发的升压反应和室性期前收缩等防御反应性表现。但在此抑制过程中

脑内单胺类递质的活动尚无明确证据。

Abstract

Our previous work has indicated that excitation of hypothalamic defence area (HDA) could lead to an increase in the release of central monoamine neurotransmitters

pressor and other defence responses.The present experiments showed that stimulation of deep pernneal nerve with a current of low frequency and low intensity could inhibit the pressor

abolish the increase of noradrenaline and its metabolite MHPG and attenuate that of 5-HIAA (a 5-HT metabo-lite)

dopamine and its metabolites DOPAC and HVA in CSF.The data suggest that inputs of deep peroneal nerve may inhibit the increased release of cental monoamine neurotransmitters

and then defence reactions;and inhibition of NA release in some nuclei of the brain is an important mechanism of inhibition of defenee pressor by inputs of deep peroneal nerve.

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