Zhang Kejian and Gao Jiyuan. EFFECTS OF ELECTRO-ACUPUNCTURE ON LEUKOCYTE MIGRATION AND STUDIES OF THE EFFECTIVE MECHANISM IN RATS OF PLEURISY[J]. Acupuncture research, 1988, (3): 226-230.
Zhang Kejian and Gao Jiyuan. EFFECTS OF ELECTRO-ACUPUNCTURE ON LEUKOCYTE MIGRATION AND STUDIES OF THE EFFECTIVE MECHANISM IN RATS OF PLEURISY[J]. Acupuncture research, 1988, (3): 226-230.DOI:
电针刺激对胸膜炎大鼠白细胞游出的影响及其作用机制的研究
摘要
一系列的临床观察和实验研究证实
针刺可提高患病机体的防御能力
对炎症过程进行调整而抑制炎症的病损。临床观察发现
针刺能有效地治疗很多急、慢性炎症。实验研究亦表明
电针刺激可有效地抑制炎症的渗出和肉芽组织增生。但有关针刺对Electro-acupuncture could suppress the leukocyte migration to the inflam- matory focus in the rats of carrageenan-pleurisy.The result of analyses of stepped regression by micro-computer indicated that enhanced leukocyte chemo- taxis in inflammation is a main factor which effects leukocyte migation. Leukocyte chemotaxis is regulated by intracellular cAMP and cGMP levels. This paper demonstated that electro-acupuncture might inhibit leukocyte chemo- taxis
increase intracellular cAMP level which decreased during inflammation and decrease intracellular cGMP level which increased during inflammation. The effects of electro-acupuncture on cAMP and cGMP are probably substance basis inhibiting leukocyte chemotaxis