In this experiment

we have obsevved whether the electro-acupuncture (EA)possese strenthening effects on immune function after intracerebroven- tricular(ICV)injections of dihydroxyphenylserine(DOPS)or electical stim- ulation of locus coeruleus(LC)raises the central norepinephrine(NE)levels or excites the activity of central NE-ergic neurons

respectively. The increase of EA-mediated T-lymphocyte transformation ability was suppressed and the antibods produced by B-lymphocyte system was raised after ICV injected DOPS which raise the NE levels in brain.The influenoe factors of DOPS upon the increase of EA-mediated immune function were complicated Among them

the factor in dosage-effect of DOPS may be involved in it. The ability of T-lymphpcyte transformation and lysozyme levels were markedly increased in stimulated LC group or in stimulated LC plus EA group. It showed that the immune functions could be increased when stimulating LC which can excite the abiity of central NE-(?)rgic neurons.At the sam time

the strenthening effects of immune function induc(?)d by stimulating LC may cooperated with EA.