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中国中医研究院针灸研究所
纸质出版日期:1989
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孟竞璧, 刘瑞庭, 须惠仁, 等. 电针对心肌缺血性损伤时心肌节段长度和左室内压——长度环的影响[J]. 针刺研究, 1989,(4):435-441.
EFFECT OF ELECTRO-ACUPUNCTURE ON THE SEGMENT LENGTH OF THE MYOCARDIUM AND THE LEFT INTRAVENTRICULAR PRESSURE-LENGTH VECTOR LOOP DURING EXPERIMENTAL ACUTE MYOCARDIAL ISCHEMIC DAMAGE[J]. Acupuncture research, 1989, (4): 435-441.
孟竞璧, 刘瑞庭, 须惠仁, 等. 电针对心肌缺血性损伤时心肌节段长度和左室内压——长度环的影响[J]. 针刺研究, 1989,(4):435-441. DOI:
EFFECT OF ELECTRO-ACUPUNCTURE ON THE SEGMENT LENGTH OF THE MYOCARDIUM AND THE LEFT INTRAVENTRICULAR PRESSURE-LENGTH VECTOR LOOP DURING EXPERIMENTAL ACUTE MYOCARDIAL ISCHEMIC DAMAGE[J]. Acupuncture research, 1989, (4): 435-441. DOI:
临床上针刺治疗冠心病
在病人的心尖搏动图观察到:针刺可以降低舒张期终末压
并可改善心肌顺应性。在动物实验性心肌缺血性损伤中观察到针刺具有增加左室内压——压力变化上升速率(P-dp/dt)
并使心肌纤维收缩成份缩短速度(VCE)等参数明显加快
表明针刺可以增强心肌收缩力
改善心肌纤维收缩成份。为了探讨心In order to explore the effect of electroacupuncture on myocardial contracti-bility in the ischemic area
a medical Silicon tube with Saturated Copper Sulf-ate was used as length gauge and set at 5mm below the ligated marginalis andparalleled with blood vessel. The signals of the length and the pumping functionwere transmitted into the polygraph and the signals of the left intraventricularpressure (LVP) and the segment length (L) were conveyed into the oscilloscopeto display the LVP-L vector loop. Electroacupuncture was applied bilaterally on Neiguan points with electricalimpulses of strength 5 volts. The arterie coronaria was ligated for 20 min andthen loosened. electro-acupuncture was performed and lasted 20 min. Imbedd-ed the needle for 30 min
then ligated at the original position and never loose-ned again; 15 min later
the electroacupuncture was performed for the secondtime
lasting 20 min
then the needle was with drawn and observed for 15min. The Epicardial ECG was used as the standard to judge the degree of themyocardial ischemic injury. A comparison was made between the parametersdetermined 15 min after ligation and all the procedures after electroacupunture.There were 15 dogs in the electroacupuncture group and 15 in the control group. 1. The mean amplitute of segment length of the myocardium was 23mmbefore ligation. 15 min after ligation
it slightly decreased in the electroacupu-ncture gronp while slightly increased in the control group. There was no obviousdifference in the duration of the amplitute between the two groups. The twoparameters determined before ligation and 15 min later
were not statisticallysignificant between the two groups (P>0.1). 2
In the electroacupuncture group
the amplitute of the myocardial segment length determined 15 min after ligation was 22.65±11.03mm. There was nostatistical difference between the two gorups (P>0.1). It was slightly decreasedin the electroacupuncture group during imbedding the needle after performing electroacupuncture
and slightly increased in the three procedures after the second ligation. Comparing it with that determined 15 min after ligation
there was no difference (P>0.1). In the control group
although the ligation was loosened 20 min after ligation
the amplitute declined gradually. It changed from positive to negtive. It was -43.87±17.87mm after withdraw of the needle
which correspo-nded to those of the procedures of performing electroacupuncture
imbedding needle
the second ligation
the second electroacupuncture and the procedure after withdrawing the needle. There was statistical difference compared with that determined 15min after ligation (P<0.05). In the electroacupuncture group
there was no great change in the amplitute of the myocardial sogment length
while in the control group
it declined gradually. There was statistical difference between the two groups (P<0.05). But there was no statistical difference in the duration of the amplitute between the two groups. 3. Opposite waveform of the myocardial segment length appeared at 4 dogsfor each group after ligation
taking 26.67% respectively. After withdrawing theneedle
7 dogs in the control group showed opposite waveform
taking 46.67%
while in the electroacupuncture group
the porcentage was 26.67%. The wave of one dog in the electroacupuncture group sometimes changed from opposite to positive
and sometimes from positive to opposite. 4. Observation of LVP-L vector loop: The rhombic figure of the LVP-L vector loop changed its original clockwise direction to counterclockwise direction after ligation
and the typical ischemic figure "8" appeared
which corresponded to the opposite waveform of the myo-cardial segment length appeared after ligation and indicated that the myocardium in the ischemic area become soft and opposite activity. The LVP-L vector loop for which the opposite waveform did not appear showd the figure that the length increased mainly and the width secondarily. The results described above demonstrates that electroacupuncture may improve and protect the myocardium of ischemic area
increase its tension
strengthen its contractibility
inhibit or reduce the myocardial protrusion in the ischemic area during systole
which is beneficial to the improvement of the pumping function of the heart.
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