吗啡和电针对伤害性刺激诱发体感皮层单位放电的时锁和非时锁反应的影响

陈助华; 陈培熹

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吗啡和电针对伤害性刺激诱发体感皮层单位放电的时锁和非时锁反应的影响

更新时间：2023-08-11

- 吗啡和电针对伤害性刺激诱发体感皮层单位放电的时锁和非时锁反应的影响
- EFFECTS OF MORPHINE AND ELECTROACUPUNCTURE ON THE TIME LOCK AND NOT-TIME LOCK RESPONSES OF CORTICAL UNIT DISCHARGES EVOKED BY NOCICEPTIVE STIMULATION IN CATS
- 针刺研究 1991年第2期页码：95-99
- 作者机构：
  
  1. 中山医科大学生理教研室
  2. 中山医科大学生理教研室,广州
  3. ,广州
- 作者简介：
- 基金信息：
- DOI：
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- 纸质出版日期：1991
- 稿件说明：
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陈助华, 陈培熹. 吗啡和电针对伤害性刺激诱发体感皮层单位放电的时锁和非时锁反应的影响[J]. 针刺研究, 1991,(2):95-99.

Chen Zhuhua Chert Peixi. EFFECTS OF MORPHINE AND ELECTROACUPUNCTURE ON THE TIME LOCK AND NOT-TIME LOCK RESPONSES OF CORTICAL UNIT DISCHARGES EVOKED BY NOCICEPTIVE STIMULATION IN CATS[J]. Acupuncture research, 1991, (2): 95-99.
陈助华, 陈培熹. 吗啡和电针对伤害性刺激诱发体感皮层单位放电的时锁和非时锁反应的影响[J]. 针刺研究, 1991,(2):95-99. DOI：

Chen Zhuhua Chert Peixi. EFFECTS OF MORPHINE AND ELECTROACUPUNCTURE ON THE TIME LOCK AND NOT-TIME LOCK RESPONSES OF CORTICAL UNIT DISCHARGES EVOKED BY NOCICEPTIVE STIMULATION IN CATS[J]. Acupuncture research, 1991, (2): 95-99. DOI：

摘要

过去研究电针对痛敏单位放电的影响时

大多数报道都以非时锁反应(单位时时内放电数量或平均放电率的变化)为指标

也有用时锁反应(对刺激有效固定的时间关系的短暂反应)为指标。我们对这两种反应进行了对比

两者反映角度不完全相同。本文以伤害性刺激猫的腓浅神经(PN)诱发In order to study the effects of morphine and eletro-acupuncture(EA)on non-time-lock respone (N-TLR)and time-lock response (TLR)of nociceptive unit disehasges.N-TLR was shown by interspike interval mean function (ISIMF)and TLR by normalized cross-covariance function (NCCVF)reflecting the relationship between stimulation and response. The results showed that the N-TLR elicited by the noxious stimulation appeared as a decrease of ISIMF.Which was depressed obviously by EA and morphine

but inhibitory effect of EA was more rapid than morphine

that both EA and morphine inhibited mainly the late peak of the NCCVF elicited by the noxious stimulation

but inhibitory effect of EA was more rapidly developing and moqe quickly recovering than that of morphine.The inhibi- tory effect of EA on the early peak was very little.From above results it was suggested that the P-ED elicited by the noxious stimulation could be inhibited by both EA and morphine

but the degree and the speed of inhibtion were difference.

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