伤害性刺激对大鼠丘脑腹后外侧核痛兴奋神经元和痛抑制神经元放电的影响及电针对其调制作用

孙明智; 李玉荣; 张季叶; 边景檀

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伤害性刺激对大鼠丘脑腹后外侧核痛兴奋神经元和痛抑制神经元放电的影响及电针对其调制作用

更新时间：2023-08-11

- 伤害性刺激对大鼠丘脑腹后外侧核痛兴奋神经元和痛抑制神经元放电的影响及电针对其调制作用
- EFFECTS OF NOXIOUS STIMULI ON THE DISCHARGES OF PAIN-EXCITATION NEURONS AND PAIN-INHIBITION NEURONS IN THE NUCLEUS VENTRALIS POSTEROLALIS OF THALAMUS IN THE RAT AND A MODULAING ACTION OF ELECTROACUPU-NCTURE ON ITS ELECTRIC ACTIVITIES
- 针刺研究 1991年第1期页码：19-22
- 作者机构：
  
  哈尔滨医科大学基础医学研究所
- 作者简介：
- 基金信息：
  
  中国科学院基金
- DOI：
  中图分类号：
- 纸质出版日期：1991
- 稿件说明：
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孙明智, 李玉荣, 张季叶, 等. 伤害性刺激对大鼠丘脑腹后外侧核痛兴奋神经元和痛抑制神经元放电的影响及电针对其调制作用[J]. 针刺研究, 1991,(1):19-22.

Sun Mingzhi, Li Yurong, Zhang Jiye, et al. EFFECTS OF NOXIOUS STIMULI ON THE DISCHARGES OF PAIN-EXCITATION NEURONS AND PAIN-INHIBITION NEURONS IN THE NUCLEUS VENTRALIS POSTEROLALIS OF THALAMUS IN THE RAT AND A MODULAING ACTION OF ELECTROACUPU-NCTURE ON ITS ELECTRIC ACTIVITIES[J]. Acupuncture research, 1991, (1): 19-22.
孙明智, 李玉荣, 张季叶, 等. 伤害性刺激对大鼠丘脑腹后外侧核痛兴奋神经元和痛抑制神经元放电的影响及电针对其调制作用[J]. 针刺研究, 1991,(1):19-22. DOI：

Sun Mingzhi, Li Yurong, Zhang Jiye, et al. EFFECTS OF NOXIOUS STIMULI ON THE DISCHARGES OF PAIN-EXCITATION NEURONS AND PAIN-INHIBITION NEURONS IN THE NUCLEUS VENTRALIS POSTEROLALIS OF THALAMUS IN THE RAT AND A MODULAING ACTION OF ELECTROACUPU-NCTURE ON ITS ELECTRIC ACTIVITIES[J]. Acupuncture research, 1991, (1): 19-22. DOI：

摘要

研究指出

丘脑腹后外侧核(VPL)可接受躯体伤害性传入信息

在VPL中可记录到对伤害性刺激出现放电增加和放电减少的痛反应神经元。表明VPL某些神经元对伤害性刺激的反应与丘脑非特异投射系统核团中痛反应神经元的活动相似The somatic and visceral noxious stimuli could simultaneously induce the increase of discharges of pain-excitation neutons (PEN) and the decrease of discharges of pain-inhibition neurons (PIN) in the Nucleus Ventralis posterolalis(VPL) of thalamus in the rat

and the electric activities of the two kinds of neurons cooperated each other. By the injection of morphine (5mg/kg) and the electroacupuncture of "Zusanli"

the discharges of PEN were reduced and the discharges of PIN were enhanced. The results suggested that VPL of thalamus in the rat be ifivolved in the modulating action on pain sensation and the analgesic effects of morphine and electroacupuncture by the simultaneous electric activities of PEN and PIN in VPL.

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