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1. 中国中医研究院针灸研究所
2. 中国中医研究院针灸研究所,北京,100700
纸质出版日期:1992
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高翠华, 孟竞璧, 付卫星, 等. 电针对实验性心绞痛时心肌氧代谢和冠状脉窦血液酸碱度的影响[J]. 针刺研究, 1992,(1):28-32.
Gao Cuihua, Meng Jingbi, Fu Weixing Song Liming. EFFECT OF ELECTROACUPUNCTURE ON MYOCARDIAL OXYGEN METABOLISM AND PH OF CORONARY SINUS BLOOD DURING EXPERIMENTAL ANGINA PECTORIS[J]. Acupuncture research, 1992, (1): 28-32.
高翠华, 孟竞璧, 付卫星, 等. 电针对实验性心绞痛时心肌氧代谢和冠状脉窦血液酸碱度的影响[J]. 针刺研究, 1992,(1):28-32. DOI:
Gao Cuihua, Meng Jingbi, Fu Weixing Song Liming. EFFECT OF ELECTROACUPUNCTURE ON MYOCARDIAL OXYGEN METABOLISM AND PH OF CORONARY SINUS BLOOD DURING EXPERIMENTAL ANGINA PECTORIS[J]. Acupuncture research, 1992, (1): 28-32. DOI:
冠心病心绞痛主要是由于冠脉血流减少
心脏血氧供应不能满足心脏的代谢需要而引起的。血氧供应不足时
心肌的代谢会发生一系列改变
酸性代谢产物增加
导致缺血局部pH值降低
严重者导致细胞内酸The experiments were performed on 30 healthy mongrel dogs
intubation was taken in the left anterior descending coroniary (LAD)
the blood in carotid was tran-sported to LAD through a peristalic pump
the blood flow was reduced to 3-5tnl/min
thus acute myocardial ischemia was produced. Basing on this condition
0.1-0.16ml bradykinin (2ug/ml) was gived into LAD coronary before recording to produce angina pectoris. The effects of electroacupuncture(EA) at "Neiguan" area on myocardial oxygen metabolism
pH of coronary sinus blood and myocardial contractile force were observed (EA intensity 5 volts
frequency 1-20 Hz). The results are as follows: 1. EA could reduce obviously A-V difference of blood oxygen capacity (Ca-vO_2) and the rate of myocardium extracting oxygen (O_2E)
thus reduced obviously oxygen consumption of ischemic myocardium. 2. EA could reduce V-A difference of carbon dioxide partial pressure (PvaCO_2)
prevent the decrease of pH of coronary sinus blood (PHv)
this indicated that EA could prevent accumulation! of acidic metabolic products. 3. EA could increase myocardial developed tension (DT) of ischemic area
strengthen myocardial contractile force of ischemic area. Above results indicated that EA could reduce oxygen consumption of ischemic myocardium
prevent the decrease of pH of coronary sinus blood
thus myocardial cell acidosis was prevented
myocardial contractile force was strengthened. It might be the mechanism of acupuncture treating coronary heart disease.
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