浏览全部资源
扫码关注微信
1. 白求恩医科大学生理教研室
2. 白求恩医科大学生理教研室,长春,130021
3. ,长春,130021
纸质出版日期:1992
移动端阅览
黄民, 刘敏芝, 李晓莹. 红核的镇痛作用及其机制的初步探讨[J]. 针刺研究, 1992,(3):166-170.
Huang Min, Liu Minzhi and Li Xiaoying. THE ANALGESIC EFFECT OF RED NUCLEUS AND PRELIMINARY RESEARCH ON ITS MECHANISM[J]. Acupuncture research, 1992, (3): 166-170.
传统的观念认为
红核的主要机能是调节躯体运动和肌紧张。但近年来有少量工作提示
红核与感觉的调制也有关。我们以往的工作证明
兴奋大鼠红核可使引起甩尾反The spontaneous discharges of neurons in red nucleus(RN) of rats have been recorded with microelectrode. The discharge frequency of most RN neurons was changed by nociceptive electrical stimulation of nervi peronaeus communis or nervi tibialis or by nociceptive mechanical stimulation of tail or hind leg. The electrical activities of the somatic snsory neurons in the nucleus ventrilis posterolateralis (VPL) of thalamus and of the visceral sensory neurons in the nucleus anterior and nucleus parafascicularis of thalamus have been recorded. According to the form of response to the peripheral nociceptive stimulation the neurons concerned could be divided into three types
pain-excited
pain-inhibited and pain-nonrelated. Electrical stimulating RN could change the spontaneous discharge frequency of somatic pain-related neurons of VPL and visceral painrelated neurons of nucleus anterior and nucleus parafascicularis
and could inhibit their response to somatic and visceral nociceptive stimulation respectively
but did not have influence on the activity of most pain-nonrelated neurons in VPL. The effects of electrical stimulating RN and microinjecting Ach into RN on the same pain-reated neuron in VPL were similar. The experimental results show that RN can receive the somatic afferent impulses
that the excited RN can inhibit the transmission of somatic and visceral nociceptive impulses into the thalamus
and that the analgesic effect of RN is concerned with Ach
0
浏览量
0
下载量
5
CNKI被引量
关联资源
相关文章
相关作者
相关机构