1. In normal control mice (only injected SRBC) after EA the lymphocyte transformation test (LTT

P<0.05) and interlukin-2 (IL-2) activity (P<0.05) were significantly increased

but the serum lysozytne (IZM

P<0.01) was apparantly decreased.2.After in jection of 6-OHDA in mice

the spleen weight

spleen index

thymus weight

thymusindex

spleen lymphocyte population and serum IZM

igG contents were marked deceaseds

Whereas LTT

IL-2 and plaque forming cell(PFC) were umchanged

In contrast

the thymus lymphocyte population was markedly increased.3. After EA of mice axotomized sympathetic nerve with 6-OHDA the above mentioned immune parameters deceased by 6-OHDA could be returned to normal or nearing normal levels.HOwever

the unchanged LTT

IL-2 and the increased thymus lymphocyte population could be enhanced further

especially IL-2.These results suggest that peripheral sympathetic nerve may be participation in the EA-mediating Anmunological responses