电针对去卵巢大鼠肾上腺核仁组成区蛋白的影响

陈伯英; 季士珠; 高慧; 何莲芳

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电针对去卵巢大鼠肾上腺核仁组成区蛋白的影响

更新时间：2023-08-11

- 电针对去卵巢大鼠肾上腺核仁组成区蛋白的影响
- The Effects of Electroacupuncture Treatment on Nucleolar Organizer Regions of Adrenal Cortex in Ovariectomized Rats
- 针刺研究 1994年第1期页码：46-50
- 作者机构：
  
  上海医科大学针刺原理研究所,200032
- 作者简介：
- 基金信息：
  
  国家自然科学基金
- DOI：
  中图分类号：
- 纸质出版日期：1994
- 稿件说明：
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陈伯英, 季士珠, 高慧, 等. 电针对去卵巢大鼠肾上腺核仁组成区蛋白的影响[J]. 针刺研究, 1994,(1):46-50.

The Effects of Electroacupuncture Treatment on Nucleolar Organizer Regions of Adrenal Cortex in Ovariectomized Rats[J]. Acupuncture research, 1994, (1): 46-50.
陈伯英, 季士珠, 高慧, 等. 电针对去卵巢大鼠肾上腺核仁组成区蛋白的影响[J]. 针刺研究, 1994,(1):46-50. DOI：

The Effects of Electroacupuncture Treatment on Nucleolar Organizer Regions of Adrenal Cortex in Ovariectomized Rats[J]. Acupuncture research, 1994, (1): 46-50. DOI：

摘要

用组织学定量分析方法观察了电针穴位后，去卵巢大鼠的肾上腺皮质内侧区细胞核仁组成区银染蛋白（AgNORs）数目明显增多，肾上腺体积和重量增加；阴道涂片出现雌激素样反应，上皮细胞成熟脱落。正常大鼠电针后未发现有相同的反应。本文结果提示，电针可能促进去卵巢大鼠肾上腺内侧区细胞的合成代谢，增加肾上腺源性雄激素的分泌，雄激素可在体内某些组织中转化为雌激素，对因切除卵巢所致的体内雌激素不足，起一定的代偿作用。

Abstract

The present paper reports the morphometric analysis of nucleolar organizer regions (NORs) of the adrenal cortex in ovariectomized rats following electroacupuncture (EA) using argyrephil (AgNOR) method for NORs. Animals were divided into four groups

the control group (CT group

n=4)

the EA group (n=3)

the ovariectomized group (OV group

n=4) and the ovariectomized electroacupuncture group

(OV+EA group

n=7). The number of AgNORs of 100 cells from zona fasciculata of the adrenal cortex in each case of all groups was counted at random and the mean±SE (number/cell)in each group was calculated as follows: OV+EA group 2. 71±0. 26

OV group 1. 62±0. 15

EA group 1. 21 ± 0. 04 and CT group 1. 48±0. 03. The mean of AgNORs in OV+EA group differed highly significantly from the other three groups (P<0. 01) tested by ANOVA and LSD method

No significant distinction was found among the OV group

EA group and CT group.Gross specimen examination showed that adrenal glands in OV+EA were significantly heavier than those in the other three groups (P<0. 01). Vaginal smears showed that a response like that of estrogen-induced with exfoliative cells appeared in the OV+EA group rats following EA.EA had no influence on the change of exfoliative cells in EA group.The results suggest that EA may promote the synthesis and secretion of the adrenal steroid hormones

the androgen of which will then be transformed into estrogen in other tissues

thus compensating the deficiency of estrogen induced by ovariectomy

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