The experiment were performed on model rabbits injected with large dosage of Dexamethasone(DXM)for 5 days.Reinforcing manipulation(RIM)

reducing manipulation(RDM)

and electricstimulation(ES)were respectively used to puncture Zusanli(ST 36)points for 5 days to observe thechange on temperature

body weight

corticosterone assay

testosterone assay

and the amplitute ofthe plethysmogram.The result showed that there was a similar syndrome of the kidney deficiency after injectingDXM.The body weight was increased in the DXM control group

decreased in the RDM group andhad no significant influence in the other groups.The body weights between the reinforcing manipula-tion and the reducing manipulation groups had obvious difference.But the other indices of observationhad no significant influence among the different groups.So there wasn't significant diference on mostof observed signs among the RIM group

the RDM group and ES group.The study of acupuncturemanipulation will have yet to be further done.