It is well known that acupuncture is effective for treatment of gastric disease in human. We have observed the effect of acupunctureing" Zhongwan"" Neiguan" "Zusanli" on fluorohistochemical changes of G cells of antral mucosa in 42 patients with gastric diseass. The results show that after acupuncture treatment the amount of fluorescent G cells and the fluoresent intensity of gastrin in the G cells were obviously decreased in patients with duodenal ulcer
as compared with that before acupuncture treatment. However
the amount of G cells was increased by acupuncture treatment in patients with chronic atrophic gastritis.These data indicate the acupuncture may regulate G cell from abnormal to normal condition in gastric mucosa of gastric disease.