Cr+3 or V+5 are injected into acupoint of mice for pretreatment and then pentobarbital sodium injected into the same points
it is found that the element Cr+3may shorten time of onset sleeping and prolong time of maintenance sleeping of injecting pentobarbital sodium at ″Zusanli″pcint
while the element V+5may shorten time of onset sleeping and proong time of maintenance sleeping of injecting pentobarbital sodium at "Neigran"point. It indicates different trace elements can produce different influence on acupoint drug effect entering "Zusanli"or "Neiguan" point. The results mentioned above suggest that the different respones of different acupoints to same drug may be relaeted to the different ion structures or different semi-conductive properties of the different acupoints.