电针对大鼠应激性胃溃疡保护过程中中枢及外周单胺类神经递质的影响

沈德凯; 刘冰怀; 韦多; 章复清; 陈亦宜

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电针对大鼠应激性胃溃疡保护过程中中枢及外周单胺类神经递质的影响

更新时间：2023-08-11

- 电针对大鼠应激性胃溃疡保护过程中中枢及外周单胺类神经递质的影响
- Effects of electroacupuncture On Central And Peripheral Monoamine Neurotransmitter In the Course of Protecting Rat Stress Peptic Ulcer
- 针刺研究 1994年第1期页码：51-54
- 作者机构：
  
  安徽中医学院针灸经络研究所,合肥,230038
- 作者简介：
- 基金信息：
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- 纸质出版日期：1994
- 稿件说明：
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沈德凯, 刘冰怀, 韦多, 等. 电针对大鼠应激性胃溃疡保护过程中中枢及外周单胺类神经递质的影响[J]. 针刺研究, 1994,(1):51-54.

Effects of electroacupuncture On Central And Peripheral Monoamine Neurotransmitter In the Course of Protecting Rat Stress Peptic Ulcer[J]. Acupuncture research, 1994, (1): 51-54.
沈德凯, 刘冰怀, 韦多, 等. 电针对大鼠应激性胃溃疡保护过程中中枢及外周单胺类神经递质的影响[J]. 针刺研究, 1994,(1):51-54. DOI：

Effects of electroacupuncture On Central And Peripheral Monoamine Neurotransmitter In the Course of Protecting Rat Stress Peptic Ulcer[J]. Acupuncture research, 1994, (1): 51-54. DOI：

摘要

本文研究了电针对大鼠应激性胃溃疡保护过程中单胺类神经递质的作用，结果为电针对大鼠应激性胃溃疡具有较好的保护作用。电针组中枢和外周5－HT的合成和分解受到抑制；中枢各脑区及血液中NE水平都较对照组为高，而胃组织中NE较对照组低；胃及血液中DA水平电针组明显高于对照组。结果表明，中枢及外周的单胺类神经递质参与了电针保护大鼠应激性胃溃疡的过程。

Abstract

The experimental Wistar rats were divided into two groups

the acupuncture group and the control group. Stress-induced gastric ulcer models were established by immersion of restrained rats in water. The results are as follows: 1. Stress-induced peptic ulceration was able to be protected with electroacupuncture. 2.Synthesis and decomposition of central and peripheral 5-HT in the electroacupunctured tats was inhibited. 3. The NE levels in the three brain regions (cortex

hypothalamus

brainstem)and blood were seen in the electroacupuncture group more than that in the control group

but the NE levels was smaller in the gastric tissue. 4. The higher levels of DA in the gastric tissue and blood were seen in the electroacupuncture group than in the control group. The results indicated that protecting rat stress ulceration with electroacupuncture was connected with monoamine neurotransmitter of centre and periphery

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