育亨宾鞘内注射对电针镇痛及脑内β-内啡肽释放的抑制

陈明辉; 庄婉俐; 黄显奋

您当前的位置：

首页 >

文章列表页 >

育亨宾鞘内注射对电针镇痛及脑内β-内啡肽释放的抑制

更新时间：2023-08-11

- 育亨宾鞘内注射对电针镇痛及脑内β-内啡肽释放的抑制
- The Inhibition of Yohimbine Injected Intrathecally on Electroacupuncture-induced Analgesia and Release of β-endorphin from Rat Brain
- 针刺研究 1996年第1期页码：52-55
- 作者机构：
  
  1. 上海医科大学神经生物教研组,上海,200032
  2. 上海华东医院
- 作者简介：
- 基金信息：
- DOI：
  中图分类号：
- 纸质出版日期：1996
- 稿件说明：
移动端阅览
陈明辉, 庄婉俐, 黄显奋. 育亨宾鞘内注射对电针镇痛及脑内β-内啡肽释放的抑制[J]. 针刺研究, 1996,(1):52-55.

The Inhibition of Yohimbine Injected Intrathecally on Electroacupuncture-induced Analgesia and Release of β-endorphin from Rat Brain[J]. Acupuncture research, 1996, (1): 52-55.
陈明辉, 庄婉俐, 黄显奋. 育亨宾鞘内注射对电针镇痛及脑内β-内啡肽释放的抑制[J]. 针刺研究, 1996,(1):52-55. DOI：

The Inhibition of Yohimbine Injected Intrathecally on Electroacupuncture-induced Analgesia and Release of β-endorphin from Rat Brain[J]. Acupuncture research, 1996, (1): 52-55. DOI：

摘要

鞘内注射α2受体拮抗剂育亨宾（30μg／8μl）可明显抑制电针镇痛，作用维持15分钟，作用最强时痛阈降至佯针水平，此时，电针所引起的侧脑室灌流液中β-内啡肽含量的升高也被抑制，β-内啡肽含量降至佯针水平，而育亨宾本身对基础痛阈及灌流液中β-内啡肽含量均无影响。结果提示，电针镇痛其所引起的β-内啡肽的释放与脊髓α2受体的激活有关。

Abstract

Yohimbine (30μg/8μl

ith )

an antagonist of α2-adrenergic receptor

can inhibit electroacupuncture-induced analgesia (EAA) for 15 min

with its biggest effect reducing the pain threshold of electroacupuncture (EA) to the level of sham electroacupuncture (SEA). Yohmbine also completely inhibit the increase of 3-endorphin in the push-pull liquids from ventriculus lateralis cerebri caused by EA. But yohirnbine itself produce no effect on pain threshold and the concentration of 3-endorphin. These results suggest that EAA and the increased release of β-endorphin caused by EA are related to the activation of α2-adrenergic receptor in the spinal cord

关键词

Keywords

references

浏览量

下载量

CNKI被引量

文章被引用时，请邮件提醒。

提交

工具集

关联资源

暂无数据