金黄地鼠38只，雌雄各半，随机分成正常对照、正常治疗、模型、模型加治疗四组。正常对照组和正常治疗组喂饲普通全阶鼠饲料；模型和模型加治疗组喂饲致石饲料30天，使金黄地鼠胆石症由其自然发生率50％提高到100％（P＜0．05）。治疗在第30天开始，分别电针正常治疗组和模型治疗组地鼠的阳陵泉穴和期门透日月穴，10min／次，每日一次，共七次。结果显示：（1）电针能使地鼠胆石症的自然发生率从50％降至10％，结石数量显著减少（P＜0．05），巨大结石数降为0（P＜0．01）；使模型鼠的胆石症发生率及结石数、巨大结石数显著降低（P＜0．05，P＜0．01）。（2）电针可显著降低模型鼠血清和胆汁中胆固醇的含量（P＜0．05），并显著增加胆汁中胆酸的含量（P＜0．05）；对正常地鼠胆固醇虽有降低，但与针组比较无统计学意义。（3）另对10只正常金黄地鼠电针后发现，电针使地鼠奥狄氏括约肌肌电的节律性活动明显增加（P＜0．01，P＜0．05），频率显著加快（P＜0．01，P＜0．05），以及胆汁分泌显著增加（P＜0．01，P＜0．05），并可维持针效达30～45min。本文结果提示：电针有关穴位能降低血液及胆汁中的胆固醇含量，增加胆酸的含量，从而抑制胆汁中胆固醇结晶的析出，并通过加强奥狄氏括约肌的节律性收缩及增In this study

the 38 golden hamsters

male and female each half

were divided into four groups:the control and control treating groups to feed normal foods; cholelithiasis model and model treating groups to feed special diet

which made high fat

high cholesterol and high carbohydrates to cause the cholelithiasis model of hamsters. After 30 day

the natural formation rate of gallstone rose to 50% (contral group)

while model group

the formation rate was 100%.On the 30th day

the treatment was carried out. The control treating group and model treating group were acupuntured at Yanglingquan(G 34)and Qimen(Liv 14)through Riyue(G 24)on the right side of body respectively by electrotherapy. The period of treatment was total 7 days

once everyday and 10 min every once. The results showed: (1) In control treating group

the natural formation rate of gallstone of normal hamsters was dropped from 50 % to 10%

the number of gall-tones was reduced markedly(P < 0. 05) and number of huge gallstones was dropped to zero (P < 0. 01). (2) In the cholelithiasis model treating group

the treatment of electrotherapy could signiflcantly reduced the formation rate of cholelithiasis

the number of gallstones and the huge gall-stones(P< 0. 05 or P< 0. 01).Also

content of the cholesterol in plasma and bile were reduced

but the contents of the cholic acid secreted from the liver were obviously increased in the model hamsters. It was significant difference to compared with model group(P all< 0. 05). (3) The electrotherapy increased the rhythmic actions and frequency of Oddi's sphincter electromyogram markedly(P< 0. 05

P< 0. 01) as well as secretion of hepatic bile(P<0. 05

P<0. 01). The effects of electrotherapy could continued 30 to 40 minutes.The results suggest that some points to acupuncture with electrotherapy can reduce the contents of cholesterol in plasma and bile

and increase the volumes of secretion of cholic acid

thus inhibit the crystallization of cholesterol from bile. At the sometime

the electrotherapy causes the rhythmic contractions of Oddi's sphincter and increase the secretion of bile

so the gallstones are discharged on its own initiative. Therefore the cholelithiasis is cured by acupuncture