电针及经皮电刺激治疗糖尿病神经病变的实验研究

莫孝荣; 陈丁生; 吉长福; 张金铃; 刘长宁; 朱丽霞

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电针及经皮电刺激治疗糖尿病神经病变的实验研究

更新时间：2023-08-11

- 电针及经皮电刺激治疗糖尿病神经病变的实验研究
- Effect of Electro-acupuncture and Transcutaneous Electric Nerve Stimulation on Experimental Diabetes and its Neuropathy
- 针刺研究 1996年第3期页码：55-59
- 作者机构：
  
  1. 中国中医研究院针灸研究所,北京
  2. ,100700
- 作者简介：
- 基金信息：
- DOI：
  中图分类号：
- 纸质出版日期：1996
- 稿件说明：
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莫孝荣, 陈丁生, 吉长福, 等. 电针及经皮电刺激治疗糖尿病神经病变的实验研究[J]. 针刺研究, 1996,(3):55-59.

Effect of Electro-acupuncture and Transcutaneous Electric Nerve Stimulation on Experimental Diabetes and its Neuropathy[J]. Acupuncture research, 1996, (3): 55-59.
莫孝荣, 陈丁生, 吉长福, 等. 电针及经皮电刺激治疗糖尿病神经病变的实验研究[J]. 针刺研究, 1996,(3):55-59. DOI：

Effect of Electro-acupuncture and Transcutaneous Electric Nerve Stimulation on Experimental Diabetes and its Neuropathy[J]. Acupuncture research, 1996, (3): 55-59. DOI：

摘要

本文用腹腔注射链脲佐菌素（50mg／kg）诱发大鼠实验性糖尿病，48小时后血糖升高（11．1－33．3mmol／L），出现多饮、多食和多尿现象。随机分为三组，分别给以电针（EA）和经皮电刺激（TENS）治疗，取穴双侧肾俞和足三里，每次20分，每周三次，共五周；DM组未给治疗，另设ND组。到六周末治疗组血糖下降，和DM组相比，EA组差异显著（P＜0．05），三多症状也有明显改善；但TENS组没有显著差异。在四周和六周末，DM组运动神经传导速度较正常动物明显减慢（P＜0．05），而EA组和TENS组分别于四周和六周时恢复正常，与DM组比较差异显著（P＜0．05）。DM组和TENS组在造模后基础痛阈一度出现降低（痛敏），而EA组痛阈不但不降反而升高，与DM组和TENS组相比，差异显著（P＜0．05）。本实验肯定了电针对实验性糖尿病的治疗作用，为推广针灸治疗糖尿病及其神经病变提供了实验依据。

Abstract

In this paper

the experimental diabetic rats induced by streptozotocin (STZ

i. p. 50 mg/kg)were divided into three groups

electro-acupuncture (EA group

n = 8)

transcutaneous electric nervestimulation (TENS group

n = 8)

at bilateral Shenshu and Zusanli points for 20 minutes once every 2- 3 days for five weeks

and without any treatment (DM group

n = 6) respectively. As compared withthe DM group

the increased plasma glucose levels was lowered significantly in EA group (P< 0. 05)and slightly in TENS group(P >0. 05) by the end of the sixth week. And the symtoms of polyphagia

polydipsia and polyuria were attenuated in EA group. The motor nerve conduction velocity slowing wasprevented or corrected after a course of four and six weeks treatment in EA and TENS group respec-tively. In the DM and TENS groups the pain threshold was lowered at 6 - 20 days after injection ofSTZ

but elevated in EA group

their differences were of significance (P< 0. 05). In general

the effi-ciency of EA treatment on experimental diabetes and its neuropathy was better than that of TENStherapy.

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