A model of the reducible movement of stomach in a big mouse was set up by injecting solution of 654-2. At first

the state of stomach movement was proved to be improved by acupuncture. After that

the activity of CaM in Zusanli point wirs lost by injecting TFP and effect of acupuncture on the stomach movement was studied. The result showed that the effect of acupuncture was abolished during manipulating the needles for 5 minutes. But retaining the needle for 25 minutes

the effect of acupuncture was recovered gradually. It indicates that the activity of Ca-CaM compounds may be of the key factor of acupuncture effect and one of the important links of the functional activity of meridians and collaterals.