酸性磷酸酶检测对针刺治疗实验性脊髓损伤的评价

晋志高; 陶之理; 任文庆; 杜香莲

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酸性磷酸酶检测对针刺治疗实验性脊髓损伤的评价

更新时间：2023-08-11

- 酸性磷酸酶检测对针刺治疗实验性脊髓损伤的评价
- Electro-acupuncture Effects on Experimental Spinal Cord Injury of the Cat as Evaluated by Acid Phosphatase Detection
- 针刺研究 1996年第4期页码：50-53
- 作者机构：
  
  中国中医研究院针灸研究所,北京,100700
- 作者简介：
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- 纸质出版日期：1996
- 稿件说明：
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晋志高, 陶之理, 任文庆, 等. 酸性磷酸酶检测对针刺治疗实验性脊髓损伤的评价[J]. 针刺研究, 1996,(4):50-53.

Electro-acupuncture Effects on Experimental Spinal Cord Injury of the Cat as Evaluated by Acid Phosphatase Detection[J]. Acupuncture research, 1996, (4): 50-53.
晋志高, 陶之理, 任文庆, 等. 酸性磷酸酶检测对针刺治疗实验性脊髓损伤的评价[J]. 针刺研究, 1996,(4):50-53. DOI：

Electro-acupuncture Effects on Experimental Spinal Cord Injury of the Cat as Evaluated by Acid Phosphatase Detection[J]. Acupuncture research, 1996, (4): 50-53. DOI：

摘要

本文用实验神经生物学方法对针刺治疗截瘫作了初步的研究。用Allen氏致伤法损伤成年猫腰1节段脊髓，伤后动物出现截瘫，随机分为两组，（1）电针组，伤后4小时给以电针治疗，选穴：双侧足三里，双侧环跳及损伤部位上下各一夹脊穴；刺激强度6mA50Hz；每日一次，持续20分钟；（2）对照组，不作任何治疗。损伤后3天和7天动物分别作酸性磷酸酶组织化学检测，电针组该酶的含量均高于对照组，两组间存在非常明显的差异（P＜0.05，P＜0．01）。该结果提示电针可使损伤脊髓内酸性磷酸酶水平明显升高，ACP含量的增加可提高酪氨酸磷酸化的水平而刺激细胞的生长。ACP可能起到在损伤早期促进损伤而在损伤恢复期又促进再生的双重作用。

Abstract

The spinal cords of adult cats were injured at about L1 level by using Allen's method and the animals were divided randomly into 2 groups . a) electro-acupuncture treatment group and b) control group. The acid phosphatase (ACP) was detected at 3 and 7 days after spinal cord injury. The more ACP positive labelings were found in the treatment group than in the control group at both 3 (P<0.05 )and 7 days (P< 0.01) after injury. The results suggested that electro-acupuncture could increase the concentration of ACP of the injured spinal cord and the increased ACP concentration could make worse to the injured spinal cord at early time and improve regeneration during recovery perlod

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电针在脊髓损伤修复中的应用基础研究概况