Experimental Parkinson's disease in rats was treated with point injection with different reagents on bilateral "Yang Lingquan (GB 34)". The results indicated that the times of rotation induced by apomorphinum were remarkably reduced no matter whether extra dopamine was given or not. The degree of reduction of rotation was closely related to increase of DA in the striatum. Though the change of serotonin had no significant correlation with the change of times of rotation

dopamine had significant positive correlation with the numbers of rotation. These findings suggest that point injection at experimental Parkinson's disease had significant correlation with dopamine

and related to serotonin and harmony of neurotransmitters in striatum.