One hundred patients undergoing renal transplantation were randomly divided into combined acupuncturesepidural anesthesia group (group A

points selected: Ciliao

Sanyinjiao

Taixi together with Shenshu and para-incision or Zusanli; combined with small dose of epidural block) and epidural block group(group C)

each 50 patients. The initial dose and total dose of local anesthetics were 5. 6±0 .3m1 and 13. 5±1. 0ml in group A

and 14. 5±0. 4ml and 25. 4±1. 2ml in group C

respectively.There was very significant difference between the two groups(P < 0.001). During the operation the hemodynamic changes were greater in group C. Ephedrine and atropine were used in 1 and 2 cases in group A

and in 9 and 5 cases in group C

respectively. The starting time of urination of the trans-planted kidney was shorter in group A than in group C

being 209±25s and 410±47s

respectively(P< 0. 001 ). There was no significant difference in the indices of immunologic function between the two groups. The anesthetic results in group A were evaluated according to the initial dose of epidural anes-thetics. Those were excellent in 31 cases(62 % ) and good in 13 (26 % ) with the excellent-good rate 88 %.