电针对脑缺血大鼠体感诱发电位及脑梗塞体积的影响

司全明; 吴根诚; 曹小定

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电针对脑缺血大鼠体感诱发电位及脑梗塞体积的影响

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- 电针对脑缺血大鼠体感诱发电位及脑梗塞体积的影响
- Effect of Electroacupuncture on Somatosensory Evoked Potentials and Infarct Volume after Middle Cerebral Artery Occlusion in Rats
- 针刺研究 1998年第1期页码：36-40
- 作者机构：
  
  上海医科大学医学神经生物学国家重点实验室,上海,200032
- 作者简介：
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- 纸质出版日期：1998
- 稿件说明：
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司全明, 吴根诚, 曹小定. 电针对脑缺血大鼠体感诱发电位及脑梗塞体积的影响[J]. 针刺研究, 1998,(1):36-40.

Effect of Electroacupuncture on Somatosensory Evoked Potentials and Infarct Volume after Middle Cerebral Artery Occlusion in Rats[J]. Acupuncture research, 1998, (1): 36-40.
司全明, 吴根诚, 曹小定. 电针对脑缺血大鼠体感诱发电位及脑梗塞体积的影响[J]. 针刺研究, 1998,(1):36-40. DOI：

Effect of Electroacupuncture on Somatosensory Evoked Potentials and Infarct Volume after Middle Cerebral Artery Occlusion in Rats[J]. Acupuncture research, 1998, (1): 36-40. DOI：

摘要

本实验在大脑中动脉阻塞（MCAO）及再灌注动物模型上，观察缺血后电针对大鼠体感诱发电位（SEP）和脑梗塞体积的影响。结果发现缺血组和缺血后电针组在MCAO后30分钟，缺血侧SEP波幅降至缺血前的2．2±3％，1．9±2％，缺血后再灌注7天，SEP恢复至缺血前的25．5±14．1％，58．6±27．2％，两组比较P＜0．05；脑梗塞体积分别为70．72±25．4mm3，45．65±11．4mm3（P＜0．05）。结果提示电针可促进脑缺血后SEP的恢复，减少脑缺血性组织坏死。

Abstract

The model of reversible middle cerebral artery occlusion(MCAO) was used to study the effect of electroacupuncture(EA) on somatosensory evoked potential (SEP) and infarct volume after MCAO in rats. After 1 hour of MCAO

EA was applied at the points of Fengfu(DU 16)and Renzhong(DU 26).The results were as follows: (1) In MCAO group and MCAO + EA group the amplitude of SEP on the ipsilateral side of MCAO was nearly abolished at 30 min after MCAO and recovered to 25.5±14.1%

58. 6±27. 2 % (P <0.05)on day 7 after reperfusion. (2) The infarct volume in MCAO group and EA + MCAO group was 70. 72±25. 4mm3

45. 65±11. 4mm3 (P <0.05) respectively after reperfusion 7 days following MCAO 2 hours.The results above indicate that EA might produce cerebroprotective effect after focal cerebral ischemia.

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