S_(180) solid tumor models in mice were established to observe the antineoplastic effects of moxibustion. The study shows that the moxibustion on the point of "Guanyuan" and cutting into the subcuta- neous tissue with surgical knife blade after moxibustion on the location of the tumor could hinder the growth of the tumor

thus heightened the survival rate and prolonged the duration of life of the mice. A more than 33 % rate of inhibition in treating the tumor was gained. It is also showed that the therapy improved the proliferative reaction of the splenic lymphocyte induced by the ConA and LPS

and improved the activity of IL-1 and IL-2. All these effects have statistical significance as compared with that of the control group

and were equal or superior to that of cyclophosphamide(CY). The results indicate that the thermotherapeutic effect

the effect of eliminating the stagnation and activiting the blood

the heightening of the immune function may all play a role in the moxibustion's antineoplastic effects.